Oxford Handbook of Auditory Science The Ear

by Fuchs, Paul

• ISBN13: 9780199233397
• ISBN10: 019923339X
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-03-12
• Publisher: Oxford University Press

Summary

The first volume in the Oxford Handbook of Auditory Science, The Ear serves both as an introduction and as a reference work for anyone interested in the auditory periphery. Each chapter includes a mix of tutorial and advanced information. Throughout the book, the focus is on mechanistic, functional evidence, with many chapters concentrating on cellular and molecular explanations of cochlear function. In addition to basic function, the development and regeneration of the inner ear are described, as are the growing body of ear-related genes identified through studies of human deafness and animal mutants. This knowledge is applied to the human condition in descriptions of pathogenic mechanisms, and existing therapies, especially the cochlear implant.

Whether the reader is a student entering the field, a clinical practitioner, or a worker in an allied field of study, this volume will be a valuable resource of basic information, and perhaps a catalyst to making their own contributions to the ongoing challenge, and adventure, of understanding the mysteries of the ear.

Author Biography

1974 BA in Biology, Reed College, Portland Oregon. Ph.D. in Neuroscience, Stanford University, 1979. Postdoctoral fellow with J.G. Nicholls, Stanford, 1979-1981. Postdoctoral fellow with R. Fettiplace, Cambridge University, 1981-1984. Assistant Professor of Physiology, University of Colorado Health Sciences Center, 1984-1990. Associate Professor of Physiology, University of Colorado Health Sciences Center, 1990-1995. Professor of Otolaryngology- Head and Neck Surgery, Johns Hopkins University School of Medicine, 1995-date. Professor of Biomedical Engineering, Johns Hopkins University School of Medicine, 1995-date. Professor of Neuroscience, Johns Hopkins University School of Medicine, 1999-date. Director of Research and John E. Bordley Professor of Otolaryngology-Head and Neck Surgery, 2005-date. Board of Scientific Counselors, the National Institute for Deafness and Communication Disorders, NIH, 2003-2008.

Table of Contents

Introduction and overview

The clinical cochlea

External and middle ear function

Otoascoustic emissions and evoked potentials

Cochlear mechanics, tuning, non-linearities

Electromotility of outer hair cells

Inner ear fluid homeostatis

Hair bundle structure and mechanotransduction

The afferent synapse

Efferent innervation and function

Cochlear supporting cells

Development of the inner ear

Regeneration of the cochlea

Genetics of hearing loss

Hearing aids and cochlear implants

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