Introduction | |
Effectiveness of acute pain management | |
Adverse effects of undertreated severe acute pain | |
Acute pain management and patient outcomes | |
Organizational Considerations: Education Standardization | |
Acute pain services | |
Assessment of the Patient With Acute Pain: Assessment of pain and pain relief | |
Assessment of adverse effects | |
Pharmacology of Opioids: Mechanisms of action | |
Effects of opioids | |
Predictors of opioid dose | |
Titration of opioid dose | |
Commonly used opioid agonists | |
Partial agonists and agonist-antagonists | |
Opioid antagonists | |
Pharmacology of Local Anesthetic Drugs: Mechanism of action | |
Efficacy of local anesthetic drugs | |
Adverse effects of local anesthetic drugs | |
Commonly used local anesthetic drugs | |
Non-Opioid and Adjuvant Analgesic Agents: Paracetamol (acetaminophen) | |
Non-selective non-steroidal anti-inflammatory drugs | |
Selective COX-2 inhibitors | |
Nitrous oxide | |
NMDA receptor antagonist drugs | |
a2-Adrenergic agonist drugs | |
Calcitonin | |
Antidepressant drugs | |
Anticonvulsant drugs | |
Membrane-stabilizing drugs | |
Routes of Systemic Opioid Administration: Oral route | |
Intramuscular and subcutaneous routes | |
Intravenous route | |
Rectal route | |
Transdermal route | |
Transmucosal routes | |
Patient-Controlled Analgesia: Equipment Analgesic and other drugs used with PCA | |
The PCA 'prescription' | |
Requirements for the safe management of PCA | |
Management of inadequate analgesia | |
'Step-down' analgesia | |
Complications of PCA | |
Alternative systemic routes of PCA administration | |
Epirural and Intrathecal Analgesia: Anatomy | |
Contraindications | |
Drugs used for epidural analgesia | |
Requirements for the safe management of epidural analgesia | |
Patient-controlled epidural analgesia | |
Management of inadequate analgesia | |
'Step-down' analgesia | |
Complications and side effects of epidural analgesia | |
Concurrent anticoagulant or antiplatelet medications | |
Intrathecal analgesia | |
Other Regional and Local Analgesia: Continuous peripheral nerve blockade | |
Intra-articular analgesia | |
Wound infiltration | |
Topical analgesia | |
Non-Pharmacological Therapies: Psychological interventions | |
Transcutaneous electrical nerve stimulation | |
Acupuncture | |
Physical interventions | |
Acute Neuropathic and Persistent Postacute Pain: Pathophysiology of neuropathic pain | |
Clinical features of neuropathic pain | |
Acute neuropathic pain syndromes | |
Treatment of acute neuropathic pain | |
Progression of acute to persistent pain | |
Preventive analgesia | |
Non-Surgical Acute Pain: Burns injury | |
Spinal cord injury | |
Specific medical conditions | |
More Complex Patients: Elderly patients | |
Opioid-tolerant patients | |
Patients with a substance abuse disorder | |
Patients with obstructive sleep apnea | |
Pregnant or lactating patients | |
Patients with renal or hepatic impairment | |
Self-Assessment Questions | |
Index | |
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