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9781620818169

New Developments in Chromatin Research

by
  • ISBN13:

    9781620818169

  • ISBN10:

    1620818167

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2012-11-01
  • Publisher: NOVA SCIENCE PUBLISHERS INC
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List Price: $150.00

Summary

Chromatin is DNA plus the proteins (and RNA) that package DNA within the cell nucleus. The primary functions of chromatin are: to package DNA into a smaller volume to fit in the cell, to strengthen the DNA to allow mitosis and meiosis and prevent DNA damage, and to control gene expression and DNA replication. In this book, the authors present topical research in the study of chromatin including the varied functions of aurora kinases A and B in mitosis and carcinogenesis; the chromatin state of pluripotent stem cells; MITF meets chromatin in melanoma; the state of chromatin as an integrative indicator of cell stress; analysing DNA damage and its repair throughout entire genomes; the cloning process, structural characterisation of Revolver transposon and its patented application for chromosome tags; DNA damage and Rad16; and glucocorticoid-induced chromatin remodelling.

Table of Contents

Preface
The Varied Functions of Aurora Kinases A & B in Mitosis & Carcinogenesis
New Developments in Chromatin Research: An Epigenetic Perspective
The Chromatin State of Pluripotent Stem Cells
MITF Meets Chromatin in Melanoma
The State of Chromatin as an Integrative Indicator of Cell Stress
A Genomics Approach to Analysing DNA Damage & its Repair throughout Entire Genomes
Recent Patent on Revolver-2: A Novel Transposon-Like Gene Useful for Chromosome Tags of Rye
Table of Contents provided by Publisher. All Rights Reserved.

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