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9780896037649

Transgenics in Endocrinology

by ; ;
  • ISBN13:

    9780896037649

  • ISBN10:

    0896037649

  • Format: Hardcover
  • Copyright: 2001-08-01
  • Publisher: Humana Pr Inc

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Summary

A panel of expert clinical and basic investigators summarize the state-of-the-art in the use of transgenic technology in a broad range of endocrinological applications. Up-to-date and comprehensive, Transgenics in Endocrinology reviews the most recent developments in the analysis of endocrine physiology and its pathologies through mouse models, and provides a host of creative approaches to understand better the complex processes that are characteristic of hormonal systems.

Table of Contents

Preface v
Contributors ix
Germline Genetic Engineering Techniques in Endocrinology
1(18)
Albert S. Y. Chang
Michael J. Reardon
Francesco J. DeMayo
The Transgenic Mouse in Studies of Mammalian Sexual Differentiation
19(22)
Deanne J. Whitworth
Richard R. Behringer
The In Vivo Function of Mullerian-Inhibiting Substance During Mammalian Sexual Development
41(20)
Yuji Mishina
Control of Ovarian Function
61(30)
Julia A. Elvin
Martin M. Matzuk
Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression
91(24)
Emiliana Borrelli
T. Rajendra Kumar
Paolo Sassone-Corsi
Functional Analysis of the Bc12 Gene Family in Transgenic Mice
115(32)
Andrea J. Ross
Grant R. macGregor
The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis
147(18)
Peter J. Donovan
Maria P. de Miguel
Gene Knockout Approaches to Steroidogenesis
165(8)
Tomonobu Hasegawa
Liping Zhao
Kathleen M. Caron
Morag Young
Keith L. Parker
The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo
173(32)
John P. Lydon
Selma Soyal
Bert W. O'Malley
Preeti M. Ismail
Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development
205(26)
Tiffany N. Seagroves
Jeffrey M. Rosen
Prolactin and the Prolactin Receptor
231(14)
Nelson D. Horseman
Transgenic Models for Oxytocin and Vasopressin
245(16)
Larry J. Young
Thomas R. Insel
Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function
261(36)
Ruth A. Keri
John H. Nilson
Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation
297(22)
Daniel J. Bernard
Teresa K. Woodruff
Transgenic Analysis of the Proopiomelanocortin Neuroendocrine Systems
319(20)
Malcolm J. Low
Marcelo Rubinstein
E. Cheng Chan
Overexpression and Targeted Disruption of Genes Involved in the Control of Growth, Food Intake, and Obesity
339(32)
Andrzej Bartke
Michael Michalkiewicz
Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors
371(14)
Carolyn A. Bondy
Domenico Accili
Use of Transgenic Animals in Skeleton Biology
385(16)
Thomas Gunther
Mary Jo Doherty
Gerard Karsenty
Transgenic Mouse Models of Prostate Cancer
401(26)
Robert J. Matusik
Naoya Masumori
Tania Thomas
Thomas Case
Manik Paul
Susan Kasper
Scott B. Shappell
Neural- and Endocrine-Cell-Specific Immortalization Using Transgenic Approaches
427(42)
T. Rajendra Kumar
Index 469

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