Amino Acids, Peptides and Proteins in Organic Chemistry, Origins and Synthesis of Amino Acids

by Hughes, Andrew B.

• ISBN13: 9783527320967
• ISBN10: 3527320962
• Edition: 1st
• Format: Hardcover
• Copyright: 2009-09-28
• Publisher: Wiley-VCH

Summary

Closing a gap in the literature, this is the only open book series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, this series is a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures.

Author Biography

Andrew Hughes is a Reader and Head of the Department of Chemistry, La Trobe University, Melbourne, Australia. He obtained his degrees from the University of Western Australia. Post-doctoral appointments at the University of Cambridge starting 1989 included 3 years working with Professor Andrew Holmes before joining Professor Steven Ley's group in 1993. While at Cambridge he was appointed the Shell Research Fellow at Robinson College.

Table of Contents

Amino Acid Origins

Primitive Amino Acid Chemistry Extraterrestrial Amino Acids Terrestrial Amino Acids and Their Evolution

The Common alpha-Amino Acids; Proteinogenic Amino Acid Biosynthesis Uncommon alpha-Amino Acid;

Non-Proteinogenic Amino Acid Biosynthesis beta-Amino Acid Biosynthesis

Synthesis Of Amino Acids

Common or Proteinogenic alpha-Amino Acids Fermentation Production of alpha-Amino Acids Radical Synthetic

Methods for alpha-Amino Acids Uncommon or Non-Proteinogenic alpha-Amino Acids Synthesis of Non-Coding

Amino Acids Synthesis of N-Alkyl Amino Acids Synthesis of beta-Amino Acids Synthesis of Alicyclic beta-Amino Acids

Synthesis of alpha,beta-Diamino Acids Synthesis of Halogenated Amino Acids Synthesis of Isotopically Labelled Amino

Acids Synthesis of Unnatural/Non-proteinogenic alpha-Amino Acids Synthesis of gamma- and delta-Amino Acids Synthesis of GABA and Amino Acid-Based

GABA analogues Synthesis and Chemistry of alpha,beta-Dehydroamino Acids Synthesis and Chemistry of Hydrazino Acids Synthesis and Chemistry of Hydroxamic

Acids (N-Hydroxy Amino Acids) Chemistry of Aminoboronic Acids Chemistry of alpha-Aminophosphonic Acids and Phosphonopeptides

Chemistry of alpha-Silyl Amino Acids Use of Enzymes in Synthesis of Amino Acids

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