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Greenspan's Basic & Clinical Endocrinology: Eighth Edition,9780071440110
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Greenspan's Basic & Clinical Endocrinology: Eighth Edition

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Edition:
8th
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9780071440110

ISBN10:
0071440119
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Paperback
Pub. Date:
1/19/2007
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McGraw-Hill Medical
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Summary

Endocrinology's #1 single-source reference updated to reflect the latest diagnostic testing and important new approaches to medical managementA Doody's Core Title ESSENTIAL PURCHASE!5 STAR DOODY'S REVIEW! "This book, one of the best endocrine textbooks, manages to be comprehensive but not overwhelming. Since various aspects of clinical endocrinology have changed in recent years, a new edition is certainly warranted. I would recommend this book to anyone with an interest in endocrinology."--Doody's Review ServiceBasic & Clinical Endocrinology,8e is a concise, single-source reference for the entire field of clinical endocrinology and the underlying basic science. Richly illustrated with 330 illustrations, this trusted guide is written by clinicians and researchers drawn largely from the University of California, San Francisco, one of the nation's most respected endocrine divisions.

Author Biography

David G. Gardner, MD, Professor of Medicine, Department of Medicine and Metabolic Research Unit, University of California, San Francisco.

Dolores Shoback, MD, Professor of Medicine, University of California, San Francisco.

Table of Contents

Authorsp. x
Prefacep. xiv
Introduction to Endocrinologyp. 1
The Endocrine Systemp. 2
Hormones: Endocrine, Paracrine, Autocrine, Juxtacrine, & Intracrine Actionsp. 3
Endocrine Organsp. 3
Target Organsp. 3
Hormone Receptorsp. 3
Chemical Composition of Hormonesp. 3
Relationships between Hormones & Other Signaling Moleculesp. 4
Neurotransmitters & Hormonesp. 4
Vitamins & Hormonesp. 5
Eicosanoids: Prostaglandins & Related Compoundsp. 5
Metabolitesp. 6
Oncogenes & Hormonesp. 6
The Immune System & Hormonesp. 6
Modulation of Hormone Levelsp. 6
Regulation of Hormone Productionp. 6
Molecular Mechanisms Regulating Hormone Releasep. 7
Hormone Transport in the Circulationp. 9
Transport of Hormones across the Membranep. 10
Metabolism & Elimination of Hormonesp. 10
Mechanisms of Hormone Actionp. 12
Hormone Receptorsp. 12
Hormone Bindingp. 14
Hormone Effects on Receptor Activityp. 14
Classes of Hormone Actionp. 14
Classification of Hormone Action by Receptor Typep. 14
Classification of Hormone Action by Ligand Typep. 15
Regulation of Hormone Responsivenessp. 16
Regulation of Receptor Levels & Activitiesp. 16
Hormone Responsiveness Is Regulated by Postreceptor Influencesp. 17
Combinatorial Interactions Influence Hormone Signaling in Different Waysp. 17
Selective Modulationp. 17
Evolution of the Endocrine Systemp. 18
The Origins of Regulatory Chemicals & the Metabolic Codep. 18
Evolution of Hormones & Receptorsp. 19
Evolution of Multiple Hormone Response Systemsp. 19
Evolution of Endocrine Glandsp. 19
Integrative Networksp. 20
Endocrine & Nervous System Relationships: Neuroendocrinologyp. 20
Actions of Hormonesp. 21
Fetal Developmentp. 21
Cell Growth & Cancerp. 21
Intermediary Metabolismp. 21
