Alzheimer's Disease: Targets for New Clinical Diagnostic and Therapeutic Strategies

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  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2012-04-26
  • Publisher: CRC Press

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This collection of articles written by international Alzheimer's experts is intended to provide a detailed synopsis of the current state-of-the-art of Alzheimer's Disease across many disciplines. A discussion of current biophysical models and hypotheses regarding the pathology of AD serves as a foundation for a review of research models of AD and recent advances in the fields of in vivo and in vitro AD diagnostics. Experts weigh in on how research advances and accurate diagnostics pave the way for a robust pipeline of therapeutics to combat not only Alzheimer's Disease, but other neurodegenerative diseases via a myriad of different approaches.

Table of Contents

Prefacep. xiii
Frontiers in Neurosciencep. xv
About the Editorsp. xvii
Contributorsp. xix
The Amyloid -Protein and Alzheimer's Diseasep. 1
Emerging Principles and Biomarkers in In Vitro Diagnostics for Alzheimer's Diseasep. 87
Imaging Biomarkers for Diagnosis, Prognosis, and Treatment of Alzheimer's Diseasep. 103
The Current Status of Alzheimer's Disease Treatment: Why We Need Better Therapies and How We Will Develop Themp. 117
New Small Molecule Drug Discovery for Alzheimer's Diseasep. 163
Alzheimer's Disease: Clinical Aspectsp. 211
Pathogenic Protein Strains as Diagnostic and Therapeutic Targets in Alzheimer's Diseasep. 231
Traumatic Brain Injury in the Development of Alzheimer's Disease: Risk Factors, Diagnosis, and Treatment Strategiesp. 249
Indexp. 271
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