Thomas' Hematopoietic Cell Transplantation, 3rd Edition

by Editor: Karl G. Blume (Stanford University, California); Editor: Stephen J. Forman (City of Hope National Medical Center, Duarte, California); Editor: Frederick R. Appelbaum (Fred Hutchinson Cancer Research Center, Washington State)

• ISBN13: 9781405140119
• ISBN10: 1405140119
• Edition: 3rd
• Format: eBook
• Copyright: 2008-06-01
• Publisher: Wiley-Blackwell

Summary

NEW - the leading book in its field now fully updated and revised!Click here to access two FREE sample chapters!An Essential resource for all hematologists, oncologists, pathologists, pediatricians, immunologists and all others interested in this dynamic area of medicine!Why you should buy this book.... Extensive coverage of subject area - from the scientific basis to the view of the future Includes all experimental research and clinical application Combined the knowledge and expertise of over 170 international specialists Clear structure and layout Over 500 illustrations, including a colour plate sectionWhy buy the NEW edition...... New and fully revised to reflect the latest developments in this fast moving field 10 new chapters, covering some of the latest developments - see below for the complete tables of content

Table of Contents

Scientific Basis for Hematopoietic Cell Transplantation
A History of Bone Marrow Transplantation	p. 3
Uses and Growth of Hematopoietic Cell Transplantation	p. 9
Overview of Hematopoietic Cell Transplantation Immunology	p. 16
Histocompatibility	p. 31
Functional Evolution of the Major Histocompatibility Complex	p. 43
The Hematopoietic Microenvironment	p. 53
Molecular Aspects of Stem Cell Renewal	p. 62
Biology of Hematopoietic Stem and Progenitor Cells	p. Koichi Akash
Expansion of Hematopoietic Stem Cells	p. 96
Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells	p. 107
Clinical Trials of Gene Marking and Gene Therapy Using Hematopoietic Stem Cells	p. 118
Pharmacological Basis for High-Dose Chemotherapy	p. 130
Preparative Regimens and Modification of Regimen-Related Toxicities	p. 158
Radiotherapeutic Principles of Hematopoietic Cell Transplantation	p. 178
Radioimmunotherapy and Hematopoietic Cell Transplantation	p. 198
Pharmacology and the Use of Immunosuppressive Agents after Hematopoietic Cell Transplantation	p. 209
T-Cell Depletion to Prevent Graft-vs.-Host Disease	p. 221
Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation	p. 234
Antibody Mediated Purging	p. 244
Pharmacologic Purging of Bone Marrow	p. 254
Molecular Inhibition of Gene Expression in Hematopoietic Cells	p. 258
The Detection and Significance of Minimal Residual Disease	p. 272
Pathology of Hematopoietic Cell Transplantation	p. 286
Mechanisms of Tolerance	p. 300
The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases	p. 324
Murine Models for Graft-vs.-Host Disease	p. 344
The Pathophysiology of Graft-vs.-Host Disease	p. 353
Graft-versus-Tumor Responses	p. 369
Adoptive Immunotherapy with Antigen-Specific T Cells	p. 380
Autologous Graft-vs.-Host Disease	p. 405
Biostatistical Methods in Hematopoietic Cell Transplantation	p. 414
Outcomes Research in Hematopoietic Cell Transplantation	p. 434
Patient-Related Issues in Hematopoietic Cell Transplantation
The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation	p. 449
Clinical and Administrative Support for Hematopoietic Cell Transplant Programs	p. 463
Nursing Issues in Hematopoietic Cell Transplantation	p. 469
The PatientÆs Perspective	p. 483
Ethical Issues in Hematopoietic Cell Transplantation	p. 488
Psychosocial Issues in Hematopoietic Cell Transplantation	p. 497
Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients	p. 507
Sexuality after Hematopoietic Cell Transplantation	p. 519
Sources of Hematopoietic Cells for Human Transplant
Hematopoietic Cell Procurement, Processing and Transplantation: Regulation and Accreditation	p. 531
Hematopoietic Cell Donors	p. 538
Cord Blood Hematopoietic Cell Transplantation	p. 550
In Utero Transplantation	p. 565
Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy	p. 576
Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation	p. 588
Cryopreservation of Hematopoietic Cells	p. 599
Recombinant Growth Factors after Hematopoietic Cell Transplantation	p. 613
