The Overlap of Affective and Schizophrenic Spectra

by Edited by Andreas Marneros , Hagop S. Akiskal

• ISBN13: 9780521858588
• ISBN10: 0521858585
• Edition: 1st
• Format: Hardcover
• Copyright: 2006-12-11
• Publisher: Cambridge University Press

Summary

Many clinicians and researchers are convinced that there is an overlap between affective and schizophrenic spectra. In this book, an international team of experts discuss aspects of comorbidity, genetic models, clinical course, phenomenology and therapies. This is the first comprehensive overview of the schizoaffective spectra. Challenging cases presenting clinical and paraclinical features of both spectra are surprisingly numerous. Not only the phenomenology but also the course, outcome and treatment of such cases have their own characteristics. Recent research shows that the overlap also involves genetics and biological processes related to psychotic disorders. Within the overlap of affective and schizophrenic spectra it is possible to identify some groups of disorders having similar clinical and non-clinical features: the 'schizoaffective' group, 'Acute and Transient Psychotic Disorder' or 'Brief Psychosis', and other groups found in so-called 'Atypical Forms'.

Author Biography

Andreas Marneros is Professor of Psychiatry in the Department of Psychiatry and Psychotherapy at the Martin-Luther-Universitat in Halle-Wittenberg, Germany Hagop Akiskal is Professor of Psychiatry and Director of the International Mood Center at the University of California at San Diego

Table of Contents

List of contributors	vii
Preface	xi
1 The paradigma of overlapping affective and schizophrenic spectra: schizoaffective conditions	1
Andreas Marneros
2 The overlapping of the spectra: overlapping genes and genetic models	25
John R. Kelsoe
3 The continuum of psychosis and its genetic basis	43
T.J. Crow
4 Functional psychoses: molecular-genetic evidence for a continuum	55
Hans H. Stassen, Christian Scharfetter and Jules Angst
5 State- and trait-related deficits in sustained attention in bipolar disorder: are there any overlaps with schizophrenia?	79
Luke Clark
6 The concept of schizoaffective disorder: utility versus validity and reliability – a transcultural perspective	104
Ahmed Okasha
7 Phenomenological approaches to the schizoaffective spectrum	133
William Coryell
8 Clinical course of schizoaffective disorders	145
Maria Reinares, Eduard Vieta, Antoni Benabarre and Andreas Marneros
9 Depressive syndromes in schizophrenia	156
Wolfgang Gaebel, Ellen Bittner and Wolfgang Wölwer
10 The overlapping of the spectra: brief and acute psychoses	182
Frank Pillmann and Andreas Marneros
11 Overlapping of the spectra: physical comorbidity between schizophrenia and affective disorders	207
William S. Stone, Andrea H. Roe and Ming T. Tsuang
12 The overlapping of the spectra suicide	224
Simavi Vahip
13 Biological treatment of schizoaffective disorders	248
Christopher Baethge
14 Psychological therapies and schizoaffective disorders	264
Jan Scott
Epilogue: The interface of affective and schizophrenic disorders: a cross between two spectra?	277
Hagop S. Akiskal
Index	293