Wintrobe's Clinical Hematology

by Greer, John P.; Foerster, John; Rodgers, George M.; Paraskevas, Frixos; Glader, Bertil; Arber, Daniel A.; Means, Robert T.

• ISBN13: 9780781765077
• ISBN10: 0781765072
• Edition: 12th
• Format: Hardcover
• Copyright: 2008-12-17
• Publisher: LWW

Summary

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology continues to be an industry leader with its ability to correlate basic science with the clinical practice of hematology. With the first edition of Wintrobe's Clinical Hematology published in 1942 clearly establishing hematology as a distinct subspecialty of Internal Medicine, the latest edition continues the influence of the Wintrobe name and helps to set this book apart from the competition. With its strong focus on the clinical aspects of hematology, the book has generated a strong following among internists and general practitioners who want a single resource to consult for their patients who present any blood related disorder. The Twelfth Edition is in full color for the first time, boasts a new editorial team, and includes expanded coverage of new medications and four new chapters on Newborn Anemias, Pathology of LHC, Spleen Tumors, and Myeloproliferative Disorders and Mast Cell Disease. A companion Website will offer the fully searchable text and an image bank.

Table of Contents

VOLUME 1 PART I Laboratory Hematology CH 1. Examination of the Blood and Bone Marrow CH 2. Clinical Flow Cytometry CH 3. Cytogenetics CH 4. Molecular Biology and Hematology PART II The Normal Hematologic System Section 1. Hematopoiesis CH 5. Origin and Development of Blood Cells Section 2. The Erythrocyte CH 6. Erythropoiesis CH 7. The Mature Erythrocyte CH 8. Destruction of Erythrocytes Section 3. Granulocytes and Monocytes CH 9. Neutrophilic Leukocytes CH 10. The Human Eosinophil CH 11. Basophilic Leukocytes: Mast Cells and Basophils CH 12. Mononuclear Phagocytes CH 13. Phagocytosis Section 4. The Lymphocytes CH 14. Lymphocytes and Lymphatic Organs CH 15. B Lymphocytes CH 16. T Lymphocytes and Natural Killer Cells CH 17. Effector Mechanisms in Immunity Section 5. Hemostasis CH 18. Megakaryocytes CH 19. Platelet Structure and Function in Hemostasis and Thrombosis CH 20. Blood Coagulation and Fibrinolysis CH 21. Endothelium: Angiogenesis and the Regulation of Hemostasis PART III Therapeutic Modalities CH 22. Red Cell, Platelet, and White Cell Antigens CH 23. Transfusion Medicine CH 24. Hematopoietic Stem Cell Transplantation CH 25. Gene Therapy for Hematologic Disorders PART IV Disorders of Red Cells Section 1. Introduction CH 26. Anemia: General Considerations Section 2. Disorders of Iron Metabolism and Heme Synthesis CH 27. Iron Deficiency and Related Disorders CH 28. Sideroblastic Anemias CH 29. Hemochromatosis CH 30. Porphyria Section 3. Hemolytic Anemia CH 31. Hereditary Spherocytosis, Hereditary Elliptocytosis, and Other Disorders Associated with Abnormalities of the Erythrocyte Membrane CH 32. Hereditary Hemolytic Anemias Due to Red Blood Cell Enzyme Disorders CH 33. Autoimmune Hemolytic Anemia CH 34. Alloimmune Hemolytic Disease of the Fetus and Newborn CH 35. Paroxysmal Nocturnal Hemoglobinuria CH 36. Acquired Nonimmune Hemolytic Disorders Section 4. Hereditary Disorders of Hemoglobin Structure and Synthesis CH 37. Sickle Cell Anemia and Other Sickling Syndromes CH 38. Thalassemias and Related Disorders: Quantitative Disorders of Hemoglobin Synthesis CH 39. Hemoglobins with Altered Oxygen Affinity, Unstable Hemoglobins, M-Hemoglobins, and Dyshemoglobinemias Section 5. Other Red Cells Disorders CH 40. Megaloblastic Anemias: Disorders of Impaired DNA Synthesis CH 41. Inherited Aplastic Anemia Syndromes CH 42. Acquired Aplastic Anemia CH 43. Red Cell Aplasia CH 44. Congenital Dyserythropoietic Anemias CH 45. Anemias Secondary to Chronic Disease and Systemic Disorders CH 46. Anemias During Pregnancy and the Postpartum Period CH 47. Anemias Unique to the Newborn Period CH 48. Erythrocytosis V O L U M E 2 PART V Disorders of Hemostasis and Coagulation Section 1. Introduction Section 2. Thrombocytopenia Section 3. Other Disorders of Primary Hemostasis Section 4. Coagulation Disorders Platelet Destruction Section 5 Thrombosis PART VI Nonmalignant Disorders of Leukocytes,the Spleen, and/or Immunoglobins PART VII Hematologic Malignancies Section 1. General Aspects Section 2. The Acute Leukemias Section 4. Lymphoproliferative Disorders Section 5. Plasma Cell Dyscrasias Appendices INDEX