The Advanced Handbook of Methods in Evidence Based Healthcare

by Andrew Stevens

• ISBN13: 9780761961444
• ISBN10: 0761961445
• Format: Hardcover
• Copyright: 2001-03-20
• Publisher: Sage Publications Ltd

Summary

'This handbook is an excellent reflection of the growing maturity and methodological sophistication of the field of Health Technology Assessment. The Handbook covers a spectrum of issues, from primary evidence (clinical trials) through reviews and meta-analysis, to identifying and filling gaps in the evidence. Up-to-date, clearly written, and well-edited, the handbook is a needed addition to any personal or professional library dealing with Health Technology Assessment.'Professor David Banta, TNO Prevention and Health, The Netherlands'This text presents the most advanced knowledge on methodology in health care research, and will form the backbone of many future studies' - Paula Roberts, Nurse ResearcherThe 'effectiveness revolution' both in research and clinical practice, has tested available methods for health services research to the extreme. How far can observational methods, routine data and qualitative methods be used in health care evaluation? What cost and outcome measures are appropriate, and how should data be gathered?With the support of over two million pounds from the British Health Technology Assessment Research Programme, the research project for this Handbook has led to both a synthesis of all of the existing knowledge in these areas and an agenda for future debate and research.The chapters and their authors have been selected through a careful process of peer review and provide a coherent and complete approach to the field. The handbook has been a unique collaboration between internationally regarded clinicians, statisticians, epidemiologists, social scientists, health economists and ethicists. It provides the most advanced thinking and the most authoritative resource for a state of the art review of methods of evaluating health care and will be required reading for anyone involved in health services research and management.

Table of Contents

Contributors	ix
Introduction Methods in Evidence Based Healthcare and Health Technology Assessment: An Overview	1	(6)
Andrew Stevens
Ray Fitzpatrick
Keith Abrams
John Brazier
Richard Lilford
Part I Clinical Trials
Introduction	7	(4)
Richard Lilford
Andrew Stevens
Ethical Issues in the Design and Conduct of Randomised Controlled Trials	11	(14)
Richard J. Lilford
Sarah J.L. Edwards
David A. Braunholtz
Jennifer Jackson
Jim Thornton
Jenny Hewison
Ethics of Clinical Trials: Social, Cultural and Economic Factors	25	(13)
Richard E. Ashcroft
Factors that Limit the Number, Progress and Quality of Randomised Controlled Trials: A Systematic Review	38	(18)
Sue Ross
Carl E. Counsell
William J. Gillespie
Adrian M. Grant
Robin J. Prescott
Ian T. Russell
Iain R. Colthart
Sandra Kiauka
Daphne Russell
Sue M. Shepherd
Results of Clinical Trials and Systematic Reviews: To Whom Do They Apply?	56	(17)
Dianne O'Connell
Paul Glasziou
Suzanne Hill
Jasminka Sarunac
Julia Lowe
David Henry
The Placebo Effect: Methodological Process and Implications of a Structured Review	73	(22)
Rosemary Crow
Heather Gage
Sarah Hampson
Jo Hart
Alan Kimber
Hilary Thomas
Part II Observational and Qualitative Methods
Introduction	91	(4)
Ray Fitzpatrick
Randomised and Non-Randomised Studies: Threats to Internal and External Validity	95	(21)
Colin Sanderson
Martin McKee
Annie Britton
Nick Black
Klim McPherson
Chris Bain
A Review of Observational, Quasi-Experimental and Randomised Study Designs for the Evaluation of the Effectiveness of Healthcare Interventions	116	(20)
Barnaby C. Reeves
Rachel R. MacLehose
Ian M. Harvey
Trevor A. Sheldon
Ian T. Russell
Andrew M.S. Black
The Potential Use of Routine Datasets in Health Technology Assessment	136	(13)
James Raftery
Andrew Stevens
Paul Roderick
Using Routine Data to Complement and Enhance the Results of Randomised Controlled Trials	149	(17)
James D. Lewsey
Gordon D. Murray
Alastair H. Leyland
F. Andrew Boddy
Qualitative Methods in Health Technology Assessment	166	(15)
Elizabeth Murphy
Robert Dingwall
Part III Measurement of Benefit And Cost
Introduction	179	(2)
John Brazier
Criteria for Assessing Patient Based Outcome Measures for Use in Clinical Trials	181	(14)
Ray Fitzpatrick
Claire Davey
Martin J. Buxton
David R. Jones
The Use of Health Status Measures in Economic Evaluation	195	(20)
John Brazier
Mark Deverill
Colin Green
Collecting Resource Use Data for Costing in Clinical Trials	215	(16)
Katharine Johnston
Martin J. Buxton
David R. Jones
Ray Fitzpatrick
Eliciting Time Preferences for Health	231	(16)
John Cairns
Marjon van der Pol
The Conduct and Design of Questionnaire Surveys in Healthcare Research	247	(28)
Elaine McColl
Ann Jacoby
Lois Thomas
Jennifer Soutter
Claire Bamford
Nick Steen
Roger Thomas
Emma Harvey
Andrew Garratt
John Bond
Part IV Analytical Methods
Introduction	273	(2)
Keith R. Abrams
Bayesian Methods	275	(20)
David J. Spiegelhalter
Jonathan P. Myles
David R. Jones
Keith R. Abrams
Methods for Evaluating Organisation- or Area-Based Health Interventions	295	(19)
Martin Gulliford
Obioha C. Ukoumunne
Susan Chinn
Jonathan Sterne
Peter Burney
Allan Donner
Handling Uncertainty in Economic Evaluation	314	(24)
Andrew H. Briggs
Alastair M. Gray
A Review of the Use of the Main Quality of Life Measures, and Sample Size Determination for Quality of Life Measures, Particularly in Cancer Clinical Trials	338	(14)
Michael J. Campbell
Steven A. Julious
Sarah J. Walker
Steve L. George
David Maching
Simultaneous Analysis of Quality of Life and Survival Data	352	(19)
Lucinda J. Billingham
Keith R. Abrams
David R. Jones
Part V Consensus, Reviews And Meta-Analysis
Introduction	367	(4)
Andrew Stevens
Keith R. Abrams
Publication and Related Biases	371	(20)
Fujian Song
Alison Eastwood
Simon Gilbody
Lelia Duley
Alex Sutton
Meta-Analysis in Health Technology Assessment	391	(18)
Alexander J. Sutton
David R. Jones
Keith R. Abrams
Trevor A. Sheldon
Fujian Song
Assessing the Quality of Reports of Randomised Trials Included in Meta-Analyses: Attitudes	409	(17)
Practice
Evidence
David Moher
Terry P. Klassen
Alison L. Jones
Ba' Pham
Deborah J. Cook
Alejandro R. Jadad
Peter Tugwell
Michael Moher
Consensus Development Methods, and their Use in Creating Clinical Guidelines	426	(25)
Nick Black
Maggie Murphy
Donna Lamping
Martin McKee
Colin Sanderson
Janet Askham
Theresa Marteau
Part VI Identifying And Filling Gaps In The Evidence
Introduction	449	(2)
Andrew Stevens
Identifying New Healthcare Technologies	451	(20)
Glenn Robert
Andrew Stevens
John Gabbay
Timing of Assessment of Fast-Changing Health Technologies	471	(14)
Graham Mowatt
Adrian M. Grant
D. Jane Bower
John A. Brebner
John A. Cairns
Lorna McKee
Preliminary Economic Evaluation of Health Technologies	485	(14)
Gareth Harper
Joy Townsend
Martin Buxton
Index	499