The African Trypanosomes

by Black, Samuel J.; Seed, J. Richard

• ISBN13: 9780792375128
• ISBN10: 0792375122
• Format: Hardcover
• Copyright: 2002-01-01
• Publisher: Kluwer Academic Pub

Summary

African trypanosomes are tsetse-transmitted protozoa that inhabit the extracellular compartment of host blood. They cause fatal sleeping sickness in people, and Nagana, a wasting and generally fatal disease, in cattle. While trypanosomes are most common to Africa (about 30% of Africa's cattle graze on the fringe of the tsetse habitat), some species have spread beyond its boarders to Asia, the Middle East and South America. The African Trypanosomes , volume one of World Class Parasites , is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

Table of Contents

Preface	vii
African Trypanosomiasis. Failure of Science and Public Health	1	(10)
D. Molyneux
The Programme Against African Trypanosomiasis Information System (PAATIS).	11	(14)
M. Gilbert
C. Jenner
J. Pender
D. Rogers
J. Slingenbergh
W. Wint
Effects of Climate, Human Population and Socio-Economic Changes on Tsetse-Transmitted Trypanosomiasis to 2050.	25	(14)
J.J. McDermott
P.M. Kristjanson
R.L. Kruska
R.S. Reid
T.P. Robinson
P.G. Coleman
P.G. Jones
P.K. Thornton
Tsetse Vector Based Strategies for Control of African Trypanosomiasis.	39	(12)
S. Aksoy
Diagnosis of Human and Animal African Trypanosomiasis	51	(14)
P. Buscher
Chemotherapy of African Trypanosomiasis.	65	(14)
J.R. Seed
D.W. Boykin
Immunobiology of African Trypanosomiasis - New Paradigms, Newer Questions.	79	(18)
J.M. Mansfield
T.H. Davis
M.E. Dubois
Identifying the Mechanisms of Trypanotolerance in Cattle.	97	(16)
J. Naessens
D.J. Grab
M. Sileghem
Trypanosome Factors Controlling Population Size and Differentiation Status.	113	(14)
N.B. Murphy
T. Olijhoek
The Endocytic Machinery of Bloodstream Stage African Trypanosomes.	127	(16)
D. Nolan
J.A. Garcia-Salcedo
M. Geuskens
D. Salmon
F. Paturiaux-Hanocq
A. Pays
P. Tebabi
E. Pays
The Genome of the African Trypanosome.	143	(16)
J.E. Donelson
Towards a Trypanosomiasis Vaccine.	159	(16)
S.J. Black
N.B. Murphy
D.P. Nolan
Epilogue	175	(2)
Index	177