Practical Transfusion Medicine

by Murphy, Michael F.; Pamphilon, Derwood H.

• ISBN13: 9781405181969
• ISBN10: 1405181966
• Edition: 3rd
• Format: Hardcover
• Copyright: 2009-04-27
• Publisher: Wiley-Blackwell

Summary

This new edition of the comprehensive guide to transfusion medicine is now fully revised and updated. The Third Edition includes two new sections, one on alternatives to blood transfusion, and one on cellular and tissues therapy and organ transplantation. It focuses on clinical aspects but also covers background science and organizational issues. This timely volume highlights controversial issues and provides advice for everyday clinical questions in transfusion medicine. Practical Transfusion Medicine, Third Edition, is an essential manual for all those working in modern transfusion medicine.

Author Biography

Michael F. Murphy MD, FRCP, FRCPath
Professor of Blood Transfusion Medicine, University of Oxford
Consultant Haematologist, NHS Blood & Transplant and Department of Haematology, The John Radcliffe Hospital, Oxford, UK

Derwood H. Pamphilon MD, MRCPCH, FRCP, FRCPath
Consultant Haematologist, NHS Blood & Transplant
Honorary Clinical Reader, Department of Cellular and Molecular Medicine, University of Bristol, Bristol, UK

Table of Contents

Recent evolution of transfusion medicine

Basic principles of immunohaematology

Essential immunology for transfusion medicine

Human blood group systems

Human leucocyte antigens

Platelet and neutrophil antigens

Complications of transfusion

Approach to the investigation and management of transfusion reactions

Haemolytic transfusion reactions

Febrile and allergic transfusion reactions

Transfusion-related acute lung injury

Transfusion-related immunomodulation

Micro-chimerism and transfusion-associated graft-versus-host disease

Post-tranfusion purpura

Tranfusion-transmitted infections

Bacterial contamination

Variant Creutzfeldt-Jakob disease

Emerging infections and transfusion safety

Practice in blood centres and hospitals

Regulatory aspects of blood transfusion

The role of haemovigilance in transfusion safety

Donors and blood collection

Blood donation testing and the safety of the blood supply

Production and storage of blood components

Medicolegal aspects of transfusion practice

Blood transfusion in hospitals

Blood transfusion in a global context

Clinical transfusion practice

Good blood management: the effective and safe use of blood components

Prenatal and childhood transfusions

Haematological disease

Blood transfusion in the management of patients with haemoglobinopathies

Massive blood loss

Inherited and acquired coagulation disorders

Recombinant proteins in diagnosis and therapy

Immunodeficiency and immunoglobulin therapy

Alternatives to transfusion

The principles of bloodless medicine and surgery

Autologous transfusion

Blood substitutes

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