Neuroglia

by Kettenmann, Helmut; Ransom, Bruce R.

• ISBN13: 9780195152227
• ISBN10: 0195152220
• Edition: 2nd
• Format: Hardcover
• Copyright: 2004-09-30
• Publisher: Oxford University Press

Summary

Neuroglia is the only comprehensive reference book on the basic biology and function of glial cells. This long-awaited second edition has been completely reorganized and rewritten to include the dramatic advances in this field since the first edition was published ten years ago. The impactof the second edition will be greater than that of the first because the majority of neuroscientists now acknowledge that neuroglia are elemental to most, if not all, brain functions. The second edition covers the entire field of glial research from the basic molecular and cellular principles ofthese cells to their involvement in neurological diseases including stroke, Alzheimer's disease, and multiple sclerosis. It includes new chapters on transmitter release from exocytosis from glia, glia derived stem cells, glia and synaptic transmission, glia and axon guidance, an entirely newsection on mechanisms of glial injury, and several new chapters on the roles of glia in different diseases. The new edition was written with both students and experts in mind. It provides a basic introduction to the entire range of glial topics and detailed information with critical assessment ofthe research literature. Neuroscience textbooks focus on the properties of neurons, whereas this book fills the information void about the brain's other cells. Neuroglia, Second Edition, is an essential reference source for newcomers, including graduate students, to neuroanatomy, neurochemistry,neurophysiology, and molecular neurobiology. It is also a vital companion for established researchers in these fields as well as clinicians in neurology, neurosurgery, psychiatry, neuropathology, and neuro-oncology.

Table of Contents

Contributors	xv
The Concept of Neuroglia: A Historical Perspective	1	(18)
Helmut Kettenmann
Bruce R. Ransom
PART I PROPERTIES OF NEUROGLIAL CELLS
Morphology and Ultrastructure of Glial Cells
Astrocytes and Ependymal Glia	19	(17)
Andreas Reichenbach
Hartwig Wolburg
Structure and Function of Oligodendrocytes	36	(12)
Arthur M. Butt
Schwann Cells and Myelin	48	(12)
Rudolf Martini
Microglial Cells	60	(12)
Wolfgang J. Streit
Lineage
Lineages of Astrocytes and Oligodendrocytes	72	(13)
James E. Goldman
The Schwann Cell Lineage	85	(16)
Kristjan R. Jessen
Rhona Mirsky
The Role of Neurogenic Astroglial Cells in the Developing and Adult Central Nervous System	101	(11)
Stephen C. Noctor
Lidija Ivic
Veronica Martinez-Cerdeno
Arnold R. Kriegstein
Physiological and Biochemical Properties
Voltage-Activated Ion Channels in Glial Cells	112	(19)
Michelle L. Olsen
Harald W. Sontheimer
Receptors for Neurotransmitters and Hormones	131	(15)
Helmut Kettenmann
Christian Steinhauser
Cytokine and Chemokine Receptors and Signaling	146	(17)
Duane R. Wesemann
Etty N. Benveniste
Mechanisms of Solute Transport in Glia	163	(14)
Neville Brookes
Gap Junctions and Hemichannels	177	(13)
Bruce R. Ransom
Zu-Cheng Ye
Quantal Release of Transmitter: Not Only from Neurons but from Astrocytes as Well?	190	(12)
Andrea Volterra
Jacopo Meldolesi
Enzymes of Carbohydrate and Energy Metabolism	202	(14)
Bernd Hamprecht
Stephan Verleysdonk
Heinrich Wiesinger
Second Messenger Systems	216	(13)
Sean Murphy
Brian R. Pearce
Intracellular Calcium Control Mechanisms in Glia	229	(11)
Marisa Luisa Cotrina
Maiken Nedergaard
Cytoskeletal Proteins in Astroglia	240	(13)
Lawrence F. Eng
Yuen Ling Lee
PART II FUNCTIONS OF NEUROGLIAL CELLS
Myelin
Molecular Biology of Myelination	253	(11)
Anthony T. Campagnoni
Factors Controlling Myelin Formation	264	(9)
Lynn D. Hudson
Myelin Function and Saltatory Conduction	273	(12)
Stephen G. Waxman
Lakshmi Bangalore
Immune Function
Cytokine Production	285	(17)
Francesca Aloisi
Interaction of Glial Cells with Monocytes	302	(12)
Ingo Bechmann
Robert Nitsch
Antigen Processing, Presentation, and T Cell Interaction	314	(11)
Harald Neumann
Blood-Brain Barrier
The Role of Glia in the Formation and Function of the Blood-Brain Barrier	325	(9)
Hannelore Bauer
Hans-Christian Bauer
Reiner F. Haseloff
Ingolf E. Blasig
Influence on Neurons
Extracellular Potassium and pH: Homeostasis and Signaling	334	(12)
Jonathan A. Coles
Joachim W. Deitmer
Astrocyte Neurotransmitter Uptake	346	(9)
Raymond A. Swanson
Glia and Synaptic Transmission	355	(12)
Eric A. Newman
The Central Role of Astrocytes in Neuroenergetics	367	(10)
Luc Pellerin
Pierre J. Magistretti
Growth Factors for Neurons Provided by Macroglial Cells	377	(12)
Bernhard Reuss
Klaus Unsicker
Development
Radial Glial Cells: Scaffolding for Cortical Development and Evolution	389	(16)
Pasko Rakic
Axon Guidance	405	(16)
Andreas Faissner
PART III DISEASE AND NEUROGLIAL CELLS
Mechanisms of Glial Injury
Astrocyte Injury	421	(9)
Christopher J. Feeney
Peter K. Stys
Oligodendrocyte and Schwann Cell Injury	430	(13)
Jennifer K. Ness
Mark P. Goldberg
Response of Microglia to Brain Injury	443	(11)
Kazuyuki Nakajima
Shinichi Kohsaka
Recovery of Neural Function
Axonal Regeneration in the Peripheral Nervous System of Mammals	454	(13)
Olawale A.R. Sulaiman
J. Gordon Boyd
Tessa Gordon
Axonal Regeneration in the Central Nervous System of Mammals	467	(10)
Isabel Klusman
Martin E. Schwab
Transplantation of Myelin-Forming Cells	477	(12)
William F. Blakemore
Robin J.M. Franklin
Diseases
Multiple Sclerosis	489	(12)
Jack Antel
Douglas Arnold
Human Immunodeficiency Virus Infection of the Central Nervous System	501	(10)
Elena Ryzhova
Dennis L. Kolson
Francisco Gonzalez-Scarano
Focal Cerebral Ischemia: The Multifaceted Role of Glial Cells	511	(10)
Ulrich Dirnagl
Josef Priller
Gliomas	521	(11)
Michael Weller
Neurological Mouse Mutants: A Molecular-Genetic Analysis of Myelin Proteins	532	(18)
Klaus-Armin Nave
Ueli Suter
Astrocytic Swelling in Neuropathology	550	(13)
Alexander A. Mongin
Harold K. Kimelberg
The Activation of Microglia as an Early Sign of Disease Progression in Alzheimer's Disease	563	(10)
Robert Veerhuis
Jeroen J.M. Hoozemans
Annachiara Cagnin
Piet Eikelenboom
Richard B. Banati
Peripheral Neuropathy and the Schwann Cell	573	(13)
Rita M. Cowell
James W. Russell
Reaction of Glial Cells in Infectious Disorders of the Central Nervous System	586	(7)
Martina Deckert
Dirk Schluter
Index	593