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9781588294913

Essentials Of Restenosis

by ; ;
  • ISBN13:

    9781588294913

  • ISBN10:

    1588294919

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2007-08-22
  • Publisher: Humana Pr Inc

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Summary

Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists.

Table of Contents

Prefacep. v
Contributorsp. ix
List of Color Platesp. xiii
Pathophysiology and Diagnosis
Unraveling the Complex Process of Restenosis From Bench to Bedsidep. 3
Epidemiology and Pathogenesis of Restenosisp. 7
Clinical Presentation of Restenosisp. 29
Pathological Anatomy of Restenosisp. 47
The Influence of Shear Stress on Restenosisp. 59
The Immune System in the Pathogenesis of Vascular Proliferative Diseasep. 85
Animal Restenosis Models: From the Ideal Model to the Ideal Studyp. 131
Genetic Basis of Restenosis
The Genomics of Restenosisp. 153
Gene-Expression Profiling and Restenosisp. 167
Proteomics and Restenosisp. 175
Contribution of Circulating Progenitor Cells to Vascular Repair and Lesion Formationp. 185
Cell Cycle Regulators and Vascular Proliferative Diseasesp. 199
Arterial Remodelingp. 213
The Role of eNOS in Vascular Diseasesp. 227
Diagnosis of Restenosis
The Use of Pressure Gradient in the Diagnosis of Restenosisp. 247
The Use of Radio Isotopes in the Diagnosis of Vascular Proliferative Diseasep. 257
Magnetic Resonance Imaging for Restenosisp. 277
Coronary Imaging With Multislice Spiral Computed Tomographyp. 287
Therapy of Restenosis
Pharmacotherapy of Restenosisp. 301
Brachytherapyp. 307
Preclinical Data of Eluting Stentsp. 333
Clinical Data of Eluting Stentsp. 353
Biodegradable Stentsp. 369
Biotechnology in the Treatment of Restenosis
Vascular Gene Therapyp. 379
Antisense and ODN Transcription Factors in the Treatment of Vascular Proliferative Diseasep. 395
Cell Cycle Approaches to the Treatment of In-Stent Restenosisp. 407
Local Gene and Cell Delivery Devicesp. 419
Indexp. 443
Table of Contents provided by Ingram. All Rights Reserved.

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