Mineral & Water Metabolismp. 21
Cardiovascular & Renal Functionp. 22
Skeletal Functionp. 22
Reproductive Functionp. 22
Immune Systemp. 22
Central Nervous Systemp. 23
Recent Advances in Technology & Endocrinologyp. 23
Sequencing the Human Genomep. 23
Genomics & Patterns of Transcriptionp. 23
Proteomicsp. 23
Manipulating the Genomep. 24
RNA Interference (RNAi)p. 24
Stem Cellsp. 24
Molecular Basis of Genetic Endocrine Diseasep. 25
Disorders of the Endocrine Systemp. 25
Endocrine Hypofunctionp. 26
Endocrine Hyperfunctionp. 27
Defects in Sensitivity to Hormonesp. 27
Syndromes of Hormone Excess Due to Exogenous Hormonep. 29
Nonendocrine Problems Associated with Endocrine Diseasep. 29
Approach to the Patient with Endocrine Diseasep. 29
History & Physical Examinationp. 29
Laboratory Studiesp. 29
Screening for Endocrine Diseasesp. 32
Treatment of Endocrine Diseasesp. 32
Uses of Hormones & Selective Modulators in Therapy of Nonendocrine Diseasep. 33
Mechanisms of Hormone Actionp. 35
Receptorsp. 36
Neurotransmitter & Peptide Hormone Receptorsp. 37
G Protein-Coupled Receptorsp. 37
G Protein Transducersp. 39
Effectorsp. 39
Disorders of G Proteins and G Protein-Coupled Receptorsp. 41
Growth Factor Receptorsp. 44
Cytokine Receptorsp. 47
Guanylyl Cyclase-Linked Receptorsp. 47
Nuclear Action of Peptide Hormonesp. 49
Nuclear Receptorsp. 49
Steroid Receptor Familyp. 49
Thyroid Receptor Familyp. 52
Nongenomic Effects of the Steroid Hormonesp. 56
Steroid & Thyroid Hormone Receptor Resistance Syndromesp. 57
Endocrine Autoimmunityp. 59
Basic Immune Components & Mechanismsp. 60
Immune Recognition & Responsep. 61
Tolerancep. 64
Autoimmunity Is Multifactorialp. 69
Genetic Factors in Autoimmunityp. 69
Environmental Factors in Autoimmunityp. 70
Single Gland Autoimmune Syndromesp. 70
Autoimmune Aspects of Thyroid Diseasep. 71
Autoimmune Aspects of Type 1 Diabetesp. 73
Autoimmune Aspects of Other Endocrinopathiesp. 75
Autoimmune Polyglandular Syndromesp. 76
Autoimmune Polyglandular Syndrome I (APS-I)p. 77
Autoimmune Polyglandular Syndrome II (APS-II)p. 78
Management of Autoimmune Polyglandular Syndromesp. 78
Poems Syndrome (Osteosclerotic Myeloma)p. 79
Evidence-Based Endocrinology & Clinical Epidemiologyp. 80
Clinical Epidemiologyp. 80
Diagnostic Testing: Test Characteristicsp. 80
An Approach to Diagnosis in Practicep. 86
Clinical Epidemiologic Principles Applied to Treatment Decisionsp. 88
Decision Analysisp. 89
Other Aspects of Clinical Epidemiologyp. 93
Evidence-Based Endocrinologyp. 93
Translation of the Clinical Problem into Answerable Questionsp. 93
Finding the Best Evidencep. 96
Appraising the Evidence for Its Validity & Usefulnessp. 96
Applying the Results in Practice & Evaluating Performancep. 97
Hypothalamus & Pituitary Glandp. 101
Hypothalamic Hormonesp. 106
Anterior Pituitary Hormonesp. 113
Adrenocorticotropic Hormone & Related Peptidesp. 113
Growth Hormonep. 114
Prolactinp. 118
Thyrotropinp. 120
Gonadotropins: Luteinizing Hormone & Follicle-Stimulating Hormonep. 121
Endocrinologic Evaluation of the Hypothalamic-Pituitary Axisp. 123
Evaluation of Adrenocorticotropic Hormone (ACTH)p. 123
Evaluation of Growth Hormone (GH)p. 127
Evaluation of Prolactin (PRL)p. 127
Evaluation of Thyroid-Stimulating Hormone (TSH)p. 127
Evaluation of LH & FSHp. 127
Problems in Evaluation of the Hypothalamic-Pituitary Axisp. 128
Effects of Pharmacologic Agents on Hypothalamic-Pituitary Functionp. 128
Endocrine Tests of Hypothalamic-Pituitary Functionp. 129
