Science of Clinical Oncology | p. 1 |
Biology and Cancer | |
Molecular Tools in Cancer Research | p. 3 |
Intracellular Signaling | p. 21 |
The Cellular Microenvironment and Metastases | p. 33 |
Control of the Cell Cycle | p. 49 |
Cell Life and Death | p. 67 |
Cancer Immunology | p. 77 |
Stem Cells, Cell Differentiation, and Cancer | p. 95 |
Vascular and Interstitital Biology of Tumors | p. 105 |
Genesis of Cancer | |
Environmental Factors | p. 125 |
DNA Damage Response Pathways and Cancer | p. 139 |
Viruses and Human Cancer | p. 153 |
Genetic Factors: Hereditary Cancer Predisposition Syndromes | p. 171 |
Genetic Factors: Finding Cancer Susceptibility Genes | p. 193 |
Progressing from Gene Mutations to Cancer | p. 207 |
Immunodeficiency and Cancer | p. 223 |
Diagnosing Cancer: Pathology and Laboratory Medicine | |
Principles of Oncologic Surgical Pathology | p. 233 |
Flow Cytometry in Oncologic Diagnosis | p. 241 |
Conventional and Molecular Cytogenetics of Neoplasia | p. 249 |
Molecular Diagnostics | p. 265 |
Biomarkers for Cancer Diagnostics | p. 277 |
Imaging | p. 283 |
Preventing and Treating Cancer | |
Biostatistics and Bioinformatlcs in Clinical Trials | p. 309 |
Structures Supporting Cancer Clinical Trials | p. 327 |
Economic Analysis of Cancer Treatment | p. 337 |
Use of Epidemiology in Oncology | p. 343 |
Cancer Prevention, Screening, and Early Detection | p. 361 |
Nicotine Dependence: Current Treatments and Future Directions | p. 397 |
Surgical Interventions in Cancer | p. 407 |
Basics of Radiation Therapy | p. 417 |
Systemic Therapy | p. 449 |
Principles of Molecularly Targeted Therapy: Present and Future | p. 485 |
Hematopoietic Stem Cell Transplantation | p. 501 |
Gene Therapy in Oncology | p. 513 |
Therapeutic Antibodies and Immunologic Conjugates | p. 531 |
Complementary and Alternative Medicine | p. 545 |
Problems Common to Cancer and its Therapy | p. 563 |
Symptom Management and Palliative Care | |
Cancer Pain | p. 565 |
Rehabilitation of Individuals with Cancer | p. 579 |
Cachexia | p. 591 |
Nausea and Vomiting | p. 599 |
Oral Complications | p. 609 |
Alopecia and Cutaneous Complications | p. 625 |
Lymphedema | p. 641 |
Fatigue | p. 657 |
Caring for Patients at the End of Life | p. 665 |
Hematologic Problems | |
Disorders of Blood Cell Production in Clinical Oncology | p. 677 |
Diagnosis, Treatment, and Prevention of Cancer-Related Venous Thrombosis | p. 693 |
Infections | |
Infection in the Patient with Cancer | p. 717 |
Metabolic and Paraneoplastic Syndromes | |
Hypercalcemia | p. 739 |
Hyponatremia | p. 749 |
Tumor Lysis Syndrome | p. 759 |
Paraneoplastic Neurologic Syndromes | p. 767 |
Surgical Problems | |
Establishing and Maintaining Vascular Access | p. 779 |
Acute Abdomen, Bowel Obstruction, and Fistula | p. 792 |
Local Effects of Cancer and Its Metastasis | |
Superior Vena Cava Syndrome | p. 803 |
Spinal Cord Compression | p. 815 |
Brain Metastases and Neoplastic Meningitis | p. 827 |
Bone Metastases | p. 845 |
Lung Metastases | p. 873 |
Liver Metastases | p. 885 |
Effusions | p. 925 |
Complications of Therapy | |
Neurologic Complications | p. 945 |
Pulmonary Complications of Anticancer Treatment | p. 969 |
Cardiac Effects of Cancer Therapy | p. 983 |
Reproductive Complications | p. 999 |
Endocrine Complications | p. 1013 |
Second Malignant Neoplasms | p. 1023 |
Special Populations | |
Cancer in the Elderly: Biology, Prevention, and Treatment | p. 1039 |
Special Issues in Pregnancy | p. 1049 |
HIV-Associated Malignancies | p. 1061 |
Specific Malignancies | p. 1073 |
Cancer of the Central Nervous System | p. 1075 |
Eye, Orbit, and Adnexal Structures | p. 1137 |
Cancer of the Head and Neck | p. 1177 |
Melanoma | p. 1229 |
Nonmelanoma Skin Cancers: Basal Cell and Squamous Cell Carcinomas | p. 1253 |
Cancer of the Endocrine System | p. 1271 |
Cancer of the Lung: Non-Small Cell Lung Cancer | p. 1307 |
Tumors of the Pleura and Mediastinum | p. 1367 |
Cancer of the Esophagus | p. 1399 |
Cancer of the Stomach | p. 1431 |
Cancer of the Small Bowel | p. 1465 |
Colon Cancer | p. 1477 |
Cancer of the Rectum | p. 1535 |
Cancer of the Anal Canal | p. 1557 |
Liver and Bile Duct Cancer | p. 1569 |
Carcinoma of the Pancreas | p. 1595 |
Cancer of the Kidney | p. 1613 |
Carcinoma of the Bladder | p. 1635 |
Prostate Cancer | p. 1653 |
Cancer of the Penis | p. 1701 |
Testicular Cancer | p. 1713 |
Cancers of the Cervix, Vulva, and Vagina | p. 1745 |
Cancer of the Endometrium | p. 1793 |
Ovaries and Fallopian Tubes | p. 1827 |
Gestational Trophoblastic Disease | p. 1857 |
Cancer of the Breast | p. 1875 |
Sarcomas of Bone | p. 1945 |
Sarcomas of Soft Tissue | p. 2009 |
Carcinoma of Unknown Primary | p. 2057 |
Pediatric Solid Tumors | p. 2075 |
World Health Organization Classification of Hematologic Malignancies | p. 2131 |
Childhood Leukemia | p. 2139 |
Childhood Lymphoma | p. 2171 |
Acute Lymphocytic Leukemia in Adults | p. 2191 |
Acute Myeloid Leukemia in Adults | p. 2215 |
Myelodysplastic Syndromes | p. 2235 |
Myeloproliferative Disorders | p. 2261 |
Chronic Myeloid Leukemia | p. 2279 |
Chronic Lymphoid Leukemias | p. 2293 |
Hairy Cell Leukemia | p. 2309 |
Multiple Myeloma and Related Disorders | p. 2323 |
Hodgkin's Lymphoma | p. 2353 |
Non-Hodgkin's Lymphoma | p. 2371 |
Cutaneous T-Cell Lymphoma and Cutaneous B-Cell Lymphoma | p. 2405 |
Adult T-Cell Leukemia-Lymphoma | p. 2425 |
Index | p. 2443 |
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