Practical Transfusion Medicine, 2nd Edition

by Editor: Michael F. Murphy (Worldwide Clinical Trials, Atlanta, Georgia, and London, UK); Editor: Derwood H. Pamphilon (Institute of Transfusion Sciences and Royal Hospital for Sick Children, Bristol); Foreword by: David Weatherall

• ISBN13: 9781405118446
• ISBN10: 140511844X
• Edition: 2nd
• Format: Hardcover
• Copyright: 2005-08-01
• Publisher: Wiley-Blackwell

Summary

Essential practical manual for all those working in modern transfusion medicine Why Buy This Book?--Concise and 'user friendly' guide to transfusion medicine-Provides guidance for everyday clinical questions-Revised and updated throughout to reflect rapid developing areas-Scope broadened by including experts from the USAThis comprehensive guide to transfusion medicine has a practical and didactic approach. The text is divided into five main sections. The first deals with the basic principles of transfusion, and includes the background science of the blood group system and immunity. The second section deals with the use of transfusion in the range of clinical settings and this is followed by a section on the complications of transfusion and their management. The fourth section covers the organisational issues related to transfusion practice from donors and blood collection to medico-legal aspects. The final section takes a look at the future developments in the field and the implications for transfusion practice.This book is ideal for trainee haematologists revising for exams and as a reference book by clinical haematology staff faced with specific problems.

Author Biography

Michael F. Murphy, Consultant Haematologist, Deptartment of Haematology, The John Radcliffe Hospital, Oxford, UK

Derwood H. Pamphilon, Consultant Haematologist, Institute for Transfusion Sciences, Bristol, UK

Table of Contents

List of Contributors	p. vii
Foreword	p. xi
Preface to the second edition	p. xiii
Preface to the first edition	p. xv
Basic principles of transfusion
Introduction	p. 3
Essential immunology for transfusion medicine	p. 13
Human blood group systems	p. 24
Human leucocyte antigens	p. 34
Platelet and neutrophil antigens	p. 50
Clinical transfusion practice
The effective and safe use of blood components	p. 67
Bleeding associated with trauma and surgery	p. 86
Prenatal and childhood transfusions	p. 97
Haematological disease	p. 119
Transfusion strategies in organ transplant patients	p. 132
Inherited and acquired coagulation disorders	p. 138
Uses of intravenous immunoglobulin	p. 151
Complications of transfusion
Haemolytic transfusion reactions	p. 161
Febrile reactions and transfusion-related acute lung injury	p. 171
Urticarial and anaphylactic reactions	p. 179
Bacterial contamination	p. 184
Post-transfusion purpura	p. 191
Immunomodulation and graft-versus host disease	p. 195
Transfusion-transmitted infections	p. 208
Variant Creutzfeldt-Jakob disease	p. 229
Practice in blood centres and hospitals
Donors and blood collection	p. 241
Blood donation testing and the safety of the blood supply	p. 250
Production and storage of blood components	p. 259
Medicolegal aspects	p. 274
Blood transfusion in hospitals	p. 280
Autologous transfusion	p. 298
Tissue banking	p. 309
Cord blood banking	p. 320
Therapeutic apheresis	p. 328
Developments in transfusion medicine
Blood substitutes	p. 341
Cytokines in transfusion practice	p. 350
Haemopoietic stem cell processing and storage	p. 357
Haemopoietic stem cell transplantation and immunotherapy	p. 369
Gene therapy	p. 390
Recombinant antibodies and other proteins	p. 403
Blood transfusion in a global context	p. 415
The design of interventional trials in transfusion medicine	p. 424
Getting the most out of the evidence for transfusion medicine	p. 436
The future of transfusion medicine	p. 445
Index	p. 457
Table of Contents provided by Ingram. All Rights Reserved.