Streptococcal Infections Clinical Aspects, Microbiology, and Molecular Pathogenesis

by Stevens, Dennis L.; Kaplan, Edward L.

• ISBN13: 9780195099218
• ISBN10: 0195099214
• Edition: 1st
• Format: Hardcover
• Copyright: 2000-01-06
• Publisher: Oxford University Press

Summary

Streptococcal Infections: Clinical Aspects, Microbiology, and Molecular Pathogenesis offers an in-depth examination of the spectrum of hemolytic streptococcal infections and their complications. Additionally, the volume incorporates and discusses aspects of pneumococcal, entrococcal, and oral streptococcal disease. The recent resurgence of rheumatic fever, concomitant outbreaks of severe systemic group A streptococcal infections (often accompanied by toxic shock), an increasing incidence of multiple antibiotic resistance among streptococcal species, and an intensified effort to develop effective streptococcal vaccines have brought renewed attention to the continuing role of streptococci for causing significant medical and public health problems in both industrialized and developing countries. Addressing clinical and epidemiological aspects, and microbiological and other approaches of the research scientist, this volume is the first to comprehensively address these clinically important organisms in many years. The contributors are internationally recognized for their expertise, making this book invaluable for infectious disease physicians, (internists, pediatricians, and family physicians, microbiologists, epidemiologists, and basic scientists with an interest in streptococcal infections and their complications.

Table of Contents

History of Hemolytic Streptococci and Associated Diseases	1	(18)
Floyd W. Denny, Jr.
Group A Beta-Hemolytic Streptococci: Virulence Factors, Pathogenesis, and Spectrum of Clinical Infections	19	(18)
Dennis L. Stevens
Group A Streptococcal Genetics and Virulence	37	(20)
P. Patrick Cleary
Kristen H. Pritchard
W. Michael McShan
Joseph J. Ferretti
Exotoxins of Streptococcus pyogenes	57	(19)
Manuela Roggiani
Aris P. Assimacopoulos
Patrick M. Schlievert
Streptococcal Pharyngitis	76	(26)
Stanford T. Shulman
Robert R. Tanz
Michael A. Gerber
Rheumatic Fever Pathogenesis	102	(31)
Elia M. Ayoub
Malak Kotb
Madeleine W. Cunningham
Rheumatic Fever	133	(11)
Milton Markowitz
Edward L. Kaplan
Streptococcal Pyoderma	144	(8)
Bascom F. Anthony
Acute Poststreptococcal Glomerulonephritis	152	(11)
Stig E. Holm
Annika Nordstrand
Dennis L. Stevens
Mari Norgren
Life-Threatening Streptococcal Infections: Scarlet Fever, Necrotizing Fasciitis, Myositis, Bacteremia, and Streptococcal Toxic Shock Syndrome	163	(17)
Dennis L. Stevens
Molecular Pathogenesis of Group B Streptococcal Disease in Newborns	180	(42)
Victor Nizet
Patricia Ferrieri
Craig E. Rubens
Group B Streptococcal Infections	222	(16)
Carol J. Baker
Group C and G Streptococci	238	(17)
J. Milton Gaviria
Alan L. Bisno
Nonhemolytic Streptococci	255	(11)
Judy A. Daly
Laboratory Evaluation of Streptococci	266	(14)
Diana R. Martin
Enterococcal Infections	280	(22)
Larry J. Strausbaugh
Michael S. Gilmore
Streptococcus pneumoniae Infections	302	(31)
Barry M. Gray
Oral Streptococci in Health and Disease	333	(38)
Mark C. Herzberg
Protection Against Group A Streptococcal Infection	371	(19)
Vincent A. Fischetti
Multivalent Group A Streptococcal Vaccines	390	(12)
James B. Dale
Group B Streptococcal Vaccines	402	(17)
Michael R. Wessels
Dennis L. Kasper
Vaccine Strategies for Streptococcus pneumoniae	419	(16)
David E. Briles
Edwin Swiatlo
Kathryn Edwards
Index	435