Tuberculosis and the Tubercle Bacillus

by Cole, Stewart T.; Eisenach, Kathleen Davis; McMurray, David N.; Jacobs, Willam R., Jr.

• ISBN13: 9781555812959
• ISBN10: 1555812953
• Format: Hardcover
• Copyright: 2004-10-15
• Publisher: Amer Society for Microbiology

Summary

Second author, Kathleen Davis Eisenach, is with Univ. of Arkansas for the Medical Sciences, Little Rock. Provides clinical and epidemiological features of the disease-causing strains of tuberculosis, exploring genetics and cell structure. Examines various animal models and their roles in vaccine development and testing. DNLM: Tuberculosis--microbiology.

Table of Contents

Contributors	vii
Preface	xi
Introduction
Historical Perspectives
Global Burden of Tuberculosis: Past, Present, and Future	3	(12)
Liz Corbett
Mario Raviglione
Clinical and Epidemiological Perspectives
Overview of Clinical Tuberculosis	15	(18)
Philip C. Hopewell
Robert M. Jasmer
Molecular Epidemiology of Mycobacterium tuberculosis	33	(16)
M. Donald Cave
Megan Murray
Edward Nardell
Diagnostics
Clinical Mycobacteriology (Tuberculosis) Laboratory: Services and Methods	49	(22)
Leonid Heifets
Edward Desmond
Immune-Based Methods	71	(14)
Suman Laal
Yasir A. W. Skeiky
Molecular Diagnosis of Mycobacterial Infections	85	(16)
Betty A. Forbes
Gaby Pfyffer
Kathleen D. Eisenach
Current Therapies and Drug Resistance
Global Impact of Multidrug Resistance	101	(14)
Marcos A. Espinal
Max Salfinger
Mechanisms of Drug Resistance in Mycobacterium tuberculosis	115	(28)
Ying Zhang
Catherine Vilcheze
William R. Jacobs, Jr.
THE ORGANISM MYCOBACTERIUM TUBERCULOSIS
Genomics
Introduction to Functional Genomics of the Mycobacterium tuberculosis Complex	143	(12)
Priscille Brodin
Caroline Demangel
Stewart T. Cole
Comparative Genomics and Evolution of Mycobacterium bovis BCG	155	(10)
Roland Brosch
Marcel A. Behr
TB or Not TB: a Structural Genomics Mission?	165	(18)
Celia W. Goulding
Debnath Pal
David Eisenberg
Genetics
Gene Replacement Systems	183	(8)
Neil G. Stoker
P. Sander
J. M. Reyrat
Repetitive DNA in the Mycobacterium tuberculosis Complex	191	(12)
Stephen V. Gordon
Philip Supply
Mycobacteriophages and Tuberculosis	203	(16)
Graham F. Hatfull
Control of Mycobacterial Transcription	219	(16)
Issar Smith
William R. Bishai
Valakunja Nagaraja
Cell Structure
The Proteome of Mycobacterium tuberculosis	235	(26)
John T. Belisle
Miriam Braunstein
Ida Rosenkrands
Peter Andersen
The Cell Envelope of Mycobacterium tuberculosis with Special Reference to the Capsule and Outer Permeability Barrier	261	(14)
Philip Draper
Mamadou Daffe
Structure, Biosynthesis, and Genetics of the Mycolic Acid-Arabinogalactan-Peptidoglycan Complex	275	(12)
Sebabrata Mabapatra
Joyoti Basu
Patrick J. Brennan
Dean C. Crick
A Waxy Tale, by Mycobacterium tuberculosis	287	(22)
Laurent Kremer
Gurdyal S. Besra
Metabolism
General Metabolism and Biochemical Pathways of Tubercle Bacilli	309	(32)
Paul R. Wheeler
John S. Blanchard
Iron Metabolism in the Tubercle Bacillus and Other Mycobacteria	341	(18)
Luis E. N. Quadri
Colin Ratledge
Two-Component Systems, Protein Kinases, and Signal Transduction in Mycobacterium tuberculosis	359	(10)
Yossef Av-Gay
Vojo Deretic
Nucleic Acid Metabolism	369	(10)
Valerie Mizrahi
Michael Buckstein
Harvey Rubin
Transport Processes	379	(26)
Jean Content
Martine Braibant
Nancy D. Connell
Jose A. Ainsa
HOST-PATHOGEN INTERACTIONS
Phagocytic Uptake and Intracellular Survival
Receptor-Mediated Recognition of Mycobacterium tuberculosis by Host Cells	405	(22)
Matthew J. Fenton
Lee W. Riley
Larry S. Schlesinger
Mycobacterium tuberculosis: the Indigestible Microbe	427	(10)
David G. Russell
Intracellular Models of Mycobacterium tuberculosis Infection	437	(14)
John Chan
Richard F. Silver
Beate Kampmann
Robert S. Wallis
Dendritic Cells in Host Immunity to Mycobacterium tuberculosis	451	(14)
Marc Mendelson
Willem Hanekom
Gilla Kaplan
Host Immune Responses and Antigenic Variation
CD8 T Cells in Tuberculosis	465	(10)
Stefan H. E. Kaufmann
JoAnn L. Flynn
CD1 and Tuberculosis	475	(14)
Christopher C. Dascher
Michael B. Brenner
Th1 and Th2 Cytokines in the Human Immune Response to Tuberculosis	489	(8)
Peter F. Barnes
Ramakrishna Vankayalapati
Role of Antibody-Mediated Immunity in Host Defense against Mycobacterium tuberculosis	497	(16)
Aharona Glatman-Freedman
Arturo Casadevall
The PE and PPE Multigene Families of Mycobacteria	513	(16)
Michael J. Brennan
Nico C. Gey van Pittius
Clara Espitia
Animal Models
Mycobacterium marinarum and Fish and Frog Models of Infection	529	(8)
Michele Trucksis
Christopher L. Pritchett
Renate Reimschuessel
Experimental Infection Models of Tuberculosis in Domestic and Wild Animals	537	(10)
Bryce M. Buddle
John M. Pollock
R. Glyn Hewinson
Animal Models of Tuberculosis	547	(14)
JoAnne L. Flynn
Andrea M. Cooper
William Bishai
Tuberculosis Vaccine Preclinical Screening and Development	561	(12)
Ian M. Orme
Angelo A. Izzo
Index	573