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9780444509598

Progress in Medicinal Chemistry

by ;
  • ISBN13:

    9780444509598

  • ISBN10:

    0444509593

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2002-04-24
  • Publisher: Elsevier Science
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Supplemental Materials

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Summary

The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a??quality lead???, where these??quality leads??? come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.*Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect

Table of Contents

List of Contributors
vii
Preface v
Caspase Inhibitors as Anti-inflammatory and Antiapoptotic Agents
1(72)
Piotr P. Graczyk
RNA as a Drug Target
73(48)
Martin J. Drysdale
Georg Lentzen
Natalia Matassova
Alastair I.H. Murchie
Fareed Aboul-Ela
Mohammad Afshar
ACAT Inhibitors: The Search for a Novel and Effective Treatment of Hypercholesterolemia and Atherosclerosis
121(52)
Drago R. Sliskovic
Joseph A. Picard
Brian R. Krause
Growth Hormone Secretagogues: Discovery of Small Orally Active Molecules by Peptidomimetic Strategies
173(42)
Michael Ankersen
Inhibitors of Hepatitis C Virus NS3 4A Protease: An Overdue Line of Therapy
215(42)
Robert B. Perni
Ann D. Kwong
Subject Index 257(6)
Author Index (Vols. 1-39) 263(6)
Subject Index (Vols. 1-39) 269

Supplemental Materials

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The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

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