Oncology Nursing Drug Handbook 2002

by Wilkes, Gail M.; Ingwersen, Karen; Barton-Burke, Margaret

• ISBN13: 9780763719906
• ISBN10: 0763719900
• Edition: Revised
• Format: Paperback
• Copyright: 2001-12-01
• Publisher: Jones & Bartlett Pub

Summary

Current knowledge of the drugs used in cancer care is critical for today's practicing nurse. Drugs covered are described in terms of their mechanism of action, metabolism, drug interactions, laboratory effects/interference, and special considerations. Potential toxicities, side effects, and the nursing process are detailed.

Table of Contents

Key to Abbreviations	p. xiii
Preface	p. xvii
Contributors	p. xix
Cancer Treatment	p. 1
Introduction to Chemotherapy Drugs	p. 2
Acridinyl anisidide	p. 31
Adrenocorticoids	p. 34
Altretamine	p. 38
9-aminocamptothecin	p. 40
Aminoglutethimide	p. 42
Anastrozole	p. 44
Androgens: testosterone propionate, obfluoxymesterone, obtestolactone	p. 46
Arsenic trioxide	p. 48
Asparaginase	p. 55
5-azacytidine	p. 58
Bicalutamide	p. 61
Bleomycin sulfate	p. 62
Busulfan	p. 65
Busulfan for injection	p. 67
Capecitabine	p. 74
Carboplatin	p. 77
Carmustine	p. 80
Chlorambucil	p. 84
Cisplatin	p. 86
Cladribine	p. 91
Cyclophosphamide	p. 95
Cytarabine, cytosine arabinoside	p. 99
Cytarabine liposome injection	p. 103
Dacarbazine	p. 105
Dactinomycin	p. 108
Daunorubicin citrate liposome injection	p. 111
Daunorubicin hydrochloride	p. 114
Decitabine	p. 117
Docetaxel	p. 119
Doxorubicin hydrochloride	p. 127
Doxorubicin hydrochloride liposome injection	p. 131
Eniluracil	p. 138
Epirubicin	p. 140
Estramustine	p. 145
Estrogens: diethylstilbestrol, ethinyl estradiol, conjugated estrogen, chlorotrianisene	p. 147
Etoposide	p. 150
Exemestane	p. 154
Floxuridine	p. 157
Fludarabine phosphate	p. 160
5-fluorouracil	p. 162
Flutamide	p. 164
Gemcitabine	p. 166
Goserelin acetate	p. 170
Hydroxyurea	p. 172
Idarubicin	p. 175
Idoxifene	p. 178
Ifosfamide	p. 180
Irinotecan	p. 183
Karenitecin	p. 192
Ketoconazole	p. 194
Letrozole	p. 197
Leuprolide acetate	p. 199
Lomustine	p. 202
Mechlorethamine hydrochloride	p. 204
Melphalan hydrochloride	p. 208
Menogaril	p. 211
Mercaptopurine	p. 213
Methotrexate	p. 215
Methyl-CCNU	p. 219
Mitomycin	p. 222
Mitotane	p. 225
Mitoxantrone	p. 226
Nilutamide	p. 229
Oxaliplatin	p. 231
Paclitaxel	p. 233
Pamidronate disodium	p. 240
Pegasparaginase	p. 242
Pentostatin	p. 245
Plicamycin	p. 249
Polifeprosan 20 with carmustine (BCNU) implant	p. 252
Procarbazine hydrochloride	p. 255
Progestational Agents: medroxyprogesterone acetate, megestrol acetate	p. 258
Raloxifene hydrochloride	p. 259
Raltitrexed	p. 262
Rebeccamycin analogue	p. 265
Rubitecan	p. 267
Streptozocin	p. 270
Tamoxifen citrate	p. 272
Temozolamide	p. 275
Teniposide	p. 278
Thioguanine	p. 281
Thiotepa	p. 283
Topotecan hydrochloride for injection	p. 285
Toremifene citrate	p. 288
