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9780470693148

Systematic Reviews in Health Care: Meta-Analysis in Context, 2nd Edition

by ; ;
  • ISBN13:

    9780470693148

  • ISBN10:

    0470693142

  • Format: eBook
  • Copyright: 2008-04-01
  • Publisher: BMJ Books
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Summary

The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.

Table of Contents

Foreword
Introduction
Rationale, potentials and promise of systematic review
Systematic reviews of controlled trials
Principles and procedures
Problems and limitations
Identifying randomised trials
Assessing the quality of controlled clinical trials
Obtaining individual patient data from randomised controlled trials
Assessing the quality of reports of systematic reviews
Investigating variability within and between studies
Going beyond the grand mean
Why and how sources of heterogeneity should be investigated
Analysing the relationship between treatment benefit and underlying risk
Investigating and dealing with publication and other biases
Systematic review of observational studies
Systematic reviews of observational studies
Systematic reviews of prognostic studies
Systematic reviews of evaluations of diagnostic studies
Statistical method and computer software
Statistical methods of examining heterogeneity and combining results from several studies
Choice of effect measure for binary outcomes
Meta-analysis software
Meta-analysis in STATA
Using systematic reviews in practice
Applying the results of systematic reviews at the bedside
Numbers needed to treat derived from meta-analysis: pitfalls and cautions
Using systematic reviews in clinical guidelines development
Using systematic reviews for evidence based policy making
Using systematic reviews for economic evaluation
Using systematic reviews and registers of ongoing trials for scientific and ethical trial design
The Cochrane Collaboration
The Cochrane Collaboration in the 20th Century
The Cochrane Collaboration in the 21st Century: ten challenges and one reason whey they must be met
Future challenges
Unresolved issues and future developments
Table of Contents provided by Publisher. All Rights Reserved.

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