Hematopoietic Cell Donor Registries	p. 624
Complications and Their Management
Graft-vs.-Host Disease	p. 635
Bacterial Infections	p. 665
Fungal Infections after Hematopoietic Cell Transplantation	p. 683
Cytomegalovirus Infection	p. 701
Herpes Simplex Virus Infections	p. 727
Varicella-Zoster Virus Infections	p. 732
Epstein-Barr Virus Infection	p. 749
Other Viral Infections after Hematopoietic Cell Transplantation	p. 757
Gastrointestinal and Hepatic Complications	p. 769
Neurological Complications of Hematopoietic Cell Transplantation	p. 811
Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation	p. 824
Principles of Transfusion Support before and after Hematopoietic Cell Transplantation	p. 833
Immunological Reconstitution following Hematopoietic Cell Transplantation	p. 853
Vaccination of Hematopoietic Cell Transplant Recipients	p. 862
Pulmonary Complications after Hematopoietic Cell Transplantation	p. 873
Nutritional Support of Hematopoietic Cell Recipients	p. 883
Pain Management	p. 894
Oral Complications	p. 911
Growth and Development after Hematopoietic Cell Transplantation	p. 929
Delayed Complications after Hematopoietic Cell Transplantation	p. 944
Secondary Malignancies after Hematopoietic Cell Transplantation	p. 962
Allogeneic Transplantation for Acquired Diseases
Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia
Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria	p. 1002
Allogeneic Transplantation for Chronic Myeloid Leukemia	p. 1007
Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia	p. 1018
Allogeneic Hematopoietic Cell Transplantation for Adult Patients with Acute Myeloid Leukemia	p. 1025
Allogeneic Transplantation for Acute Myeloid Leukemia in Children	p. 1040
Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults	p. 1055
Allogeneic Transplantation for Acute Lymphoblastic Leukemia in ChildrenStella M. DaviesDavies, Stella M.	p. 1067
Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders	p. 1084
Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma	p. 1096
Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia	p. 1105
Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors	p. 1116
Hematopoietic Cell Transplantation from Unrelated Donors	p. 1132
Management of Relapse after Allogeneic Transplantation	p. 1150
Nonmyeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders	p. 1164
Allogeneic Hematopoietic Cell Transplantation for Solid Tumors	p. 1177
Autologous Transplantation for Acquired Diseases
Autologous and Allogeneic Hematopoietic Cell Transplantation for HodgkinÆs Disease	p. 1191
Autologous Hematopoietic Cell Transplantation for Non-HodgkinÆs Lymphoma	p. 1207
Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia	p. 1221
Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia	p. 1238
Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia	p. 1250
Autologous Hematopoietic Cell Transplantation for Multiple Myeloma	p. 1262
Autologous Hematopoietic Cell Transplantation for AL Amyloidosis	p. 1283
Hematopoietic Cell Transplantation for Breast Cancer	p. 1298
Hematopoietic Cell Transplantation in Germ Cell Tumors	p. 1308
Hematopoietic Cell Transplantation in Ovarian Carcinoma	p. 1320
Hematopoietic Cell Transplantation for Neuroblastoma	p. 1333
Hematopoietic Cell Transplantation for Brain Tumors	p. 1345
Hematopoietic Cell Transplantation for Pediatric Patients with Solid Tumors	p. 1354
AIDS and Hematopoietic Transplantation: HIV Infection	p. AIDS
Hematopoietic Stem Cell Transplantation for Autoimmune Diseases	p. 1385
Prevention and Therapy of Relapse following Autologous Hematopoietic Cell Transplantation	p. 1394
Allogeneic Transplantation for Inherited Disease
Marrow Transplantation in Thalassemia	p. 1409
Hematopoietic Cell Transplantation for Sickle Cell Disease	p. 1417
Hematopoietic Cell Transplantation for Immunodeficiency Diseases	p. 1430
Hematopoietic Cell Transplantation for Osteopetrosis	p. 1443
Hematopoietic Cell Transplantation for Storage Diseases	p. 1455
Hematopoietic Cell Transplantation for Macrophage and Granulocyte Disorders	p. 1471
Hematopoietic Cell Transplantation for Fanconi Anemia	p. 1483
The Future
Hematopoietic Cell Transplantation in the 21st Century	p. 1507
Colorplates, facing page 296
Index	p. 1511
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