Pharmacology Primer : Theory, Application and Methods

by Kenakin

• ISBN13: 9780124041615
• ISBN10: 0124041612
• Format: Paperback
• Copyright: 2003-12-19
• Publisher: Elsevier Science & Technology

Summary

Pharmaceutical companies continue to face a growing need for scientists trained in the basics of pharmacology. At GlaxoSmithKline, a pharmaceuticals world-leader, Terry Kenakin regularly teaches this course and has drawn on his valuable experience to write A Pharmacology Primer. This guide has been designed especially for scientists trained in molecular biology and related fields who now need to know the basic theories, principles and practical applications of pharmacology. Important chapters cover: Drug Receptor Theory; Drug Antagonism; The Drug Discovery Process; Pharmacological Assay Formats; Statistics & Experimental Design; and many more! A Pharmacology Primer is stocked with helpful resources -- derivations of all formulae in every chapter, a glossary and appendices, scores of full-color illustrations -- that further enhance the value and utility of this book. * 185 illustrations and figures, four-color throughout * Bulleted lists at the end of each section sum up main topics * Glossary of Pharmacological Terms included for quick reference

Table of Contents

Foreword
What Is Pharmacology?	p. 1
How Different Tissues Process Drug Response	p. 17
Drug Receptor Theory	p. 37
Pharmacological Assay Formats: Binding	p. 53
Agonists: The Measurement of Affinity and Efficacy in Functional Assays	p. 73
Drug Antagonism	p. 93
The Drug Discovery Process: System-Independent Scales of Drug Activity	p. 123
Statistics and Experimental Design	p. 147
Selected Pharmacological Methods	p. 177
Glossary of Pharmacological Terms	p. 195
Appendices	p. 201
Index	p. 211
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