This text presents nutrition at the biochemical and metabolic level and covers the biochemistry of vitamins, minerals, and energy nutrients. Written specifically for the advanced nutrition course, this text continues to be the hallmark text used in the majority of courses across the country due to its selected topic coverage at the appropriate level.

1. THE CELL: A MICROCOSM OF LIFE
Components of Typical Cells
Cellular Proteins
Apostosis
Perspective: Cellular Enzymes on the Loose: Indicators of Disease
2. THE DIGESTIVE SYSTEM: MECHANISM FOR NOURISHING THE BODY
An Overview of the Structure of the Digestive Tract
Coordination and Regulation of the Digestive Process
The Process of Digestion: Secretions and Enzymes Required for Nutrient Digestion
Perspective: An Overview of Selected Disorders of the Digestive System with Implications for Nourishing the Body
3. ENERGY TRANSFORMATION
Energy Release or Consumption in Chemical Reactions
The Role of High-Energy Phosphate in Energy Storage
The High Energy Phosphate Bond
Coupled Reactions in the Transfer of Energy
Formation of ATP
Biological Oxidation and the Electron Transport Chain
Perspective: If Oxidation and Phosphorylation Disconnect: A Waste of Energy! 4. CARBOHYDRATES
Structural Features
Digestion
Absorption, Transport, and Distribution
Integrated Metabolism in Tissues
Regulation of Metabolism
Ethyl Alcohol: Metabolism and Biochemical Impact
Perspective: Hypoglycemia: Fact or Fall Guy
5. DIETARY FIBER
Definition of Dietary Fiber
Plants and Fiber
Chemistry and Intraplant Functions of Fiber Components
Selected Properties of Dietary Fiber and Selected Physiologic and Metabolic Effects
Recommended Intake of Fiber: Implications in Disease Prevention and/or Management
Perspective: Treating or Reducing the Risk of Heart Disease, Cancer, Gastrointestinal Disorders: Do Herbal Supplements Have a Role? 6. LIPIDS
Structure and Function
Digestion
Absorption
Transport
Lipids, Lipoproteins, Cardiovascular Disease Risk
Integrated Metabolism in Tissues
Regulation of Lipid Metabolism
Brown Fat Thermogenesis
Non-Digestible, Non-Absorbable Fat Substitute: Olestra
Perspective: The Role of Lipids and Lipoproteins in Artherogenesis
7. PROTEIN
Functional Categories
Protein Structure and Organization
Amino Acid Classification
Sources of Protein
Digestion and Absorption
Amino Acid Metabolism
Interorgan Flow of Amino Acids and Organ-Specific Metabolism
Synthesis and Catabolism of Tissue Proteins
Protein Quality and Protein Intake
Perspective: Protein Turnover: Starvation Versus Stress
8. INTEGRATION AND REGULATION OF METABOLISM
Interrelationship of Carbohydrate, Lipid, and Protein Metabolism
The Central Role of the Liver in Metabolism
Tissue-Specific Metabolism During the Feed-Fast Cycle
System Integration and Homeostasis
Sports Nutrition
Perspective: Diabetes: Metabolism Out of Control
9. THE WATER-SOLUBLE VITAMINS
Perspective: Nutrient Controls on Gene Expression
10. THE FAT-SOLUBLE VITAMINS
Perspective: The Antioxidant Nutrients
11. MACROMINERALS
Perspective: Macrominerals and Hypertension
12. MICROMINERALS
Perspective: Hypoferremia and Infection: When Are Iron Supplements Advisable? 13. ULTRATRACE ELEMENTS
14. BODY FLUID AND ELECTROLYTE BALANCE
Water Distribution in the Body
Maintenance of Fluid Balance
Maintenance of Electrolyte Balance
Acid-Base Balance: The Control of Hydrogen Ion Concentration
Acid-Base Buffers
Respiratory Regulation of pH
Renal Regulation of pH
Perspective: Fluid Balance and the Thermal Stress of Exercise
15. BODY CONSUMPTION AND ENERGY EXPENDITURE
Body Weight: What Should We Weigh? The Composition of the Human Adult Body
Methods for the Measurement of Body Composition
Primary Influences on Body Composition
Components of Energy Expenditure
Assessment of Energy Expenditure
Perspectives: Diet and Diet-Related Factors Associated with Osteoporosis Eating Disorders
16. NUTRITION AND THE CENTRAL NERVOUS SYSTEM
Nutrient Precursors of Neurotransmitters
Sugar
Caffeine
Glutamic Acid and Monosodium Glutamate
Aspartame
CNS-Stimulating Hormones in Weight Control: Leptin and Insulin
Perspective: Attention Deficit Hyperactivity Disorder (ADHD) in Children
17. EXPERIMENTAL DESIGN AND CRITICAL INTERPRETATION OF RESEARCH
The Scientific Method
The Influence of Knowledge Base and Technology on Research: A Historical Example
Research Methodologies
Terms That Describe Research Quality
Initiation of Research
Problems and Pitfalls in Research
Evaluation of Research and Scientific Literature

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