Psychopathology of Functional Somatic Syndromes : Neurobiology and Illness Behavior in Chronic Fatigue Syndrome, Fibromyalgia, Gulf War Illness, Irritable Bowel Syndrome, and Premenstrual Syndrome

by Manu, Peter

• ISBN13: 9780789012609
• ISBN10: 078901260X
• Format: Paperback
• Copyright: 2004-03-09
• Publisher: Routledge

Summary

Learn how a patient's behavior can factor into the prognosis of medically unexplainable illness! The Psychopathology of Functional Somatic Syndromes examines the link between mental illness and physical syndromes that lack organic disease explanations, including chronic fatigue syndrome, fibromyalgia, premenstrual dysphoria, irritable bowel, and Gulf War illness. The author has evaluated the best research work of the past 20 years to determine the association between psychopathology and functional illness, the biological gradient between somatic and psychological symptoms, and the manifestations of dysfunctional coping. The Psychopathology of Functional Somatic Syndromes challenges recent conceptualizations of functional somatic syndromes as brain disorders connected to affective spectrum disorder, serotonin deficiency, cerebral hypoperfusion or abnormal hypothalamic-pituitary-adrenal function and highlights the importance of abnormal illness behavior, sexual victimization, and maladaptive coping for the production and maintenance of these disorders. The Psychopathology of Functional Somatic Syndromes explores observations on the neurobiology and the personality abnormalities of patients made from structured data collected over a period of several years. It describes modern perceptions of functional somatic syndromes and how they have evolved into a tightly knit family of self-standing syndromes with a common core. The book examines the correlation between the burden of psychopathology and the physical features of these illnesses; reviews advances made in the appraisal of the neuroanatomy, neuropsychology, and neurochemistry of functional syndromes; and focuses on the connection between measurable dimensions of personality, coping, and illness behavior and the prognosis of medically unexplainable illnesses. The Psychopathology of Functional Somatic Syndromes examines: psychiatric morbidity brain perfusion post-traumatic stress in Gulf War illness the spectrum of mood disorders the hypothalamatic-pituitary-adrenal axis the sexual victimization of patients and much more! The Psychopathology of Functional Somatic Syndromes is an essential resource for psychiatrists and psychologists working in outpatient practice.

Author Biography

Peter Manu is Professor of Clinical Medicine and Professor of Clinical Psychiatry at Albert Einstein College of Medicine at Yeshiva University in New York, and teaches at Long Island Jewish Medical Center, where he is Director of Medical Services at the Zucker Hillside Hospital.

Table of Contents

Introduction	1	(8)
PART I: THE CLINICAL MANIFESTATIONS OF FUNCTIONAL SYNDROMES
Chapter 1. The Modern Conceptualization of Unexplained Symptoms	9	(14)
Chronic Fatigue Syndrome	9	(3)
Fibromyalgia	12	(4)
Premenstrual Syndrome	16	(1)
Irritable Bowel Syndrome	17	(2)
Gulf War Illness	19	(4)
Chapter 2. A Tight-Knit Family of Syndromes	23	(12)
PART II: PSYCHIATRIC MORBIDITY IN FUNCTIONAL SOMATIC ILLNESS
Chapter 3. Depression and Somatization in Chronic Fatigue Syndrome	35	(16)
Mood Disorders and Chronic Fatigue Syndrome	35	(7)
Somatization Disorder and Chronic Fatigue Syndrome	42	(6)
Psychopathology and Chronic Fatigue: Environmental or Genetic Covariation?	48	(3)
Chapter 4. Somatization and Depression in Fibromyalgia	51	(14)
Chapter 5. The Spectrum of Mood Disorders Associated with Premenstrual Dysphoria	65	(8)
Chapter 6. Anxiety, Depression, and Somatization in Irritable Bowel Syndrome	73	(10)
Chapter 7. Somatization and Posttraumatic Stress in Gulf War Illness	83	(14)
PART III: THE PSYCHOBIOLOGY OF FUNCTIONAL SOMATIC SYNDROMES
Chapter 8. Neuroanatomy and Brain Perfusion in Functional Somatic Syndromes	97	(20)
Magnetic Resonance and Single Photon Emission Imaging in Chronic Fatigue Syndrome	97	(12)
Cerebral Perfusion in Fibromyalgia	109	(3)
Magnetic Resonance Imaging and Premenstrual Brain Volume	112	(1)
Functional Magnetic Resonance in Irritable Bowel Syndrome	113	(2)
Magnetic Resonance and Single Photon Emission Tomography in Gulf War Syndrome	115	(1)
Conclusion	116	(1)
Chapter 9. Neuropsychological Deficits in Functional Somatic Illness	117	(14)
Chronic Fatigue Syndrome	117	(7)
Gulf War Illness	124	(7)
Chapter 10. The Hypothalamic-Pituitary-Adrenal Axis in Functional Somatic Illness	131	(22)
Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Chronic Fatigue Syndrome	131	(10)
The Reactivity of the Hypothalamic-Pituitary-Adrenal Axis in Fibromyalgia	141	(6)
Cortisol Levels in Irritable Bowel Syndrome	147	(2)
Assessment of the Hypothalamic-Pituitary-Adrenal Axis In Premenstrual Syndrome	149	(4)
Chapter 11. Serotonin Metabolism in Functional Somatic Illness	153	(18)
Serotonergic Neurotransmission in Chronic Fatigue Syndrome	153	(4)
Serotonin Metabolism in Fibromyalgia	157	(4)
Serotonergic Function in Premenstrual Syndrome	161	(10)
PART IV: ABNORMAL PERSONALITY AND ILLNESS BEHAVIOR IN FUNCTIONAL SOMATIC SYNDROMES
Chapter 12. Abnormal Personality In Functional Somatic Syndromes	171	(28)
Chronic Fatigue Syndrome	171	(13)
Fibromyalgia	184	(2)
Irritable Bowel Syndrome	186	(2)
Premenstrual Syndrome	188	(5)
Gulf War Illness	193	(4)
Conclusion	197	(2)
Chapter 13. The Sexual Victimization of Patients with Functional Somatic Syndromes	199	(14)
Fibromyalgia	199	(5)
Irritable Bowel Syndrome	204	(6)
Chronic Fatigue Syndrome	210	(3)
Chapter 14. Somatic Attributions in Functional Illness	213	(8)
Chronic Fatigue Syndrome	213	(5)
Fibromyalgia	218	(2)
Premenstrual Syndrome	220	(1)
Chapter 15. Maladaptive Coping in Functional Somatic Syndromes	221	(24)
Chronic Fatigue Syndrome	221	(9)
Fibromyalgia	230	(8)
Irritable Bowel Syndrome	238	(7)
References	245	(40)
Index	285