Quantification of Brain Function Using Pet

by Myers, Ralph; Cunningham, Vin; Bailey, Dale L.; Jones, Terry

• ISBN13: 9780123897602
• ISBN10: 0123897602
• Format: Hardcover
• Copyright: 1996-07-01
• Publisher: Academic Pr

Summary

Functional imaging of the brain is one of the most rapidly advancing areas of neuroscience and Positron Emission Tomography (PET) plays a major role in this progress. This book provides a comprehensive overview of the current status of PET and state-of-the-art neuroimaging. It is comprised of summaries of the presentations by experts in the field. Topics covered include radiotracer selection, advances in instrumentation, image reconstruction and data analysis, and statistical mapping of brain activity. This book focuses on the accuracy of the functional image and the strategies for addressing clinical, scientific, and diagnostic questions. Covers the PET imaging process from tracer selection to analysis and interpretation Contains 79 concise reports with abundant illustrations The definitive state-of-the-art book for functional neuroscience with PET

Table of Contents

Tracer Selection

In Vivo-In Vitro Correlations: An Example from Vesicular Monoamine Transporters

The Noncatechol Tracer 6-flouro-m-tyrosine: Extrastriatal Distribution of Dopaminergic Function

Quantification of Dopamine Receptors and Transporter in Rat Striatum Using a Small Animal PET Scanner

Applicability of Experimental PET in Animal Models for the Interpretation of Incidental Findings in Human Stroke

The MOC Counter--A Pharmacological Tool for the in Vivo Measurement of Ligand Occupancy Indices in the Human Brain

Autoradiography As a Tool for PET/SPECT Tracer Selection and Assessment

Radioactive Metabolites of the 5-HT 1A Receptor Radioligand, [O-methyl - 11 C]WAY-100635, in Humans

11 C-Nefopam as a Potential PET Tracer of Serotonin Reuptake Sites: Initial Findings in Living Pig Brain

The Effect of Amine pKa on the Transport and Binding of Amphetamine Analogues in Pig Brain: An in Vivo Comparison of B, B-Difluoro[N-methyl 11 C ]methamphetamine Using PET

Tacer Selection Summary

Data Acquisition

Application of Simultaneous Emission and Transmission Scanningto Quantitative Cerebral PET

A New PET Camera for Noninvasive Quantitation of Physiological Functional Parametric Images: HEADTOME-V-DUAL

Development of an On-Line Blood Detector System for PET Studies in Small Animals

Noninvasive Determination of Arterial Input of 15 O Tracers Using a Dual Cutaneous B-Detector Set above the Radial Artery

Dispersion Correction for Automatic Sampling of O-15 Labeled H 2 O and Red Blood Cells

Scatter Correction for Brain Receptor Quantitation in 3D PET

Implementation of 3D Acquisition,Reconstruction and Analysis of Dynamic 18 F Fluorodopa Studies

Quantitation of the [ 18 F]Fluorodopa Uptake in the Human Striata in 3D PET with the ETM Scatter Correction

3D PET Activation Studies with H 2 15 O Bolus Injection: Count Rate Performance and Dose Optimization

Optimization of Noninvasive Activation Studies with O-15-Water and 3D PET

Data Acquisition Summary

Data Processing

Sinogram Recovery of Dynamic PET Using Principal Component Analysis and Projections onto Convex Sets

Minimum Cross Entropy Reconstruction of PET Images Using Prior Anatomical Information Obtained fro<$$$>

Table of Contents provided by Publisher. All Rights Reserved.