Practical Transfusion Medicine, 3rd Edition

by Michael F. Murphy (John Radcliffe Hospital, University of Oxford, UK ); Derwood H. Pamphilon (Institute of Transfusion Sciences and Royal Hospital for Sick Children, Bristol)

• ISBN13: 9781444311754
• ISBN10: 1444311751
• Format: eBook
• Copyright: 2009-04-01
• Publisher: Wiley-Blackwell

Summary

This new edition of the comprehensive guide to transfusion medicine is now fully revised and updated. The Third Edition includes two new sections, one on alternatives to blood transfusion, and one on cellular and tissues therapy and organ transplantation. It focuses on clinical aspects but also covers background science and organizational issues. This timely volume highlights controversial issues and provides advice for everyday clinical questions in transfusion medicine. Practical Transfusion Medicine, Third Edition, is an essential manual for all those working in modern transfusion medicine.

Table of Contents

Contributors

Foreword

Preface to the third edition

Preface to the first edition

Introduction: recent evolution of transfusion medicine

Basic principles of immunohaematology.

Essential immunology for transfusion medicine

Human blood group systems

Human leucocyte antigens

Platelet and neutrophil antigens

Complications of transfusion.

Investigation of acute transfusion reactions

Haemolytic transfusion reactions

Febrile and allergic transfusion reactions

Transfusion-related acute lung injury

Transfusion-related immunomodulation

Transfusion-associated graft-versus-host disease and microchimerism

Post-tranfusion purpura

Tranfusion-transmitted infections

Bacterial contamination

Variant Creutzfeldt-Jakob disease

Emerging infections and transfusion safety

Practice in blood centres and hospitals.

Regulatory aspects of blood transfusion

The role of haemovigilance in transfusion safety

Donors and blood collection

Blood donation testing and the safety of the blood supply

Production and storage of blood components

Medicolegal aspects of transfusion practice

Blood transfusion in hospitals

Blood transfusion in a global context

Clinical transfusion practice.

Good blood management: the effective and safe use of blood components

Prenatal and childhood transfusions

Haematological disease

Blood transfusion in the management of patients with haemoglobinopathies

Massive blood loss

Inherited and acquired coagulation disorders

Recombinant proteins in diagnosis and therapy

Immunodeficiency and immunoglobulin therapy

Alternatives to transfusion.

The principles of bloodless medicine and surgery

Autologous transfusion

Blood substitutes

Pharmacological agents and recombinant factor VIIa

Cellular and tissues therapy and organ transplantation.

Regulation and accreditation in cellular therapy

Stem cell collection and therapeutic apheresis

Haemopoietic stem cell processing and storage

Haemopoietic stem cell transplantation

Cord blood transplantation

Recent advances in clinical cellular immunotherapy

Cytokines in transfusion practice

Tissue banking

Transfusion strategies in organ transplant patients

Development of the evidence base for transfusion.

The design of interventional trials in transfusion medicine

Getting the most out of the evidence for transfusion medicine

How to influence clinicians' use of blood - improving the transfusion practice in hospitals?

Scanning the future of transfusion medicine

Index

Colour plates can be found facing page

Table of Contents provided by Publisher. All Rights Reserved.