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9781405124072

Pediatric Solid Organ Transplantation

by ; ; ; ;
  • ISBN13:

    9781405124072

  • ISBN10:

    1405124075

  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 2007-02-12
  • Publisher: Wiley-Blackwell
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Summary

Pediatric Solid Organ Transplantation is a comprehensive and succinct text on all aspects of pediatric solid organ transplantation. It provides a ready source of reference, to both the basic science and organ specific surgical technique and after care. This second edition has been extensively updated in light of recent developments in this rapidly advancing area. The only textbook devoted to the field of pediatric transplantation bull; bull;A definitive reference for all those interested in improving the care and quality of life of children undergoing solid organ transplantation bull;Section on immunosuppression has been expanded by four chapters to include sections on; - mechanisms of action - therapies for the sensitized patient - post-transplant lymphoproliferative disorders - organ toxicities of immunosuppressive therapy bull;A new section has been added on the many topics related to quality of life that effect survivors of pediatric transplantation bull;International editorial and contributor team represents a wide geographical range and contains both recognized leaders and emerging experts Whether you are an established sub-specialist in pediatric transplantation, a transplant surgeon, or a pediatric specialist in a related area, this book will answer all your questions about care of the pediatric patient before, during, and after transplantation.

Author Biography

Professor Richard Fine, Professor and Chairman, Department of Paediatrics, State University of New York, USA

Dr Steve Webber, Division of Cardiology, Children's Hospital of Pittsburgh, USA

Dr William Harman, Associate Professor of Paediatrics, Harvard Medical School, Boston, USA

Table of Contents

Preface
Contributors
Immunology and Genetics
The Immune Response to Organ Allografts
Allorecognition Pathways
Costimulation
The HLA System and Histocompatibility Testing for Organ Transplantation
Gene Polymorphisms and Pharmacogenomics
Genomics and Proteomics as Research Tools
Tolerance: A Review of its Mechanisms in the Transplant Setting
Immunosuppression and its Complications
Mechanism of Action of Immunosuppressive Agents
Induction and Maintenance Immunosuppression
Novel Immunosuppressants
Therapies for Allosensitized Patient
Infections Post-transplantation
Post-transplant Lymphoproliferative Disorders and Malignancy
Organ Toxicities
Kidney Transplantation
Historical Notes
Recipient Characteristics
Evaluation of the Candidate
Donor Evaluation, Surgical Technique and Perioperative Management
Pathology of the Kidney Allograft
Post-transplant Management
Outcome and Risk Factors
Liver Transplantation
Historical Notes
Recipient Characteristics
Evaluation of the Candidate
Donor Evaluation, Surgical Techniques and Perioperative Management
Pathology of the Liver Allograft
Post-transplant Management
Outcome and Risk Factors
Heart Transplantation
Historical Notes
Recipient Characteristics
Evaluation of the Candidate
Donor Evaluation, Surgical Technique and Perioperative Management
Pathology of the Cardiac Allograft
Post-transplant Management
Outcomes and Risk Factors
Lung and Heart-Lung Transplantation
Historical Notes
Recipient Characteristics
Evaluation of the Candidtae for Heart and Lung Transplantation
Donor Evaluation, Surgical Technique and Perioperative Management
Pathology of Lung Allograft
Post-transplant Management
Outcomes and Risk Factors
Intestinal Transplantation
Historical Notes
Recipient Characteristics
Evaluation of the Candidate
Donor Evaluation, Surgical Technique and Perioperative Management
Pathology of the Intestinal Allograft
Post-transplant Managment
Outcomes and Risk Factors
Special Issues after Pediatric Transplantation
Growth and Puberty
Cognitive Development
Psychosocial Adaptation and Adherence
Pregnancy
Gynecologic Issues
Transition to Adult care
Index
Table of Contents provided by Publisher. All Rights Reserved.

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