Specious Science Why Experiments on Animals Harm Humans

by Greek, M. D., C. Ray; Greek, D.V.M., Jean Swingle

• ISBN13: 9780826415387
• ISBN10: 0826415385
• Format: Paperback
• Copyright: 2003-10-28
• Publisher: Bloomsbury Academic

Summary

This book provides the scientific underpinning for the Greeks' philosophy of "do no harm to any animal, human or not," by examining paediatrics, diseases of the brain, new surgical techniques, in vitro research, the human genome and proteome projects.

Table of Contents

ACKNOWLEDGMENTS	9	(2)
PREFACE	11	(4)
1 THE PHILOSOPHY OF SCIENCE	15	(28)
Science and Animal Models	24	(3)
Why Animal Experimentation Persists	27	(5)
Science versus Pseudoscience	32	(5)
Alternative Medicine and Animal Models	37	(6)
2 THE THEORETICAL BASIS FOR THE FAILURE OF THE ANIMAL MODEL AS A SCIENTIFIC PARADIGM	43	(18)
The Animal Model and Evolution	44	(5)
Regulatory Genes	49	(3)
Follow the Money	52	(4)
Logic and the Animal Model	56	(3)
Conclusion	59	(2)
3 GENES, TECHNOLOGY, AND INTERNAL MEDICINE	61	(36)
The Lesson of the Microcosm	62	(9)
Animal Model Relevance to Cancer and Diseases of the Blood	71	(1)
Blood Diseases	72	(4)
Cancer	76	(21)
4 DEVELOPMENT OF MEDICATIONS	97	(36)
Genes and Drugs	97	(3)
Where Drugs Come From	100	(6)
Drug Testing with the Animal Model	106	(13)
Why the Animal Model Fails	119	(6)
Alternatives to Animal-Modeled Testing	125	(3)
Why Animal-Modeled Testing and Drug Development Continues	128	(5)
5 SURGERY	133	(37)
Early Surgery	134	(1)
Innovation in Sterile Technique	135	(3)
Development of Anesthesiology	138	(8)
Rising Dissatisfaction with Animal-Modeled Surgery	146	(1)
Innovations in Technology-Tools of the Trade	147	(3)
Blood Transfusions and Blood Type	150	(3)
Radiology: to Operate or Not, and Where	153	(4)
Ophthamology and Orthopedics	157	(10)
Surgical Training	167	(3)
6 PEDIATRICS	170	(34)
From Conception to Birth	172	(7)
The Truth about Teratogenic Testing	179	(7)
Birth Defects and Childhood Illnesses	186	(5)
Inherited Diseases	191	(9)
Part of the Problem	200	(1)
The Future of Studying Childhood Disease	201	(3)
7 DISEASES OF THE BRAIN	204	(40)
How the Brain Works	206	(1)
Injuries	207	(3)
Multiple Sclerosis	210	(4)
Motor Neuron Diseases	214	(1)
Alzheimer's Disease and Dementia	214	(8)
Parkinson's Disease	222	(6)
Epilepsy	228	(6)
Psychiatric Medications	234	(10)
8 BEYOND THE ANIMAL MODEL	244	(17)
Autopsy Studies	245	(1)
Clinical Research	246	(1)
Epidemiology	247	(1)
In Vitro Research	247	(1)
The Human Genome and Proteome Projects	248	(3)
Contributions from Other Scientific Fields	251	(1)
The Vital Role of Technology	252	(5)
The Power of Prevention	257	(1)
Changing the System	258	(3)
POSTSCRIPT	261	(6)
REFERENCES	267	(18)
INDEX	285