Trimetrexate	p. 289
UFT	p. 292
UFT plus leucovorin	p. 294
Valrubicin	p. 296
Vinblastine	p. 298
Vincristine	p. 301
Vindesine	p. 304
Vinorelbine tartrate	p. 306
Biologic Response Modifier Therapy	p. 311
Epoetin alfa	p. 315
Filgrastim	p. 317
Interferon alfa-2a	p. 319
Interferon alfa-2b	p. 323
Interferon gamma	p. 327
Interleukin-2	p. 330
Interleukin-3	p. 334
Interleukin-6	p. 335
Interleukin-12	p. 337
Levamisole hydrochloride	p. 339
Megakaryocyte growth and development factor	p. 342
Novel erythropoiesis stimulating factor	p. 343
Oprelvekin	p. 344
PIXY-321	p. 347
Sargramostim	p. 348
Tumor necrosis factor	p. 351
Antineoplastic Treatment Agonists: Radiosensitizers, Chemosensitizers, and Chemical Adjuncts	p. 354
Chromic phosphate P32 suspension	p. 355
Etanidazole	p. 358
Fluosol DA (20%)	p. 395
Leucovorin calcium	p. 360
Porfirmer	p. 362
Tirapazamine	p. 364
Cytoprotective Agents	p. 367
Allopurinol sodium	p. 371
Amifostine for injection	p. 374
BNP7787	p. 377
Dexrazoxane for injection	p. 379
Glutamine	p. 380
Mesna for injection	p. 382
Molecularly Targeted Therapies	p. 384
AG3340	p. 409
Campath-1H	p. 411
Altretinoin gel 0.1%	p. 414
Arasentan	p. 416
Bevacizumab	p. 417
Bexarotene	p. 420
Cetuximab	p. 426
Denileukin diftitox	p. 429
Erlotinib	p. 435
Gemtuzumab ozogamicin for injection	p. 438
[superscript 90]Y ibritumomab tiuxetan	p. 442
Imatinib mesylate	p. 444
Neovastat	p. 449
Rituximab	p. 450
Thalidomide	p. 454
Tositumomab, I[superscript 131]	p. 456
Trastuzumab	p. 460
Tretinoin	p. 463
Liposomal tretinoin	p. 466
ZD1839	p. 471
Symptom Management	p. 473
Pain	p. 474
Non-narcotic Analgesics	p. 482
Acetaminophen	p. 482
Aspirin, acetylsalicylic acid	p. 483
Celecoxib	p. 486
Choline magnesium trisalicylate	p. 489
Clonidine hydrochloride	p. 491
Gabapentin	p. 493
Ibuprofen	p. 497
Indomethacin	p. 500
Ketorolac tromethamine	p. 503
Rofecoxib	p. 507
Salsalate	p. 510
Narcotic Analgesics	p. 513
Codeine	p. 513
Fentanyl citrate	p. 516
Fentanyl transdermal system	p. 520
Hydromorphone	p. 524
Levorphanol tartrate opioid	p. 528
Meperidine hydrochloride	p. 531
Methadone	p. 536
Morphine	p. 540
Morphine-dextromethorphan	p. 544
Oxycodone	p. 547
Nausea and Vomiting	p. 552
Dexamethasone	p. 559
Diphenhydramine hydrochloride	p. 561
Dolasetron mesylate	p. 563
Dronabinol	p. 566
Droperidol	p. 567
Granisetron hydrochloride	p. 569
Haloperidol	p. 570
Metoclopramide hydrochloride	p. 572
Ondansetron hydrochloride	p. 574
Perphenazine	p. 575
Prochlorperazine	p. 577
Promethazine hydrochloride	p. 579
Scopolamine	p. 580
Thiethylperazine	p. 581
Anorexia and Cachexia	p. 583
Dronabinol	p. 585
Megestrol acetate	p. 586
Thalidomide	p. 588
Anxiety and Depression	p. 592
Alprazolam	p. 593
Amitriptyline hydrochloride	p. 596
Bupropion hydrochloride	p. 598
Buspirone hydrochloride	p. 602
Citalopram hydrobromide	p. 603
Clonazepam	p. 607
