9780135564158

Summary

DIGITAL UPDATE available for Fall 2021 classes

Engage students with real-world applications of genetics
Informed by more than 50 years of experience and experimentation in teaching genetics, authors Mark Sanders and John Bowman share their excitement about genetics and the dynamism at work in the field with Genetic Analysis: An Integrated Approach. The authors use an integrated approach to help contextualize three core challenges of learning genetics: solving problems, understanding the connection between traditional genetics models and more modern approaches, and understanding evolution.

With the 3rd Edition, the authors provide students with additional problem solving guidance and a new emphasis on real-world applications of genetics. They also strive to make learning the details of genetics easier and offer ways to facilitate group work and discussion of genetics problems and concepts. The revision incorporates key updates that keep pace with changes in the field, such as advances in CRISPR-Cas, more discussion of epigenetics and expanded coverage of genomic approaches.

For all introductory genetics courses.

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Author Biography

Mark F. Sanders has been a faculty member in the Department of Molecular and Cellular Biology at the University of California, Davis, since 1985. In that time, he has taught more than 150 genetics courses to nearly 35,000 undergraduate students. Although he specializes in teaching the genetics course for which this book is written, his genetics teaching experience also includes a genetics laboratory course, an advanced human genetics course for biology majors, and a human heredity course for nonscience majors, as well as introductory biology and courses in population genetics and evolution. He has also served as an advisor to undergraduate students and in undergraduate education administration, and he has directed several undergraduate education programs.

Dr. Sanders received his B.A. degree in Anthropology from San Francisco State University, his M.A. and Ph.D. degrees in Biological Anthropology from the University of California, Los Angeles, and 4 years of training as a postdoctoral researcher studying inherited susceptibility to human breast and ovarian cancer at the University of California, Berkeley.

John L. Bowman is a professor in the School of Biological Sciences at Monash University in Melbourne, Australia, and an adjunct professor in the Department of Plant Biology at the University of California, Davis, in the United States. He received a B.S. in Biochemistry at the University of Illinois at Urbana-Champaign in 1986 and a Ph.D. in Biology from the California Institute of Technology in Pasadena, California. His Ph.D. research focused on how the identities of floral organs are specified in Arabidopsis (described in Chapter 18), and he conducted postdoctoral research at Monash University on the regulation of floral development. From 1996 to 2006, his laboratory at UC Davis investigated developmental genetics of plants, focusing on how leaves are patterned. From 2006 to 2011, he was a Federation Fellow at Monash University, where his laboratory is studying land plant evolution using a developmental genetics approach. He was elected a Fellow of the Australian Academy of Science in 2014. At UC Davis he taught genetics, “from Mendel to cancer,” to undergraduate students, and he continues to teach genetics courses at Monash University.

1. The Molecular Basis of Heredity, Variation, and Evolution

2. Transmission Genetics

3. Cell Division and Chromosome Heredity

4. Inheritance Patterns of Single Genes and Gene Interaction

5. Genetic Linkage and Mapping in Eukaryotes

6. Genetic Analysis and Mapping in Bacteria and Bacteriophage

Application Chapter: Part I: Genetic Counseling

7. DNA Structure and Replication

8. Molecular Biology of Transcription and RNA Processing

9. The Molecular Biology of Translation

Application Chapter: Part II: Genetic Testing

10. Chromosome Chapter Title TBD

11. Gene Mutation, DNA Repair, and Homologous Recombination

12. Chromosome Chapter Title TBD

13. Regulation of Gene Expression in Bacteria and Bacteriophage

14. Regulation of Gene Expression in Eukaryotes

15. Analysis of Gene Function by Forward Genetics and Reverse Genetics

Application Chapter: Part III: Cancer Genetics

16. Recombinant DNA Technology and Its Applications

17. Genomics: Genetics from a Whole-Genome Perspective

18. Organelle Inheritance and the Evolution of Organelle Genomes

19. Developmental Genetics

20. Genetic Analysis of Quantitative Traits

Application Chapter: IV: Personalized Medicine

21. Population Genetics and Evolution at the Population, Species, and Molecular Levels

Application Chapter: V: Forensic Genetics

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