Acute Coronary Syndromes A Handbook for Clinical Practice

by Bertrand, Michael; King, Spencer B.

• ISBN13: 9781405135016
• ISBN10: 1405135018
• Edition: 1st
• Format: Hardcover
• Copyright: 2006-03-20
• Publisher: Wiley-Blackwell

Summary

The management of non-ST segment elevation acute coronary syndromes (NSTE-ACS) has rapidly evolved over the last few years and many guidelines have been provided and already updated. This book is based on the latest ESC Guidelines and reports the current knowledge in NSTE-ACS, together with the most recent therapeutic options and the different strategies that can be applied according to the clinical status of patients. International experts address the different aspects of NSTE-ACS and bring useful information to clinicians, urgentists and surgeons involved in the difficult management of these patients. The ESC Education Series This book is part of the ESC Education Series. The series is designed to provide medical professionals with the latest information about the understanding, diagnosis and management of cardiovascular diseases. Where available, management recommendations are based on the established European Guidelines, which encompass the best techniques to use with each cardiac disease. Throughout the series, the leading international opinion leaders have been chosen to edit and contribute to the books. The information is presented in a succinct and accessible format with a clinical focus.

Author Biography

Michael Bertrand, Emeritus Professor of Cardiology, Lille Heart Institute, Lille, France

Dr Spencer King III, Fuqua Chair of Interventional Cardiolo, Fuqua institute, Atlanta, GA, USA

Table of Contents

List of contributors	viii
Preface	x
Section one: Epidemiology
Epidemiology of non-ST-segment elevation acute coronary syndromes	3	(8)
David Hasdai
Alexander Battler
Section two: Pathophysiology
Pathologic findings in acute coronary syndromes	11	(13)
Erling Falk
Vascular biology of acute coronary syndromes	24	(19)
Lina Badimon
Section three: Clinical aspects of ACS
Clinical aspects of acute coronary syndromes	43	(9)
Eugene McFadden
Circulating biomarkers for risk stratification	52	(13)
Christopher Heeschen
Section four: Investigation in ACS
Coronary angiography, angioscopy, and intravascular ultrasound in non-ST-segment elevation acute coronary syndromes	65	(13)
Eric Van Belle
Christophe Bauters
Francois Schiele
Michel E. Bertrand
New coronary imaging in acute coronary syndrome	78	(19)
Pim J. de Feyter
Evelyne Regar
Nico R.A. Mollet
Section five: Special groups of patients
Acute coronary syndromes in special groups of patients	97	(12)
Piero O. Bonetti
Michael J. Zellweger
Christoph Kaiser
Matthias E. Pfisterer
Section six: Pharmacological treatment
Antiischemic treatment (nitrates, β-blockers, calcium antagonists)	109	(7)
David McCarty
Colum G. Owens
A.A. Jennifer Adgey
Antiplatelet therapies: aspirin, thienopyridines, and glycoprotein IIb/IIIa receptor inhibitors	116	(23)
Jaydeep Sarma
Keith A.A. Fox
Antithrombin drugs: LMWH, unfractionated heparin, direct thrombin inhibitors	139	(13)
Raphaelle Dumaine
Gilles Montalescot
Statin therapy in ACS	152	(13)
Francois Schiele
Section seven: Myocardial revascularization
Percutaneous coronary interventions and stenting/CABG in non-ST-segment elevation acute coronary syndromes	165	(22)
Nicolas Meneveau
Jean-Pierre Bassand
Section eight: Therapeutic strategy
Risk stratification and therapeutic strategy	187	(12)
Christian W. Hamm
Indication for revascularization in non-ST-elevation acute coronary syndrome	199	(12)
Lars Wallentin
Management of patients with nonamenable lesions for myocardial revascularization	211	(14)
Victor Legrand
Non-ST-segment elevation coronary syndromes: European Society of Cardiology guidelines	225	(11)
Michel E. Bertrand
Non-ST-segment elevation acute coronary syndromes: ACC/AHA guidelines	236	(12)
Pierre Theroux
From guidelines to registries	248	(13)
Luigi Tavazzi
Section nine: Secondary prevention
Secondary prevention after acute episode of patients presenting with nonpersistent ST-segment elevation	261	(9)
Michel E. Bertrand
How to detect vulnerable plaque	270	(11)
Dirk Boese
Raimund Erbel
Local versus systemic prevention treatment	281	(13)
Mario Togni
Bernhard Meier
Conclusions	294	(1)
Index	295