The Biochemical Basis of Neuropharmacology

by Cooper, Jack R.; Bloom, Floyd E.; Roth, Robert H.

• ISBN13: 9780195140071
• ISBN10: 0195140079
• Edition: 8th
• Format: Hardcover
• Copyright: 2002-10-17
• Publisher: Oxford University Press

Summary

This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology, residents in psychiatry and neurology, and clinicians and scientists. Both authoritative and very readable, it has been thoroughly updated for each edition. In the Eighth Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics, the major problem of drug delivery to the brain, and the growing recognition of nicotinic receptors in the brain and their possible involvement in Alzheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of the illustrations.

Author Biography

Jack R. Cooper, Ph.D., is Emeritus Professor of Pharmacology, Yale University School of Medicine Floyd E. Bloom, M.D., is Chairman, Department of Neuropharmacology, The Scripps Research Institute Robert H. Roth, Ph.D., is Professor of Pharmacology and Psychiatry, Yale University School of Medicine

Table of Contents

Introduction	1	(6)
Cellular Foundations of Neuropharmacology	7	(32)
Molecular Foundations of Neuropharmacology	39	(26)
Receptors	65	(20)
Modulation of Synaptic Transmission	85	(20)
Amino Acid Transmitters	105	(46)
Acetylcholine	151	(30)
Norepinephrine and Epinephrine	181	(44)
Dopamine	225	(46)
Serotonin (5-Hydroxytryptamine), Histamine, and Adenosine	271	(50)
Neuroactive Peptides	321	(36)
Cellular Mechanisms in Learning and Memory	357	(16)
Treating Neurological and Psychiatric Diseases	373	(28)
Index	401