Systematic Reviews in Health Research Meta-Analysis in Context

by Egger, Matthias; Higgins, Julian P. T.; Davey Smith, George

• ISBN13: 9781405160506
• ISBN10: 1405160500
• Edition: 3rd
• Format: Hardcover
• Copyright: 2022-07-18
• Publisher: BMJ Books

Summary

Systematic Reviews in Health Research

Explore the cutting-edge of systematic reviews in healthcare

In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including:

• Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis
• Thorough update of 15 chapters focusing on systematic reviews of interventions
• Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)

A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

Author Biography

Matthias Egger is Professor of Epidemiology at the Institute for Social and Preventive Medicine, University of Bern, Switzerland and the Centre for Infectious Diseases Epidemiology and Research, University of Cape Town, South Africa.

Julian P. T. Higgins is Professor of Evidence Synthesis at Population Health Sciences, Bristol Medical School, University of Bristol, UK.

George Davey Smith is Professor of Clinical Epidemiology and Director of the MRC Integrative Epidemiology Unit at the University of Bristol, UK.

Table of Contents

Preface 

 

Foreword: Doug Altman’s prescience in recognizing the need to reduce biases before tackling imprecision in Systematic Reviews           

Iain Chalmers

 

Reprint: Altman DG. Some reflections on the evolution of meta-analysis.

 

Contributors

 

Companion Website

 

Chapter No.       Title

Rationale

1             Rationale of systematic reviews in health care

Principles and procedures

2             Principles of systematic reviewing

3             Identifying randomized controlled trials

4             Assessing the risk of bias in randomized trials

5             Investigating and dealing with publication bias and other reporting biases

6             Managing people and data

7             Reporting and appraisal of systematic reviews

Meta-analysis

8             Effect measures

9             Combining results in meta-analysis

10           Exploring heterogeneity

11           Dealing with missing outcome data in meta-analysis

12           Individual participant data meta-analysis

13           Network meta-analysis

14           Dose-response meta-analysis

Specific study designs

15           Systematic reviews of non-randomized studies of interventions

16           Systematic reviews of diagnostic accuracy

17           Systematic reviews of prognostic factor studies

18           Systematic reviews of prediction models

19           Systematic reviews of epidemiological studies of aetiology

20           Meta-analysis in genetic association studies

Cochrane and guideline development

21           Cochrane: Trusted evidence. Informed decisions. Better health.

22           Using systematic reviews in guideline development: the GRADE approach

Outlook

23           Innovations in systematic review production

24           Future for systematic reviews and meta-analysis

Software

25           Meta-analysis in Stata

26           Meta-analysis in R

27           Comprehensive Meta-analysis software

 

 

Index