Neuroradiologic Evaluationp. 129
Pituitary & Hypothalamic Disordersp. 131
Empty Sella Syndromep. 132
Hypothalamic Dysfunctionp. 133
Hypopituitarismp. 134
Pituitary Adenomasp. 140
Posterior Pituitary (Neurohypophysis)p. 157
Review of Normal Anatomy & Physiologyp. 157
Vasopressin Insufficiency: Diabetes Insipidusp. 160
Excess Vasopressin: Syndrome of Inappropriate Antidiuretic Hormone (SIADH)p. 165
Oxytocinp. 169
Parturitionp. 169
Lactationp. 169
Growthp. 171
Normal Growthp. 171
Intrauterine Growthp. 171
The Placentap. 172
Classic Hormones of Growth & Fetal Growthp. 172
Growth Factors & Oncogenes in Fetal Growthp. 172
Insulin-Like Growth Factors, Receptors, & Binding Proteinsp. 172
Insulinp. 172
Epidermal Growth Factorp. 173
Fetal Origins of Adult Diseasep. 174
Postnatal Growthp. 174
Measurement of Growthp. 183
Skeletal (Bone) Agep. 186
Disorders of Growthp. 186
Short Stature Due to Nonendocrine Causesp. 186
Short Stature Due to Endocrine Disordersp. 193
Diagnosis of Short Staturep. 204
Tall Stature Due to Nonendocrine Causesp. 205
Tall Stature Due to Endocrine Disordersp. 206
The Thyroid Glandp. 209
Embryology, Anatomy, & Histologyp. 210
Physiologyp. 210
Structure & Synthesis of Thyroid Hormonesp. 210
Iodine Metabolismp. 212
Thyroid Hormone Synthesis & Secretionp. 212
Abnormalities in Thyroid Hormone Synthesis & Releasep. 216
Metabolism of Thyroid Hormonesp. 219
Control of Thyroid Function & Hormone Actionp. 221
Physiologic Changes in Thyroid Functionp. 229
Thyroid Autoimmunityp. 231
Tests of Thyroid Functionp. 232
Tests of Thyroid Hormones in Bloodp. 232
Assessment of Thyroid Iodine Metabolism & Biosynthetic Activityp. 236
Thyroid Imagingp. 237
Thyroid Ultrasonography & Other Imaging Techniquesp. 238
Thyroid Biopsyp. 238
Test of Peripheral Thyroid Hormone Actionsp. 239
Measurement of Thyroid Autoantibodiesp. 239
Disorders of the Thyroidp. 239
Hypothyroidismp. 240
Hyperthyroidism & Thyrotoxicosisp. 248
Thyroid Hormone Resistance Syndromesp. 260
Nontoxic Goiterp. 260
Thyroiditisp. 263
Effects of Ionizing Radiation on the Thyroid Glandp. 266
Thyroid Nodules & Thyroid Cancerp. 267
Metabolic Bone Diseasep. 281
Cellular & Extracellular Calcium Metabolismp. 281
Parathyroid Hormonep. 282
Calcitoninp. 288
Vitamin Dp. 288
How Vitamin D & PTH Control Mineral Homeostasisp. 297
Medullary Carcinoma of the Thyroid (MCT)p. 297
Hypercalcemiap. 299
Disorders Causing Hypercalcemiap. 300
Treatment of Hypercalcemiap. 310
Hypocalcemiap. 310
Causes of Hypocalcemiap. 312
Treatment of Hypocalcemiap. 316
Bone Anatomy & Remodelingp. 317
Functions of Bonep. 317
Structure of Bonep. 317
Bone Remodelingp. 319
Osteoporosisp. 320
Treatment of Osteoporosisp. 325
Glucocorticoid-Induced Osteoporosisp. 330
Osteomalacia & Ricketsp. 331
Nephrotic Syndromep. 334
Hepatic Osteodystrophyp. 335
Drug-Induced Osteomalaciap. 335
Hypophosphatemic Disordersp. 335
Calcium Deficiencyp. 337
Primary Disorders of the Bone Matrixp. 337
Inhibitors of Mineralizationp. 338
Paget's Disease of Bone (Osteitis Deformans)p. 338
Renal Osteodystrophyp. 342
Glucocorticoids & Adrenal Androgensp. 346
Embryology & Anatomyp. 346
Biosynthesis of Cortisol & Adrenal Androgensp. 348
Circulation of Cortisol & Adrenal Androgensp. 354
Metabolism of Cortisol & Adrenal Androgensp. 354
Biologic Effects of Adrenal Steroidsp. 356
Glucocorticoidsp. 356
Adrenal Androgensp. 363
Laboratory Evaluationp. 363
Disorders of Adrenocortical Insufficiencyp. 367