Desipramine hydrochloride	p. 610
Diazepam	p. 613
Doxepin hydrochloride	p. 616
Fluoxetine hydrochloride	p. 618
Imipramine pamoate	p. 622
Lorazepam	p. 625
Mirtazapine	p. 628
Nefazodone HCl	p. 631
Nortriptyline hydrochloride	p. 634
Oxazepam	p. 637
Paroxetine hydrochloride	p. 640
Sertraline hydrochloride	p. 643
Trazodone hydrochloride	p. 645
Venlafaxine hydrochloride	p. 648
Zolpidem tartrate	p. 652
Complications	p. 655
Hypercalcemia	p. 656
Calcitonin-salmon	p. 659
Etidronate disodium	p. 661
Furosemide	p. 663
Gallium nitrate	p. 665
Pamidronate disodium	p. 667
Zolendronate	p. 669
Infection	p. 672
Antibiotics	p. 679
Amikacin sulfate	p. 679
Amoxicillin	p. 683
Ampicillin	p. 686
Azithromycin	p. 689
Aztreonam	p. 692
Carbenicillin indanyl sodium	p. 695
Cefaclor	p. 698
Cefamandole nafate	p. 701
Cefazolin sodium	p. 704
Cefdinir	p. 708
Cefepime	p. 711
Cefixime	p. 714
Cefoperazone sodium	p. 717
Cefotaxime sodium	p. 720
Cefoxitin sodium	p. 723
Cefpodoxime proxetil	p. 727
Cefprozil	p. 728
Ceftazidime	p. 730
Ceftibuten	p. 734
Ceftriaxone sodium	p. 736
Cephradine	p. 739
Ciprofloxacin	p. 743
Clindamycin phosphate	p. 746
Co-trimoxazole; trimethoprim and sulfamethoxazole	p. 748
Dicloxacillin sodium	p. 752
Doxycycline hyclate	p. 755
Erythromycin	p. 758
Gatifloxacin	p. 762
Gentamicin sulfate	p. 765
Imipenem/cilastatin sodium	p. 768
Kanamycin sulfate	p. 772
Levofloxacin	p. 775
Linezolid	p. 779
Metronidazole hydrochloride	p. 781
Mezlocillin sodium	p. 784
Minocycline hydrochloride	p. 788
Nafcillin sodium	p. 791
Oxacillin sodium	p. 794
Penicillin G	p. 797
Piperacillin sodium	p. 801
Quinupristin and dalfopristin	p. 805
Streptomycin sulfate	p. 807
Ticarcillin disodium	p. 811
Tobramycin sulfate	p. 815
Vancomycin hydrochloride	p. 818
Antifungals	p. 822
Amphotericin B; amphotericin B lipid complex	p. 822
Caspofungin	p. 826
Fluconazole	p. 828
Flucytosine	p. 831
Itraconazole	p. 833
Ketoconazole	p. 835
Miconazole nitrate	p. 838
Nystatin	p. 840
Antivirals	p. 842
Acyclovir	p. 842
Cidofovir	p. 845
Famiclovir	p. 848
Foscarnet sodium	p. 850
Ganciclovir	p. 853
Valacyclovir hydrochloride	p. 857
Constipation	p. 858
Bisacodyl	p. 859
Docusate calcium, docusate potassium, docusate sodium	p. 860
Glycerin suppository	p. 861
Lactulose	p. 863
Magnesium citrate	p. 864
Methylcellulose	p. 865
Mineral oil	p. 866
Polyethylene glycol 3350, NF powder	p. 868
Senna	p. 869
Sorbitol	p. 871
Diarrhea	p. 873
Deodorized tincture of opium	p. 874
Diphenoxylate hydrochloride and atropine	p. 875
Kaolin/pectin	p. 877
Loperamide hydrochloride	p. 878
Octreotide acetate	p. 879
Polypharmacy	p. 883
Polypharmacy	p. 884
Controlling Occupational Exposure to Hazardous Drugs	p. 890
National Cancer Institute Common Toxicity Criteria	p. 920
Cancer Chemotherapeutic Regimes (Adult)	p. 975
Index	p. 1025
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