Phasing in Crystallography A Modern Perspective

by Giacovazzo, Carmelo

• ISBN13: 9780199686995
• ISBN10: 0199686998
• Format: Hardcover
• Copyright: 2014-02-05
• Publisher: Oxford University Press

Author Biography

Carmelo Giacovazzo, Professor of Crystallography, Bari University; Istituto di Cristallografia, CNR Bari, Italy

Carmelo Giacovazzo, Professor of Crystallography, Bari University. Director of CNR - IC Institute from 1992 to 2008. President of the European Crystallographic Association from 1997 to 2000. Winner of the European Prize Italgas 1996 for Scientific Research and Innovation; European Crystallographic Association Prize 2003. Editor of the international reviews: Zeitschrift fur Kristallographie and Croatica Chemica Acta. Scientific research: about 300 scientific papers on phasing methods, oriented both to small and to macromolecules. Some of his contributions were quoted in the Nobel Lecture by Herbert Hauptman (1985) as relevant for the solution of the phase problem for small molecules.
His theoretical developments allowed to extend to about 2A the limit of the ab initio crystal structure solution of proteins, and allowed a powerful combination of traditional molecular replacement, isomorphous replacement and anomalous dispersion techniques with suitably designed probabilistic approaches.