In Silico Protein Design

by Frenz, Christopher M.

• ISBN13: 9781907568268
• ISBN10: 1907568263
• Format: Hardcover
• Copyright: 2013-12-30
• Publisher: Biohealthcare Pub

Summary

This book covers the computational techniques that are most frequently utilized by protein engineers. The advent of biotechnology has made proteins play an increasingly important role as medicinal therapeutics, catalysts in the chemical process industries, and numerous other applications. Many of these applications are dependent on the field of protein engineering to either modify existing proteins to alter/enhance their functionality or to create novel proteins capable of novel functionality. In the last decade, the rapid advances made by the computer industry have allowed for the creation of computer systems capable of modelling proteins to become relatively commonplace. As such, there has been a marked increase in the use of computational methods to engineer proteins. The book is written in a way that assumes that the reader has neither a background in protein biochemistry or computational biology, so that any scientist is presented with all of the fundamentals he/she needs to understand in order to begin applying computational methods to the design of proteins.