New Concepts in the Immunopathogenesis of Cns Infections

by Peterson, Phillip K.; Remington, Jack S.

• ISBN13: 9780632045280
• ISBN10: 0632045280
• Format: Hardcover
• Copyright: 2000-08-01
• Publisher: John Wiley & Sons Inc

Summary

Univ. of Minnesota, Minneapolis. Discusses topics related to the immunopathogenesis of infections of the brain. Gives the reader an understanding, at the molecular level, of the strategies used by the host to defend the brain. Direction for future research is incorporated. DNLM: Central Nervous System Diseases--etiology.

Table of Contents

Contributors	vi
Preface	xiii
Entry and Function of Hematogenous Cells in the Central Nervous System	1	(20)
William F. Hickey
Astrocytes and the Neuroimmunomodulatory Role of Interleukin-6	21	(18)
Etty N. Benveniste
Nicholas J. Van Wagoner
Microglia: Defenders of the Brain Against Viral Infection	39	(12)
James R. Lokensgard
Maxim C-J. Cheeran
Shuxian Hu
Genya Gekker
Phillip K. Peterson
Cytokines and Chemokines in Defense and Damage in the Intact CNS	51	(33)
Iain L. Campbell
Bacterial Meningitis: Epidemiology, Pathophysiology, and Immunobiology	84	(23)
W. Michael Scheld
Experimental Tuberculous Meningitis	107	(12)
Liana Tsenova
Victoria H. Freedman
Gilla Kaplan
Neurologic Lyme Disease	119	(24)
Julie Antique
Benjamin J. Luft
Patricia K. Coyle
Immunopathogenesis of CNS Toxoplasmosis	143	(20)
Yasuhiro Suzuki
Jack S. Remington
Cryptococal Meningoencephalitis	163	(25)
Arturo Casadevall
David L. Goldman
Sunhee Lee
Herpes Simplex Infections of the Central Nervous System	188	(17)
Ann Arvin
The Biology and Clinical Consequence of JC Virus Infection in the Human Brain---Progressive Multifocal Leukoenecephalopathy	205	(18)
Jean Hou
Peter N. Jensen
Eugene O. Major
Transmissible Spongiform Encephalopathies and Prion Protein	223	(13)
Bruce Chesebro
Alphavirus Encephalomyelitis: Determinants of Outcome	236	(13)
Diane E. Griffin
Andrew P. Byrnes
Macaque Models of the Neuropathogenesis of HIV Infection	249	(19)
Shilpa Buch
Sunil A. David
Paul D. Cheney
Ravis Raghavan
Opendra Narayan
Borna Disease Virus and the Brain	268	(21)
Juan Carlos de la Torre
Immunocytotherapy of Persistent Viral Infection	289	(7)
Dietmar P. Berger
Dirk Homann
Michael B.A. Oldstone
Class I Major Histocompatibility Molecules Play a Critical Role in Resistance to Theiler's Virus Infection	296	(21)
Aaron J. Johnson
Moses Rodriguez
Larry R. Pease
The Genetics of Multiple Sclerosis	317	(20)
Stephen L. Hauser
Lisa F. Barcellos
Jorge R. Oksenberg
Simple Genetic Models of Human Neurologic Disease	337	(24)
Mel B. Feany
Index	361