Primary Adrenocortical Insufficiency (Addison's Disease)p. 367
Secondary Adrenocortical Insufficiencyp. 372
Diagnosis of Adrenocortical Insufficiencyp. 373
Treatment of Adrenocortical Insufficiencyp. 375
Prognosis of Adrenocortical Insufficiencyp. 378
Cushing's Syndromep. 378
Hirsutism & Virilismp. 390
Incidental Adrenal Massp. 390
Glucocorticoid Therapy for Nonendocrine Disordersp. 391
Endocrine Hypertensionp. 396
Hypertension of Adrenal Originp. 396
Synthesis, Metabolism, & Action of Mineralocorticoid Hormonesp. 396
Pathogenesis of Mineralocorticoid Hypertensionp. 398
Aldosterone & the Heartp. 398
Primary Aldosteronismp. 399
Syndromes Due to Excess Deoxycorticosterone Productionp. 404
Cushing's Syndromep. 406
Pseudohyperaldosteronismp. 406
Type II Pseudohypoaldosteronism (Arnold-Healy-Gordon Syndrome)p. 409
Hypertension of Renal Originp. 410
The Renin-Angiotensin Systemp. 410
The Renin-Angiotensin System & Hypertensionp. 413
Other Hormone Systems & Hypertensionp. 417
Insulinp. 417
Natriuretic Peptidesp. 418
Nitric Oxidep. 418
Endothelinp. 419
Kallikrein-Kinin Systemp. 419
Other Hormones & Autacoidsp. 419
Sympathetic Nervous Systemp. 419
Adrenal Medulla & Paragangliap. 421
Historyp. 422
Anatomyp. 423
Hormones of the Adrenal Medullap. 424
Catecholaminesp. 424
Other Hormones Secreted by the Adrenal Medullap. 435
Disorders of Adrenal Medullary Functionp. 435
Adrenal Medullary Hypofunction (Epinephrine Deficiency)p. 435
Adrenal Medullary Hyperfunctionp. 437
Pheochromocytomap. 437
Testesp. 470
Anatomy & Structure-Function Relationshipsp. 470
Testesp. 470
Accessory Structuresp. 472
Physiology of the Male Reproductive Systemp. 472
Gonadal Steroidsp. 472
Control of Testicular Functionp. 475
Evaluation of Male Gonadal Functionp. 476
Clinical Evaluationp. 476
Laboratory Tests of Testicular Functionp. 477
Pharmacology of Drugs Used to Treat Male Gonadal Disordersp. 479
Androgensp. 479
Gonadotropinsp. 481
Gonadotropin-Releasing Hormonep. 481
Clinical Male Gonadal Disordersp. 481
Klinefelter's Syndrome (XXY Seminiferous Tubule Dysgenesis)p. 482
Bilateral Anorchia (Vanishing Testes Syndrome)p. 484
Leydig Cell Aplasiap. 485
Cryptorchidismp. 485
Noonan's Syndrome (Male Turner's Syndrome)p. 487
Myotonic Dystrophyp. 488
Adult Seminiferous Tubule Failurep. 488
Adult Leydig Cell Failure (Andropause)p. 490
Male Infertilityp. 490
Erectile Dysfunction (Impotence)p. 493
Gynecomastiap. 495
Testicular Tumorsp. 497
Female Reproductive Endocrinology & Infertilityp. 502
Embryology & Anatomyp. 502
Ovarian Steroidogenesisp. 505
Physiology of Folliculogenesis & the Menstrual Cyclep. 508
Menstrual Disturbancesp. 517
Amenorrheap. 517
Hypothalamic Amenorrheap. 520
Pituitary Amenorrheap. 522
Ovarian Amenorrheap. 524
Anovulationp. 527
Obesityp. 534
Outflow Tract Disordersp. 536
Menopausep. 537
Oocyte Depletionp. 538
Endocrine System Changes with Agingp. 539
Menopausal Consequencesp. 540
Infertilityp. 543
Diagnosis of Infertilityp. 543
Management of the Infertile Couplep. 545
Contraceptionp. 546
Oral Contraceptivesp. 546
Contraception: Long-Acting Contraceptivesp. 552
Emergency Contraceptionp. 559
Disorders of Sexual Determination & Differentiationp. 562
Normal Sex Differentiationp. 562
Testicular & Ovarian Differentiationp. 568
Psychosexual Differentiationp. 574
Atypical Sex Differentiationp. 574
Klinefelter's Syndrome and Its Variants: Seminiferous Tubule Dysgenesisp. 574
Syndrome of Gonadal Dysgenesis: Turner's Syndrome & Its Variantsp. 577
