Neurocognitive Rehabilitation of Down Syndrome

by Rondal, Jean-adolphe; Perera, Juan; Spiker, Donna

• ISBN13: 9781107400436
• ISBN10: 1107400430
• Format: Paperback
• Copyright: 2011-07-11
• Publisher: Cambridge Univ Pr

Summary

Down syndrome is one of the most commonly occurring developmental disorders and it is now possible to conceptualize and define opportunities for neurocognitive rehabilitation for those with the condition. This book describes how early cognitive intervention in children with Down syndrome can be carried out, and can reduce, or compensate for, the major deficits characteristic of the condition. This comprehensive account relates the neurocognitive approach to the major therapeutic endeavors in the neighboring fields of neurogenetics, experimental environmental enrichment, molecular genetics, pharmacology, pediatrics and cardiology for infants with Down syndrome. Neurocognitive Rehabilitation of Down Syndrome provides the guidance required to establish effective rehabilitation programs, and is essential reading for developmental clinicians, pediatricians, neuropsychologists and other health professionals.

Table of Contents

Preface

Definition, History, Methodology, and Assessment

Early intervention: definition, objectives, models and challenges

The history of rehabilitative intervention for infants and young children with Down syndrome and their families: where have we been and where are we going?

Advances in clinical endpoints for neurocognitive rehabilitation in Down syndrome

Genetics, Brain and Animal Models

New perspectives on molecular and genetic therapies in Down syndrome

Brain plasticity and environmental enrichment in Ts65Dn mice, an animal model for Down syndrome

Development of the brain and metabolism

Pharmacological and Medical Management and Treatment

Pharmacotherapy for children with Down syndrome

Early medical caretaking and follow-up

Evaluation and management of cardiovascular diseases in Down syndrome

Early Development and Intervention

Developmental models as frameworks for early intervention with children with Down syndrome

Aspects of motor development in Down syndrome

Memory development and learning

Prelinguistic and early development, stimulation and training in children with Down syndrome

Speech perception, stimulation and phonological development

Goal-directedness as a target for early intervention in Down syndrome

The role of parents of children with Down syndrome and other disabilities in early intervention

Therapeutic Perspectives

Perspectives of hybrid therapeutic strategies in intellectual disabilities and Down syndrome

Conclusions

Index

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