Advances in Heterocyclic Chemistry

by Katritzky

• ISBN13: 9780120207657
• ISBN10: 0120207656
• Edition: 1st
• Format: Hardcover
• Copyright: 1996-07-23
• Publisher: Elsevier Science

Summary

Praise for the Series: "The typesetting, arrangement of references, and drafting of structural formulas adhere to the high standards of this series and provide a model for good publishing...The content is, as to be expected, excellent." --Journal of the American Chemical Society Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area - one of great importance to organic chemists, polymer chemists, and many biological scientists.

Table of Contents

Contributors	vii
Preface	ix
The t-Amino Effect: Heterocycles Formed by Ring Closure of ortho-Substituted t-Anilines
Otto Meth-Cohn
Introduction	1	(2)
Reactions: Formation of Five-Membered Rings from t-Amino-Effect Reactions	3	(15)
Reactions: Formation of Six-Membered Rings from t-Amino-Effect Reactions	18	(8)
Reactions: Formation of Rings Containing More Than Six-Members from t-Amino-Effect Reactions	26	(1)
Reactions: Reaction of ortho-Substituents at the t-Amino Nitrogen	27	(5)
Reactions: Trapping of Oxidatively Derived ortho-Iminium Salts	32	(1)
Concluding Remarks	33	(7)
References	34	(6)
Ring Contraction of Heterocycles by Sulfur Extrusion
Matthias Bohle
Jurgen Liebscher
Introduction	40	(5)
Six-Membered Rings from Seven-Membered Rings	45	(9)
Five-Membered Rings from Six-Membered Rings	54	(17)
Four-Membered Rings from Five-Membered Rings	71	(5)
Three-Membered Rings from Four-Membered Rings	76	(1)
Miscellaneous	76	(18)
References	83	(11)
Carbenes and Carbenoids in Synthesis of Heterocycles
A. F. Khlebnikov
M. S. Novikov
R. R. Kostikov
Introduction	94	(1)
General Carbene routes to Heterocycles	95	(3)
Synthesis of Rings with One Nitrogen Atom	98	(36)
Synthesis of Rings with One Oxygen Atom	134	(27)
Synthesis of Rings with One Sulfur Atom	161	(8)
Synthesis of Rings with One Other Heteroatom	169	(2)
Synthesis of Rings with Two Heteroatoms	171	(24)
Synthesis of Rings with Three or More Heteroatoms	195	(5)
Synthesis of Bridged Heterocyclic Systems	200	(16)
Conclusion	216	(20)
References	216	(20)
Thienopyrimidines: Synthesis, Reactions, and Biological Activity
Yehia A. Ibrahim
Ahmed H. M. Elwahy
Azza M. Kadry
Introduction	236	(1)
Structure	237	(1)
Synthetic Approaches to Thieno[2,3-d]pyrimidines	237	(13)
Reactions of Thieno[2,3-d]pyrimidines	250	(4)
Synthetic Approaches to Thieno[3,2-d]pyrimidines	254	(4)
Reactions of Thieno[3,2-d]pyrimidines	258	(3)
Synthetic Approaches to Thieno[3,4-d]pyrimidines	261	(3)
Reactions of Thieno[3,4-d]pyrimidines	264	(2)
Biological Activity	266	(17)
References	268	(15)
Cycloadditions and Reactions of Oxa-Aromatics with Nucleophiles
Katsuo Ohkata
Kin-Ya Akiba
Introduction	283	(1)
Reactions of Pyrylium Salts and Pyrones with Nucleophiles	284	(33)
Annulation Reactions in Pyrylium Salts and Pyrone Derivatives	317
References	366