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9781405107792

Dermatopathology

by ; ;
  • ISBN13:

    9781405107792

  • ISBN10:

    1405107790

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2011-07-01
  • Publisher: Wiley-Blackwell
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Summary

Dermatopathology is the microscopic study of human skin in health and disease. Whilst some skin diseases can be diagnosed on purely clinical grounds, many require confirmation from histological study of skin biopsy samples. Trainees in both dermatology and pathology must learn dermatopathology as part of their specialist training. Whilst there are a number of large reference works, these are not suitable for the trainee as they assume too much knowledge. The book will be well illustrated (as this is a very visual subject) and will be didactic in nature as it aims to teach the skills of pattern recognition and to explain how the visible features in a histological slide correlate to disease. Section one explains the structure and function of normal human skin from the anatomical point of view. Section two covers techniques of obtaining the biopsy sample and preparing the histological slide, staining and fixing the specimen etc. Section three goes through all the definitions of each type of microscopic feature such as hyperkeratosis, exocytosis, pleomorphism etc clearly pointing out the relevant points on a histological slide. Section four goes through each skin disease and shows how the key diagnostic features can be identified in order to confirm a diagnosis.

Author Biography

Dr Donald MacDonald, formerly Department of Dermatology, St Thomas and Guy's Hospital, London

Dr Mohamed Ben-Gashir, Histopathology Department, University College London, London

Dr Alistair Robson, Department of Dermatopathology, St Thomas Hospital, London

Table of Contents

Forewords
Introduction
List of Contents
List of Abbreviations
Normal Histology
Normal Skin
Salivary Gland
The Nail
Striated muscle (skeletal muscle
Cartilage
Bone
Morphology of individual inflammatory cells
Histological definitions
Histopathology specimens
Biopsy techniques and indications
Specimen preparation
Histochemistry in dermatopathology
Immunocytochemistry in dermatopathology
Physical effects and artefacts
In vivo physical effects and artefacts
Differential Diagnosis
Artefacts etc associated with tissue processing
Congenital and inherited diseases
Bullous Diseases
Inflammatory disorders
Spongiotic
Psoriasiform
Lichenoid
Connective tissue disorders
Dermal inflammation and perforating disorders
Follicular disorders and alopecia
Infections and infestations
Viral infections
Non-granulomatous cutaneous bacterial infections
Superficial fungal infection
Arthropod infestations
Helminth infestations
Granulomatous inflammation
Panniculitis
Vasculopathies
Metabolic diseases
Disorders of pigmenttion
Cysts and sinuses
Tumours of the epidermis
Benign
Premalignant and malignant
Adnexal tumours
Hair follicle derived tumours
Sebaceous tumours
Lesions of the sweat apparatus
Malignancy in adnexal tumours
Melanocytic lesions
Mesenchymal lesions
Tumours and proliferations of fibrous tissue - a heterogenous group
Tumours of adipose tissue
Muscle tumours
Neuroectodermal and neuroendocrine tumours
Tumours of bone and cartilage
Vascular proliferations and tumours
Benign and malignant lymphoid infiltrates
T-cell lymphoma
B-cell lymphoma
'Reactive' lymphocytic infiltrates
Histocytic proliferations
Cutaneous metastases
Differential diagnosis in dermatopathology
Differential diagnosis of skin disease
Differential diagnosis of 'normal skin'
Index
Table of Contents provided by Publisher. All Rights Reserved.

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