9780205318315

Drugs and Human Behavior

by
  • ISBN13:

    9780205318315

  • ISBN10:

    0205318312

  • Edition: 4th
  • Format: Paperback
  • Copyright: 1/1/2002
  • Publisher: Allyn & Bacon
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Summary

A valuable resource for any student majoring in the health sciences, Dr. Grilly's text examines human drug use from historical, societal, and biological perspectives. This scholarly overview provides a rich foundation for understanding drugs and their usage. In addition to describing basic pharmacological principles, Grilly discusses the general factors behind and approaches for dealing with drug tolerance, dependence, and abuse. By using the most up-to-date research, and by presenting data in concise, jargon-free prose, the author has created one of the most comprehensive and accessible books on the subject. Information is organized from the general to the specific, beginning with a historical perspective and subsequently moving through drug classifications, approaches to drug tolerance, dependence and abuse, psychological and behavioral effects, pharmacokinetics, mechanisms of action, common side effects, and current issues regarding drugs and their uses.

Table of Contents

Preface ix
Psychopharmacology in Perspective
1(19)
A Historical Overview of Psychopharmacology
2(1)
Predecessors to Modern Pharmacotherapies
3(3)
The Psychopharmacological Revolution
6(2)
Recreational and Social Drug Use
8(9)
Websites for Further Information
17(1)
Bibliography
18(2)
Basic Principles of Pharmacology
20(16)
Drugs and Receptors
22(3)
Dose--Response Relationships
25(6)
Drug Interactions
31(3)
Websites for Further Information
34(1)
Bibliography
35(1)
Pharmacokinetics
36(18)
Drug Absorption
36(2)
Routes of Administration
38(4)
Drug Distribution
42(3)
Metabolism
45(4)
Drug Excretion
49(1)
Implications of Pharmacokinetics in the Fetus and Neonate
50(2)
Websites for Further Information
52(1)
Bibliography
52(2)
Conduction and Neurotransmission
54(24)
The Neuron
55(1)
Conduction
56(6)
Neurotransmission
62(6)
Autoreceptors and Presynaptic Receptors
68(6)
Nonsynaptic Diffusion Neurotransmission
74(1)
Websites for Further Information
75(1)
Bibliography
76(2)
Neuroactive Ligands and the Nervous System
78(24)
Neurotransmitters, Neuromodulators, and Neurohormones
78(2)
Specific Neurotransmitters
80(8)
Neurotransmitters and Diet
88(2)
Structures and Subsystems of the Nervous System
90(7)
Drugs, the Nervous System, and Behavior: A Perspective
97(2)
Websites for Further Information
99(1)
Bibliography
99(3)
Tolerance and Dependence
102(32)
What Is Tolerance?
102(1)
Tolerance Mechanisms
103(11)
What Is Dependence?
114(11)
General Factors in Treatment for Drug Dependency
125(3)
State-Dependent Learning
128(1)
Websites for Further Information
129(1)
Bibliography
130(4)
Psychotropic Drug Classification
134(12)
Molecular Structure--Activity Relationships
134(2)
Depressant versus Stimulant Classifications
136(2)
Drug Use Classification
138(5)
Schedule-Controlled Drugs
143(2)
Websites for Further Information
145(1)
Bibliography
145(1)
Sedative--Hypnotics and Anxiolytics
146(47)
Alcohol (Ethanol)
147(23)
Barbiturates and Other Sedative--Hypnotics
170(2)
Inhalants: Anesthetic Gases and Solvents
172(1)
Anxiolytics
172(6)
Buspirone
178(1)
Antidepressants as Anxiolytics
179(2)
Kava---An Herbal Anxiolytic?
181(1)
Sedative--Hypnotics and Insomnia
181(2)
Websites for Further Information
183(1)
Bibliography
184(9)
Psychostimulants
193(45)
Caffeine
194(3)
Amphetamines and Related Drugs
197(8)
Cocaine
205(10)
Methcathinone
215(1)
Treatment of Cocaine and Amphetamine Abuse
216(3)
Nicotine
219(5)
Convulsants
224(1)
Antidepressants
225(1)
Pemoline
225(1)
Modafinil
225(1)
Psychostimulants, Learning, and Memory
226(3)
Website for Further Information
229(1)
Bibliography
229(9)
Opioids (Narcotics) and Their Antagonists
238(25)
Endogenous Opioid Peptides and Their Receptors
239(1)
Typical Opiates
240(1)
Behavioral and Physiological Effects of Opiates
241(3)
Opioid Pharmacodynamics
244(1)
Tolerance and Dependence on Opiates
245(3)
Treatment for Opiate Dependence
248(5)
The ``Overdose'' Phenomenon
253(2)
Legal Factors in the Narcotics Problem
255(2)
Opiate Antagonists: Potential Uses
257(2)
Websites for Further Information
259(1)
Bibliography
259(4)
Psychotomimetics, Psychedelics, and Hallucinogens
263(42)
Some General Characteristics of P/P/Hs
264(2)
Monoamine-Related P/P/Hs
266(10)
Cannabinoids
276(13)
Dissociative Anesthetics: Phencyclidine and Ketamine
289(5)
Anticholinergics
294(2)
Ibogaine
296(1)
P/P/Hs: The Human Experience
297(1)
Websites for Further Information
298(1)
Bibliography
299(6)
Antipsychotics
305(28)
Biochemical Hypotheses of Schizophrenia
306(8)
Present-Day Antipsychotics
314(13)
Current Pharmacotherapy for Schizophrenia
327(1)
Websites for Further Information
328(1)
Bibliography
328(5)
Antidepressants and Mood Stabilizers
333(33)
Biochemical Hypotheses of Affective Disorders
334(5)
Pharmacotherapy for Depression
339(14)
Pharmacotherapy in Mania and Bipolar Illnesses
353(6)
Nondrug Treatments for Depression
359(1)
Websites for Further Information
360(1)
Bibliography
360(6)
Pharmacotherapy for Miscellaneous Mental Disorders
366(41)
Disorders in Children
366(14)
Parkinson's Disease
380(4)
Tourette's Syndrome
384(1)
Epilepsy
385(4)
Geriatric Psychopharmacology
389(5)
Sexual Dysfunction
394(2)
Eating Disorders
396(2)
Websites for Further Information
398(1)
Bibliography
398(9)
Drug Name Index 407(2)
Index 409

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