Oncology

by Chang, Alfred E.; Ganz, Patricia A.; Hayes, Daniel F., M.D.; Kinsella, Timothy J.; Pass, Harvey I.

• ISBN13: 9780387242910
• ISBN10: 0387242910
• Format: Hardcover
• Copyright: 2005-11-22
• Publisher: Springer Verlag

Summary

Oncology: An Evidence-Based Approach is a textbook designed to reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.

Table of Contents

Foreword
Evidence-based approach to oncology	p. 3
Principles of chemotherapy	p. 14
Principles of radiation oncology	p. 41
Principles of surgical therapy in oncology	p. 58
Principles of targeted and biological therapies	p. 73
Biologic principles of hematopoietic stem cell transplantation	p. 91
Evaluation of tumor markers : an evidence-based guide for determination of clinical utility	p. 106
Design and analysis of oncology clinical trials	p. 112
Ethics of clinical oncology research	p. 127
Informatics infrastructure for evidence-based cancer medicine	p. 143
Economics of cancer care	p. 151
Principles of screening for cancer	p. 161
Patient decision making	p. 177
Establishing an interdisciplinary oncology team	p. 184
Principles of complementary and alternative medicine for cancer	p. 194
Fundamental aspects of the cell cycle and signal transduction	p. 207
Viral carcinogenesis	p. 214
Environmental carcinogenesis	p. 233
Cancer metastasis	p. 244
Tumor immunology and immunotherapy	p. 254
Technologies in molecular biology : diagnostic applications	p. 269
Cancer epidemiology	p. 287
Evidence-based cancer prevention research : a multidisciplinary perspective on cancer prevention trials	p. 301
Screening	p. 317
Genetic screening and counseling for high-risk populations	p. 341
Behavior modification	p. 358
Central nervous system imaging	p. 369
Breast imaging	p. 381
Imaging of thoracic malignancies	p. 392
Imaging of gastrointestinal stromal tumor	p. 413
Genitourinary imaging	p. 425
Musculoskeletal imaging	p. 442
Positron emission tomography and cancer	p. 449
Central nervous system tumors	p. 487
Eye, orbit, and adnexal structures	p. 506
Head and neck cancer	p. 528
Lung cancer	p. 545
Therapy for malignant pleural mesothelioma	p. 622
Mediastinum	p. 645
Esophageal cancer	p. 664
Stomach	p. 680
Colon, rectal, and anal cancer management	p. 704
Adenocarcinoma and other small intestinal malignancies	p. 733
Cancer of the liver and bile ducts	p. 745
An evidence-based approach to the management of pancreatic cancer	p. 764
Renal cell cancer	p. 782
Ureter, bladder, penis, and urethra	p. 806
Prostate cancer	p. 826
Testis cancer	p. 844
Cervix, vulva, and vagina	p. 874
Gestational trophoblastic neoplasia	p. 892
Ovarian cancer	p. 903
Uterine malignancies	p. 928
Evidence-based management of breast cancer	p. 951
Thyroid and parathyroid	p. 983
Tumors of the endocrine system	p. 1005
Sarcomas of bone	p. 1025
Soft tissue sarcoma	p. 1039
Cutaneous melanoma	p. 1073
Nonmelanoma cutaneous malignancies	p. 1093
Cancer of unknown primary site	p. 1110
Solid tumors of childhood	p. 1124
Acute myeloid leukemia and the myelodysplastic syndromes	p. 1151
Acute lymphoblastic leukemia	p. 1173
Chronic lymphocytic leukemia and related chronic leukemias	p. 1201
Chronic myeloid leukemia	p. 1220
An evidence-based approach to the management of Hodgkin's lymphoma	p. 1231
The non-Hodgkin's lymphomas	p. 1247
Multiple myeloma	p. 1276
Superior vena cava syndrome	p. 1291
Central nervous system emergencies	p. 1299
Metabolic emergencies in ontology	p. 1312
Surgical emergencies	p. 1323
Oral complications of cancer therapy	p. 1340
Alopecia and cutaneous complications of chemotherapy	p. 1354
Infectious complications of cancer therapy	p. 1363
Acute toxicities of therapy : pulmonary complications	p. 1401
Cardiac complications	p. 1411
Neurologic complications of therapy	p. 1418
Acute toxicities of therapy : urologic complications	p. 1426
Issues in vascular access with special emphasis on the cancer patient	p. 1434
Management of cancer pain	p. 1446
Nausea and vomiting in the cancer patient	p. 1473
Nutritional support for the cancer patient	p. 1488
Paraneoplastic syndromes	p. 1506
Malignant effusions	p. 1518
Evidence-based use of hematopoietic growth factors for optimal supportive care of patients with cancer	p. 1526
Management of the bone marrow transplant patient	p. 1536
Management of anxiety and depression in adult cancer patients : toward an evidence-based approach	p. 1552
Reproductive complications and sexual dysfunction in the cancer patient	p. 1580
The care of the terminal patient	p. 1601
Metastatic cancer to the central nervous system	p. 1612
Metastatic cancer to lung	p. 1626
Surgical and regional therapy for liver metastases	p. 1636
Metastatic cancer to bone	p. 1655
Cancer in the immunosuppressed patient	p. 1680
Cancer in the older population	p. 1708
Chemotherapy in patients with organ dysfunction	p. 1721
Management of the pregnant cancer patient	p. 1738
Survivorship research : past, present, and future	p. 1753
Late effects of cancer treatments	p. 1768
Medical and psychosocial issues in childhood cancer survivors	p. 1791
Medical and psychosocial issues in Hodgkin's disease survivors	p. 1804
Medical and psychosocial issues in testicular cancer survivors	p. 1815
Medical and psychosocial issues in gynecologic cancer survivors	p. 1828
Medical, psychosocial, and health-related quality of life issues in breast cancer survivors	p. 1836
Medical and psychosocial issues in prostate cancer survivors	p. 1859
Physical and psychosocial issues in lung cancer survivors	p. 1871
Cancer survivorship issues in colorectal cancer	p. 1891
Medical and psychosocial issues in transplant survivors	p. 1902
Second malignancies after radiation treatment and chemotherapy for primary cancers	p. 1929
Psychosocial rehabilitation in cancer care	p. 1942
Cancer advocacy	p. 1955
Table of Contents provided by Blackwell. All Rights Reserved.