Testosterone

by Nieschlag, Eberhard; Behre, Hermann M.; Nieschlag, Susan

• ISBN13: 9781107012905
• ISBN10: 1107012902
• Edition: 4th
• Format: Hardcover
• Copyright: 2012-09-17
• Publisher: Cambridge Univ Pr

Summary

Now in its fourth edition Testosterone: Action, Deficiency, Substitution provides the most up-to-date and comprehensive source of information on testosterone and its role in human physiology and pathology. It covers biosynthesis and mechanisms of action and reviews their effects on brain and behavior, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and the prostate. The therapeutic uses of testosterone preparations are carefully evaluated as well as its abuse and detection in competitive sport. This new edition also devotes sections to exploring the effects of testosterone on female physiology and sexual function, and the experimental use of testosterone in male hormonal contraception. Testosterone: Action, Deficiency, Substitution has been written and edited by world experts in the fields of clinical andrology and endocrinology and provides a unique and invaluable guide for andrologists, endocrinologists, urologists, internists and those working in reproductive medicine.

Table of Contents

Preface

The medical and cultural history of testosterone and the testes

Testosterone: biosynthesis, transport, metabolism and (non-genomic) actions

Pathophysiology of the androgen receptor

Methodology for measuring testosterone, DHT and SHBG in a clinical setting

The behavioral correlates of testosterone

The role of testosterone in spermatogenesis

Androgens and hair: a biological paradox with clinical consequences Valerie

Testosterone and bone

Androgens effects on the skeletal muscle

Testosterone and cardiovascular disease

Testosterone, obesity, diabetes and the metabolic syndrome

Testosterone and erection

Testosterone and the prostate

Clinical use of testosterone in hypogonadism and other conditions

Testosterone preparations for clinical use in males

Androgens in male senescence

Androgen therapy in non-gonadal disease

Review of guidelines on diagnosis and treatment of testosterone deficiency

Pathophysiology of estrogen action in men

Dehydroepiandrosterone (DHEA) and androstenedione

The state-of-the-art in the development of selective androgen receptor modulators (SARMs)

The essential role of testosterone in hormonal male contraception

Testosterone use in women

Detection of illegal use of androgens

Clinical effects of doping with anabolic steroids

Index

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