Individuals with Both Ovarian and Testicular Tissue (True Hermaphroditism)p. 583
Female Pseudohermaphroditismp. 584
P450 Aromatase Deficiencyp. 590
Maternal Androgens & Progestogensp. 591
Male Pseudohermaphroditismp. 591
Unclassified Forms of Abnormal Sexual Development in Malesp. 602
Unclassified Forms of Abnormal Sexual Development in Femalesp. 603
Management of Patients with Intersex Problemsp. 603
Pubertyp. 611
Physiology of Pubertyp. 611
Delayed Puberty or Absent Puberty (Sexual Infantilism)p. 620
Precocious Puberty (Sexual Precocity)p. 631
The Endocrinology of Pregnancyp. 641
Conception & Implantationp. 641
Fetal-Placental-Decidual Unitp. 642
Polypeptide Hormonesp. 645
Steroid Hormonesp. 646
Maternal Adaptation to Pregnancyp. 647
Fetal Endocrinologyp. 651
Endocrine Control of Parturitionp. 652
Endocrinology of the Puerperiump. 653
Endocrine Disorders & Pregnancy Pituitary Disordersp. 655
Pregnancy & Breast Cancerp. 656
Hypertensive Disorders of Pregnancyp. 657
Hyperthyroidism in Pregnancyp. 658
Hypothyroidism in Pregnancyp. 659
Pancreatic Hormones & Diabetes Mellitusp. 661
The Endocrine Pancreasp. 662
Anatomy & Histologyp. 662
Hormones of the Endocrine Pancreasp. 662
Diabetes Mellitusp. 672
Classificationp. 672
Diabetes Mellitusp. 673
Diabetesp. 675
Other Specific Types of Diabetesp. 677
Clinical Features of Diabetes Mellitusp. 680
Diabetesp. 681
Diabetesp. 681
Urinalysisp. 682
Blood Glucose Testingp. 683
Serum Ketone Determinationsp. 685
Glycated Hemoglobin Assaysp. 685
Lipoproteins in Diabetesp. 686
Oral Glucose Tolerance Testp. 687
Insulin Levelsp. 687
Intravenous Glucose Tolerance Testp. 687
Dietp. 692
Agents for the Treatment of Hyperglycemiap. 693
Insulinp. 701
Steps in the Management of the Diabetic Patientp. 707
Hypoglycemiap. 713
Comap. 715
Specific Chronic Complications of Diabetes Mellitusp. 727
Diabetic Patients Regulated by Diet Alonep. 734
Diabetic Patients Taking Oral Hypoglycemic Agentsp. 734
Diabetic Patients Taking Insulinp. 734
Hypoglycemic Disordersp. 748
Pathophysiology of the Counterregulatory Response to Neuroglycopeniap. 748
Classification of Hypoglycemic Disordersp. 753
Clinical Presentation of Hypoglycemiap. 754
Specific Hypoglycemic Disordersp. 755
Symptomatic Fasting Hypoglycemia with Hyperinsulinismp. 755
Symptomatic Fasting Hypoglycemia without Hyperinsulinismp. 762
Nonfasting Hypoglycemia (Reactive Hypoglycemia)p. 763
Congenital Hyperinsulinismp. 764
Disorders of Lipoprotein Metabolismp. 770
Atherosclerosisp. 770
Overview of Lipid Transportp. 771
Differentiation of Disorders of Lipoprotein Metabolismp. 775
Clinical Descriptions of Primary & Secondary Disorders of Lipoprotein Metabolismp. 777
Primary Hypertriglyceridemiap. 777
Secondary Hypertriglyceridemiap. 781
Familial Hypercholesterolemiap. 783
Familial Combined Hyperlipidemiap. 784
Lp(a) Hyperlipoproteinemiap. 784
Familial Ligand-Defective Apo Bp. 784
Cholesterol 7-[alpha]-Hydroxylase Deficiencyp. 784
Hypothyroidismp. 784
Nephrosisp. 784
Immunoglobulin Disordersp. 785
Anorexia Nervosap. 785
Cholestasisp. 785
Primary Hypolipidemia Due to Deficiency of High-Density Lipoproteinsp. 785
Primary Hypolipidemia Due to Deficiency of Apo B-Containing Lipoproteinsp. 787
The Lipodystrophiesp. 788
Rare Disordersp. 788
Treatment of Hyperlipidemiap. 789
Bile Acid Sequestrantsp. 791
Niacin (Nicotinic Acid)p. 792
Fibric Acid Derivativesp. 792
HMG-CoA Reductase Inhibitorsp. 793
Cholesterol Absorption Inhibitorsp. 793
Combined Drug Therapyp. 794
