Amino Acids, Peptides and Proteins in Organic Chemistry, Modified Amino Acids, Organocatalysis and Enzymes

by Hughes, Andrew B.

• ISBN13: 9783527320981
• ISBN10: 3527320989
• Edition: 1st
• Format: Hardcover
• Copyright: 2009-10-26
• Publisher: Wiley-VCH

Summary

Closing a gap in the literature, this is the only open book series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, this series is a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures.

Author Biography

Andrew Hughes is a Reader and Head of the Department of Chemistry, La Trobe University, Melbourne, Australia. He obtained his degrees from the University of Western Australia. Post-doctoral appointments at the University of Cambridge starting 1989 included 3 years working with Professor Andrew Holmes before joining Professor Steven Ley's group in 1993. While at Cambridge he was appointed the Shell Research Fellow at Robinson College.

Table of Contents

Amino Acid Organocatalysis

Catalysis of Reactions by Amino Acids

Catalysis of Reactions by Small Peptides

Enzymes

Enzymic Mechanisms of Catalysis

The Chemistry of Proteases

Semi-Synthetic Enzymes

Non-Enzymic Mechanisms of Catalysis

Substrate Recognition

Protein Recognition

Non-Ribosomal Peptide Synthesis

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