Rang & Dale's Pharmacology

by Rang, H. P.; Dale, M. M.; Ritter, J. M.; Flower, R. J.; Henderson, G.

• ISBN13: 9780702034718
• ISBN10: 0702034711
• Edition: 7th
• Format: Paperback
• Copyright: 2011-05-04
• Publisher: Elsevier Science Health Science

Summary

Rang & Dale's Pharmacology provides you with all the knowledge you need to get through your pharmacology course and beyond. Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson present a clear and accessible approach to the analysis of therapeutic agents at the cellular and molecular level through detailed diagrams, full-color illustrations, and pedagogical features. Plus, USMLE-style review questions and additional learning tools online at studentconsult.com make this the perfect resource to turn to for a full understanding of key concepts in pharmacology. Access the fully searchable text online at studentconsult.com, along with 500 USMLE-style multiple-choice review questions, downloadable images, and online only references. Find and cross-reference information quickly using a color-coded layout that makes navigation easy. Effectively understand and review key concepts through detailed diagrams and full-color illustrations that clarify even the most complex concepts. Reinforce your learning with key points boxes and clinical uses boxes that highlight crucial information and clinical applications. Apply current best practices and clinical applications through thoroughly updated and revised drug information. Stay current with the latest developments in the field thanks to major updates in chapters such as How Drugs Act; Amino Acid Transmitters; Analgesic Drugs; Antidepressant Drugs; and Drug Addiction, Dependence & Abuse. Tap into comprehensive content tailored to your courses with new and reorganized chapters on Host Defense; Inflammatory Mediators; Pharmacogenetics, Pharmacogenomics & Personalized Medicine; Hydroxytoptomine & The Pharmacy of Migraine; and Purines. Build your basic and clinical pharmacology knowledge with a comprehensive yet easy-to-use text

Table of Contents

General principles

What is pharmacology?

How drugs act: general principles

How drugs act: molecular aspects

How drugs act: cellular aspects-excitation, contraction and secretion

Cell proliferation, apoptosis, repair and regeneration

Cellular mechanisms: host defence

Method and measurement in pharmacology

Drug absorption and distribution

Drug metabolism and elimination

Pharmacokinetics

Pharmacogenetics, pharmacogenomics and 'personalised medicine'

Chemical mediators

Chemical mediators and the autonomic nervous system

Cholinergic transmission

Noradrenergic transmission

5-Hydroxytryptamine and the pharmacology of migraine

Purines

Local hormones: cytokines, biologically active lipids, amines and peptides

Cannabinoids

Peptides and proteins as mediators

Nitric oxide

Drugs affecting major organ systems

The heart

The vascular system

Atherosclerosis and lipoprotein metabolism

Haemostasis and thrombosis

Haemopoietic system and treatment of anaemia

Anti-inflammatory and immunosuppressant drugs

The respiratory system

The kidney

The gastrointestinal tract

The control of blood glucose and drug treatment of diabetes mellitus

Obesity

The pituitary and the adrenal cortex

The thyroid

The reproductive system

Bone metabolism

The nervous system

Chemical transmission and drug action in the central nervous system

Amino acid transmitters

Other transmitters and modulators

Neurodegenerative diseases

General anaesthetic agents

Analgesic drugs

Local anaesthetics and other drugs affecting sodium channels

Anxiolytic and hypnotic drugs

Antiepileptic drugs

Antipsychotic drugs

Antidepressant drugs

CNS stimulants and psychotomimetic drugs

Drug addiction, dependence and abuse

Drugs used for the treatment of infections, cancer and immunological disorders

Basic principles of antimicrobial chemotherapy

Antibacterial drugs

Antiviral drugs

Antifungal drugs

Antiprotozoal drugs

Anthelminthic drugs

Anticancer drugs

Special topics

Individual variation and drug interaction

Harmful effects of drugs

Lifestyle drugs and drugs in sport

Biopharmaceuticals and gene therapy

Drug discovery and development

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