Obesity & Overweightp. 796
Clarification of Uncertainties Regarding the Pathogenesis of Obesityp. 807
Survey of Treatment Approaches & Their Efficacyp. 808
Diet & Exercisep. 808
Exercisep. 810
Surgical Treatment of Obesityp. 810
Pharmacologic Therapiesp. 810
Other Conditions Affected by Treatment of Obesity or Overweightp. 813
Type 2 Diabetes Mellitusp. 813
Hyperlipidemiap. 813
Polycystic Ovarian Syndromep. 813
Hypertensionp. 813
Gallstonesp. 815
Sleep Apneap. 815
Osteoarthritis & Other Weight-Sensitive Statesp. 815
A Systematic Approach to the Treatment of Obesityp. 815
Humoral Manifestations of Malignancyp. 817
Ectopic Hormone & Receptor Syndromesp. 817
Hypercalcemia of Malignancyp. 818
Ectopic Cushing's Syndromep. 821
Syndrome of Inappropriate Anridiuretic Hormone Secretionp. 824
Non-Islet Cell Tumors & Hypoglycemiap. 825
Other Hormones Secreted by Tumorsp. 826
Oncogenic Osteomalaciap. 827
Gut Hormonesp. 828
Multiple Endocrine Neoplasiap. 831
Multiple Endocrine Neoplasia Type 1 (Men 1)p. 831
Multiple Endocrine Neoplasia Type 2 (Men 2)p. 836
Other Disorders Characterized by Multiple Endocrine Organ Involvementp. 841
Geriatric Endocrinologyp. 844
Thyroid Function & Diseasep. 844
Disorders of the Thyroid Glandp. 845
Carbohydrate Intolerance & Diabetes Mellitusp. 849
Aging & the Physiology of Carbohydrate Intolerancep. 849
Diabetes Mellitusp. 849
Nonketotic Hyperosmolar Comap. 852
Osteoporosis & Calcium Homeostasisp. 853
Osteoporosisp. 853
Hyperparathyroidismp. 860
Changes in Water Balancep. 861
Hypernatremiap. 861
Hyponatremiap. 861
Hyporeninemic Hypoaldosteronismp. 862
Glucocorticoids & Stressp. 862
Disorders of the Hypothalamic-Pituitary-Adrenal Axisp. 862
Changes in Reproductive Function in Menp. 863
Benign Prostatic Hyperplasiap. 865
Endocrine Emergenciesp. 868
Myxedema Comap. 868
Thyroid Stormp. 870
Thyrotoxic Periodic Paralysisp. 871
Amiodarone-Induced Thyrotoxicosisp. 872
Acute Adrenal Insufficiencyp. 873
Pituitary Apoplexyp. 874
Diabetic Ketoacidosisp. 875
Nonketotic Hyperosmolar Comap. 879
Hypercalcemic Crisisp. 882
Acute Hypocalcemiap. 884
Hyponatremiap. 886
Diabetes Insipidusp. 889
AIDS Endocrinopathiesp. 894
Thyroid Disordersp. 894
Adrenal Disordersp. 896
Bone & Mineral Disordersp. 898
Gonadal Disordersp. 900
Pituitary Disordersp. 901
Lipid Disordersp. 904
Conclusionp. 908
Endocrine Surgeryp. 911
The Thyroid Glandp. 911
Embryology & Anatomyp. 911
Developmental Thyroid Abnormalitiesp. 911
Hyperthyroidismp. 912
Thyroiditisp. 913
Goiter (Nontoxic)p. 913
Thyroid Nodulesp. 913
Thyroid Cancerp. 914
Conduct of Thyroidectomyp. 916
The Parathyroid Glandp. 917
Embryology & Anatomyp. 917
Primary Hyperparathyroidism (PHPT)p. 919
Persistent & Recurrent Primary Hyperparathyroidismp. 922
Secondary Hyperparathyroidismp. 922
Special Consideration: Familial Hyperparathyroidismp. 923
Complications of Parathyroid Surgeryp. 923
The Adrenal (Suprarenal) Glandp. 923
Embryology & Anatomyp. 923
Primary Hyperaldosteronismp. 924
Hypercortisolismp. 924
Adrenal Cortical Carcinomap. 925
Sex Steroid Excessp. 925
Pheochromocytomap. 925
Adrenal Incidentalomap. 926
Technique of Adrenalectomyp. 927
The Endocrine Pancreasp. 927
Embryology & Anatomyp. 927
Insulinomap. 927
Gastrinoma (Zollinger-Ellison Syndrome)p. 929
VIPoma (Verner-Morrison) Syndromep. 930
Glucagonomap. 930
Somatostatinomap. 930
Nonfunctioning Pancreatic Tumorsp. 930
Normal Hormone Reference Rangesp. 933
Indexp. 958
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