CART

(0) items

Organic Synthesis : The Disconnection Approach

by ;
Edition:
2nd
ISBN13:

9780470712368

ISBN10:
0470712368
Format:
Paperback
Pub. Date:
12/31/2008
Publisher(s):
Wiley
List Price: $53.33

Rent Textbook

(Recommended)
 
Term
Due
Price
$32.00

Buy New Textbook

Currently Available, Usually Ships in 24-48 Hours
N9780470712368
$51.66

Used Textbook

We're Sorry
Sold Out

eTextbook

We're Sorry
Not Available

More New and Used
from Private Sellers
Starting at $37.91
See Prices

Questions About This Book?

Why should I rent this book?
Renting is easy, fast, and cheap! Renting from eCampus.com can save you hundreds of dollars compared to the cost of new or used books each semester. At the end of the semester, simply ship the book back to us with a free UPS shipping label! No need to worry about selling it back.
How do rental returns work?
Returning books is as easy as possible. As your rental due date approaches, we will email you several courtesy reminders. When you are ready to return, you can print a free UPS shipping label from our website at any time. Then, just return the book to your UPS driver or any staffed UPS location. You can even use the same box we shipped it in!
What version or edition is this?
This is the 2nd edition with a publication date of 12/31/2008.
What is included with this book?
  • The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any CDs, lab manuals, study guides, etc.
  • The Rental copy of this book is not guaranteed to include any supplemental materials. You may receive a brand new copy, but typically, only the book itself.

Summary

Organic Synthesis: The Disconnection Approach is the long-awaited second edition of a classic textbook; the first to provide a structured course in retrosynthesis- now an important technique used by generations of organic chemists. Now fully revised and updated with a modern look, 25 years of advances in organic synthesis are reflected with the addition of new examples and synthetic pathways. Additional material has been added to take the student to the level required by the bestselling sequel, "Organic Synthesis: Strategy and Control" and the later chapters have extensive new material based on courses that the authors give to chemists in the pharmaceutical industry.

Table of Contents

Prefacep. ix
General Referencesp. xi
The Disconnection Approachp. 1
Basic Principles: Synthons and Reagents Synthesis of Aromatic Compoundsp. 7
Strategy I: The Order of Eventsp. 17
One-Group C-X Disconnectionsp. 23
Strategy II: Chemoselectivityp. 29
Two-Group C-X Disconnectionsp. 35
Strategy III: Reversal of Polarity, Cyclisations, Summary of Strategyp. 45
Amine Synthesisp. 53
Strategy IV: Protecting Groupsp. 61
One Group C-C Disconnections I: Alcoholsp. 69
General Strategy A: Choosing a Disconnectionp. 77
Strategy V: Stereoselectivity Ap. 83
One Group C-C Disconnections II: Carbonyl Compoundsp. 93
Strategy VI: Regioselectivityp. 101
Alkene Synthesisp. 107
Strategy VII: Use of Acetylenes (Alkynes)p. 115
Two-Group C-C Disconnections I: Diels-Alder Reactionsp. 121
Strategy VIII: Introduction to Carbonyl Condensationsp. 129
Two-Group C-C Disconnections II: 1,3-Difunctionalised Compoundsp. 133
Strategy IX: Control in Carbonyl Condensationsp. 139
Two-Group C-C Disconnections III: 1,5-Difunctionalised Compounds Conjugate (Michael) Addition and Robinson Annelationp. 151
Strategy X: Aliphatic Nitro Compounds in Synthesisp. 161
Two-Group Disconnections IV: 1,2-Difunctionalised Compoundsp. 167
Strategy XI: Radical Reactions in Synthesisp. 177
Two-Group Disconnections V: 1,4-Difunctionalised Compoundsp. 185
Strategy XII: Reconnectionp. 193
Two-Group C-C Disconnections VI: 1,6-diCarbonyl Compoundsp. 199
General Strategy B: Strategy of Carbonyl Disconnectionsp. 207
Strategy XIII: Introduction to Ring Synthesis: Saturated Heterocyclesp. 217
Three-Membered Ringsp. 229
Strategy XIV: Rearrangements in Synthesisp. 237
Four-Membered Rings: Photochemistry in Synthesisp. 245
Strategy XV: The Use of Ketenes in Synthesisp. 251
Five-Membered Ringsp. 255
Strategy XVI: Pericyclic Reactions in Synthesis: Special Methods for Five-Membered Ringsp. 261
Six-Membered Ringsp. 269
General Strategy C: Strategy of Ring Synthesisp. 279
Strategy XVII: Stereoselectivity Bp. 289
Aromatic Heterocyclesp. 301
General Strategy D: Advanced Strategyp. 313
Indexp. 325
Table of Contents provided by Ingram. All Rights Reserved.


Please wait while the item is added to your cart...