Foreword | p. x |
Preface | p. xiii |
Acknowledgments | p. xvi |
Introduction | p. xvii |
From Genes to Human Beings | p. 1 |
Mendel and the Laws of Heredity | p. 1 |
Cells, Chromosomes, and Sex | p. 6 |
Discovering and Mapping Genes | p. 10 |
From Genotype to Phenotype | p. 14 |
Stem Cells and Development | p. 17 |
Mutations | p. 20 |
Making Blood in the Lab | p. 21 |
The Evolution of the Human Genome | p. 30 |
The Origins of the Genome | p. 31 |
Traces of the Early Evolution of Animals | p. 37 |
Molecular Clocks | p. 44 |
Comparing the Chimpanzee and Human Genomes | p. 47 |
The Search for the Earliest Hominid | p. 48 |
The Evolution of the Human Brain | p. 54 |
Mitochondrial Eve and Y-Chromosomal Adam | p. 61 |
Populating the Globe | p. 70 |
What Happened to the Neanderthals? | p. 71 |
Using Genetics to Solve Ancient Mysteries and Modern Crimes | p. 81 |
Ötzi's Granddaughter | p. 82 |
The Origins of the Basques | p. 85 |
Making a Pedigree | p. 90 |
The Heirs of Thomas Jefferson | p. 92 |
The Grave of Jesse James | p. 95 |
The Fate of Anastasia, Grand Duchess of Russia | p. 98 |
The Genetics of Health and Disease | p. 104 |
Finding Disease Genes | p. 106 |
Multifactorial Diseases | p. 110 |
Diagnosis and Genetic Counseling | p. 113 |
Learning to Repair Defective Genes | p. 117 |
The Genetics of Cancer | p. 120 |
Stem Cells and Cancer | p. 123 |
Mary-Claire King: Cancer Pioneer and Activist | p. 125 |
Chernobyl and Its Impact on the Human Genome | p. 130 |
Genes of the Adaptive Immune System | p. 134 |
Pharmacogenetics and the Development of Individualized Medicine | p. 139 |
The Genetics of Behavior, Human Diversity, and Society | p. 142 |
The Science and Politics of Human Diversity | p. 143 |
Evolutionary Psychology | p. 148 |
Twin Studies and the Genetics of IQ | p. 156 |
The Genetics of Cognitive Disorders | p. 160 |
Kim Peek and the Savants | p. 166 |
Human Adaptation and Competition between Societies | p. 169 |
Conclusion: A Look into the Future: The Genetic Engineering of Human Beings? | p. 174 |
Chronology | p. 179 |
Glossary | p. 193 |
Further Resources | p. 203 |
Index | p. 220 |
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