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Pulmonary Physiology

by
ISBN13:

9780071387651

ISBN10:
007138765X
Format:
Paperback
Pub. Date:
8/23/2002
Publisher(s):
MCGRAW-HILL PROFESSIONAL

Summary

Understanding pulmonary physiology begins with a solid emphasis on essential concepts. And that's exactly the base of knowledge that you'll get from Pulmonary Physiology. Through six successful editions, this well-illustrated, concise, yet complete text has immersed medical students and residents in all the critical topics of this demanding discipline-from the mechanics of breathing to the respiratory system under stress. Learning objectives are clearly mapped out for each chapter, which then promotes self-instruction of the material. And when it comes time to test your knowledge, clinical problems prompt you to apply what you've learned to realistic clinical scenarios.

Author Biography

Michael G. Levitzky is Professor of Physiology and Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana.

Table of Contents

Preface ix
Function & Structure of the Respiratory System
1(10)
Objectives
1(1)
Functions of the Respiratory System
2(2)
Structure of the Respiratory System
4(6)
Key Concepts
10(1)
Suggested Readings
10(1)
Mechanics of Breathing
11(43)
Objectives
11(1)
Generation of a Pressure Gradient Between Atmosphere & Alveoli
12(8)
Pressure-Volume Relationships in the Respiratory System
20(9)
Interaction of Lung & Chest Wall: The Static Pressure-Volume Curve
29(3)
Airways Resistance
32(17)
The Work of Breathing
49(1)
Key Concepts
50(1)
Clinical Problems
51(1)
Suggested Readings
52(2)
Alveolar Ventilation
54(32)
Objectives
54(1)
The Lung Volumes
54(3)
Measurement of the Lung Volumes
57(8)
Anatomic Dead Space & Alveolar Ventilation
65(2)
Measurement of Alveolar Ventilation
67(4)
Alveolar Ventilation & Alveolar Oxygen & Carbon Dioxide Levels
71(4)
Regional Distribution of Alveolar Ventilation
75(4)
The Closing Volume
79(2)
The Effects of Aging
81(1)
Key Concepts
82(1)
Clinical Problems
83(1)
Suggested Readings
84(2)
Blood Flow to the Lung
86(27)
Objectives
86(1)
The Bronchial Circulation
87(2)
The Functional Anatomy of the Pulmonary Circulation
89(3)
Pulmonary Vascular Resistance
92(7)
The Regional Distribution of pulmonary Blood Flow: The Zones of the Lung
99(6)
Hypoxic Pulmonary Vasoconstriction
105(2)
Pulmonary Edema
107(3)
Key Concepts
110(1)
Clinical Problems
111(1)
Suggested Readings
112(1)
Ventilation-Perfusion Relationships
113(17)
Objectives
113(1)
The Concept of Matching Ventilation & Perfusion
113(1)
Consequences of High & Low V/Q
114(2)
Testing for Nonuniform Distribution of Inspired Gas & Pulmonary Blood Flow
116(9)
Regional V/Q Differences & Their Consequences in the Lung
125(3)
Key Concepts
128(1)
Clinical Problems
128(1)
Suggested Readings
129(1)
Diffusion of Gases
130(12)
Objectives
130(1)
Fick's Law for Diffusion
130(3)
Limitations of Gas Transfer
133(2)
Diffusion of Oxygen
135(2)
Diffusion of Carbon Dioxide
137(1)
Measurement of Diffusing Capacity
137(3)
Key Concepts
140(1)
Clinical Problems
140(1)
Suggested Readings
141(1)
The Transport of Oxygen & Carbon Dioxide in the Blood
142(21)
Objectives
142(1)
Transport of Oxygen by the Blood
142(3)
Hemoglobin & the Physiologic Implications of the Oxyhemoglobin Dissociation Curve
145(3)
Influences on the Oxyhemoglobin Dissociation Curve
148(8)
Transport of Carbon Dioxide by the Blood
156(2)
The Carbon Dioxide Dissociation Curve
158(1)
The Bohr & Haldane Effects Explained
159(2)
Key Concepts
161(1)
Clinical Problems
161(1)
Suggested Readings
162(1)
The Regulation of Acid-Base Status
163(25)
Objectives
163(1)
The Chemistry of Acids, Bases, & Buffers
163(3)
Buffer Systems of the Human Body
166(5)
Acidosis & Alkalosis
171(4)
Respiratory & Renal Compensatory Mechanisms
175(3)
Clinical Interpretation of Blood Gases & Acid-Base Status
178(2)
The Causes of Hypoxia
180(3)
Key Concepts
183(1)
Clinical Problems
184(3)
Suggested Readings
187(1)
The Control of Breathing
188(27)
Objectives
188(2)
The Generation of Spontaneous Rhythmicity
190(1)
The Medullary Respiratory Center
191(2)
The Pontine Respiratory Group
193(1)
Spinal Pathways
194(1)
Reflex Mechanisms of Respiratory Control
194(6)
Influences of Higher Centers
200(1)
The Response to Carbon Dioxide
201(7)
The Response to Hydrogen Ions
208(1)
The Response to Hypoxia
209(1)
The Response to Exercise
210(2)
Key Concepts
212(1)
Clinical Problems
213(1)
Suggested Readings
214(1)
Nonrespiratory Functions of the Lung
215(13)
Objectives
215(1)
Pulmonary Defense Mechanisms
215(6)
Nonrespiratory Functions of the Pulmonary Circulation
221(2)
Metabolic Functions of the Lung
223(3)
Key Concepts
226(1)
Suggested Readings
226(2)
The Respiratory System Under Stress
228(20)
Objectives
228(1)
Exercise & the Respiratory System
228(6)
Altitude & Acclimatization
234(6)
Diving & the Respiratory System
240(6)
Key Concepts
246(1)
Clinical Problems
246(1)
Suggested Readings
247(1)
Clinical Problem Answers 248(13)
Appendix 261(4)
I. Symbols Used in Respiratory Physiology
261(1)
II. The Laws Governing the Behavior of Gases
261(1)
III. Frequently Used Equations
262(1)
IV. Pulmonary Function Test Decision Tree
263(1)
V. Table of Normal Respiratory and Circulatory Values
264(1)
VI. General Suggested Readings
264(1)
Index 265


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