Step-Up : A High-Yield Systems-Based Review for the USMLE Step 1 Exam

by Samir Mehta; Edmund Milder; Adam Mirarchi

• ISBN13: 9780781738934
• ISBN10: 0781738938
• Edition: Revised
• Format: Paperback
• Copyright: 2001-10-01
• Publisher: Lippincott Williams & Wilkins

Table of Contents

Preface	ix
Acknowledgment	xi
The Nervous System	1	(37)
Development	1	(1)
Congenital Malformations of the Nervous System	2	(1)
Major Receptors of the Nervous System	3	(3)
Meninges, Flow of Cerebrospinal Fluid (CSF), and Pathologic Trauma	6	(1)
Blood Supply to the Brain	6	(2)
Lesions of the Cerebral Cortex	8	(1)
Important Pathways of the Spinal Cord	8	(3)
Important Pathways of the Brain Stem and Cerebrum	11	(3)
Muscles of the Eye	14	(2)
Classic Lesions of the Spinal Cord	16	(1)
Hypothalamus	17	(1)
Thalamus	18	(1)
Cranial Nerves	18	(3)
Contents of the Cavernous Sinus	21	(1)
Sleep	22	(1)
Seizure Types	23	(1)
Degenerative Diseases	24	(1)
Demyelinating Disease	25	(1)
Diseases Causing Dementia	26	(1)
Acute Meningitis	27	(1)
Nervous System Tumors	28	(1)
Nervous System Therapeutics	29	(1)
Psychiatry and Behavioral Science	30	(7)
Ethics and the Role of the Physician	37	(1)
The Cardiovascular System	38	(26)
Development	38	(3)
Physiology and Pathology of Heart Function	41	(7)
Atherosclerosis	48	(2)
Hypertension	50	(1)
Ischemic Heart Disease	51	(3)
Congestive Heart Failure	54	(1)
Intrinsic Diseases of the Heart	54	(6)
Shock	60	(2)
Therapeutics	62	(2)
The Respiratory System	64	(18)
Development	64	(2)
Physics and Function of the Lung	66	(3)
Control of Breathing	69	(2)
Lung Defenses	71	(1)
Adult Respiratory Distress Syndrome and Neonatal Respiratory Distress Syndrome	72	(1)
Pneumothorax	72	(1)
Pulmonary Vascular Disease (PVD)	73	(1)
Chronic Obstructive Pulmonary Disease (COPD)	74	(1)
Interstitial Lung Disease (ILD)	74	(1)
Environmental Lung Diseases (Pneumoconiosis)	75	(1)
Respiratory Infections	75	(4)
Cystic Fibrosis (CF)	79	(1)
Lung Neoplasms	80	(1)
Therapeutics	80	(2)
The Gastrointestinal System	82	(25)
Innervation and Blood Supply of the Gastrointestinal Tract	82	(1)
Hormones of the Gastrointestinal System	83	(1)
Important Congenital Malformations of the Gastrointestinal System	84	(1)
The Oropharynx, Esophagus, and Stomach	84	(3)
The Small Intestine, Large Intestine, and Rectum	87	(3)
Location of Absorption of Vitamins, Minerals, and Nutrients	90	(1)
Common Clinical Disorders of the Small Intestine, Large Intestine, and Rectum	91	(4)
Malabsorption Syndromes of the Small Intestine	95	(1)
Neoplastic Polyps	96	(1)
The Hepatobiliary System	97	(7)
The Pancreas	104	(1)
Bugs of the Gastrointestinal Tract	105	(1)
Therapeutics	105	(2)
The Renal System	107	(23)
Development	107	(1)
Gross Description of the Kidney	108	(2)
Normal Kidney Function	110	(6)
Glomerular Diseases	116	(3)
Urinary Tract Infections (UTIs)	119	(2)
Major Causes of Acute Renal Failure	121	(4)
Kidney Stone Formation	125	(1)
Adult Polycystic Kidney Disease (APKD) versus Normal Kidney	126	(1)
Renal Cancers	126	(2)
Therapeutics	128	(2)
The Endocrine System	130	(22)
Development	130	(1)
Congenital Malformations	131	(1)
Hormones	131	(6)
Calcium Homeostasis	137	(3)
Blood Glucose Levels	140	(1)
Diabetes Mellitus	141	(2)
Pituitary Disorders	143	(1)
Diabetes Insipidus	144	(3)
Thyroid	147	(3)
Pathathyroid Pathology	150	(1)
Multiple Endocrine Neoplasia (MEN) Syndrome	151	(1)
The Reproductive System	152	(28)
Determination of Sex	152	(1)
Female Development	152	(1)
Male Development	153	(2)
Spermatogenesis versus Oogenesis	155	(1)
Important Anatomical Features of the Perineum	156	(1)
Congenital Malformations	157	(1)
Genetic Abnormalities	158	(2)
Menarche, Menstruation, and Menopause	160	(4)
Pregnancy and Its Associated Complications	164	(2)
Gynecologic Diagnostic Tests	166	(1)
Sexually Transmitted Diseases (STDs)	167	(1)
Female Gynecologic Neoplasms	167	(3)
Breast Pathology	170	(1)
The Prostate	171	(1)
Testicular Pathology	171	(2)
Human Immunodeficiency Virus (HIV)	173	(2)
Therapeutics	175	(1)
Special Section	176	(4)
Timeline of the Developmental Stages of Life	176	(1)
The Family Unit and Related Concepts	177	(1)
Sexuality	178	(1)
Rape	179	(1)
Suicide	179	(1)
The Musculoskeletal System	180	(23)
Development	180	(2)
Bone Function and Metabolism	182	(1)
Bone, Cartilage, and Joint Disease	183	(4)
Systemic Lupus Erythematosus (SLE)	187	(4)
Brachial Plexus	191	(2)
Muscle Function and Dysfunction	193	(5)
Collagen Synthesis	198	(1)
The Inguinal Canal	199	(1)
Skin Disorders	200	(1)
Therapeutics	201	(2)
The Hematopoetic and Lymphoreticular System	203	(21)
Hematopoiesis Timetable	203	(1)
The Cells	203	(3)
The Organs of the Lymphoreticular System	206	(2)
Red Blood Cell Physiology	208	(1)
Lymphocyte Differentiation	209	(1)
Immunoglobulins	209	(1)
Complement System	210	(2)
Hypersensitivity Reactions	212	(1)
Immunodeficiencies	213	(3)
Thrombosis and the Clotting Cascade	216	(2)
Lymphoma	218	(1)
Leukemia	219	(1)
Anemia	220	(2)
Myeloproliferative Disorders	222	(1)
Therapeutics	223	(1)
Basic Concepts	224	(23)
DNA, RNA, and Protein	224	(9)
Bacterial Morphology and Genetics	233	(2)
Viral Genetics	235	(2)
Concepts in Pharmacology	237	(5)
Enzyme Kinetics	242	(2)
Biostatistics and Epidemiology	244	(3)
Appendix I: Drug Index	247	(44)
Appendix II: Bug Index	291	(16)
Appendix III: At the Bedside	307	(62)
Glossary	369
Index	315