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9783527317165

Proteomics of the Nervous System

by ;
  • ISBN13:

    9783527317165

  • ISBN10:

    3527317163

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2008-11-01
  • Publisher: Blackwell Pub
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List Price: $189.95

Summary

Covering applications in both biomedical and basic research, this is the first book to combine the cutting-edge technology of proteomics with the highly important field of neuroscience.This ready reference provides the theoretical foundations, protocols for a number of key proteomic techniques, and case studies of the application of proteomics to brain and neural research.Helping lead the fight against the life-threatening and debilitating diseases of the nervous system, such as multiple sclerosis, Alzheimer's, Parkinson's, Epilepsy and many others, Proteomics of the Nervous Systemis an essential read in this rapidly growing subject.

Author Biography

Professor Pfeiffer has been professor in the University of Connecticut since 1969, and has carried out research in many different countries including France, Germany and Japan. He has served as the president of the International Society for Developmental Neurobiology, and as a member of the council of the International Society for Neurochemistry. He is a member of numerous scientific societies, and is on the editorial boards of many journals including the Journal of Neuroscience Research. He is author of over 100 scientific publications.

Dr Nothwang carried out his PhD in the Jacque Monod Institute in Paris, France, before carrying out postdoctoral work in Tokushima, Japan, and Freiburg, Germany. Since 2001 he has been working as a research associate in the University of Kaiserslautern, Germany, where his work focuses on proteomic analyses of the nervous system.

Table of Contents

Basic Methods in Protein Analysis Protein Purification
Common Methods in Proteomics
Proteomic Technologies for the Analysis of Protein Complexes
Analysis of Membrane Protein Complexes by Blue native PAGE
Current Approaches to Protein Structure Analysis
APPLICATION TO BASIC NEUROSCIENCE Primer to Proteins Underlying Cellular Complexity and Function in the Nervous System
Proteome Analysis of Plasma Membranes
Proteome Analysis of Synaptic Vesicles
Proteomics Analysis of the Synapse
Peptidomics in the Nervous System
Analysis of Posttranslational Modifications
BIOMEDICAL RESEARCH Proteomics of Neurodegenerative Disorders
The Search for Protein Biomarkers of Neurobiological Diseases
Redox-Proteomics: Applications to Age-related Neurodegenerative Disorders
Paranode Structure and Function
Appendix
Table of Contents provided by Publisher. All Rights Reserved.

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