Angiogenesis and Cardiovascular Disease

by Ware, J. Anthony; Simons, Michael

ISBN13:
9780195112351
ISBN10:
0195112350
Format: Hardcover
Copyright: 1999-01-07
Publisher: Oxford University Press
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Summary

Angiogenesis and Cardiovascular Disease provides a comprehensive review of the basic scientific and clinical advances in the field of angiogenesis, and its role in the human cardiovascular system. The material presented draws from multiple disciplines, integrating information in a singlesource. Topics addressed focus first on aspects of development and normal biology of the vasculature, and then on angiogenesis and how it is involved in the pathophysiology and therapy of ischemic cardiovascular disease. Vascular development, endothelial cell biology, the vascular matrix, and growthfactors are discussed. Up to date information on current clinical trials, and practical advice concerning application to cardiovascular therapeutic options, are also stressed.

Contributors

Part I Developmental and Normal Biology of the Vasculature

Embryonic Development of the Vascular System

(27)

Antonis K. Hatzopoulos

Robert D. Rosenberg

Cellular Mechanisms of Angiogenesis

(30)

J. Anthony Ware

Heparan Sulfate Proteoglycans

(19)

Nicholas W. Shworak

Robert D. Rosenberg

Molecular Mechanisms of the Fibroblast Growth Factor Family

(22)

Kurt A. Engleka

Thomas Maciag

The Vascular Endothelial Growth Factor Family

101

(27)

Napoleone Ferrara

Hans Peter Gerber

Platelet-Derived Growth Factor and Other Modulators of Angiogenesis

128

(15)

Thomas F. Deuel

Part II Angiogenesis in the Pathophysiology and Treatment of Ischemic Vascular Disease

Angiogenesis in Atherosclerosis and Restenosis

143

(16)

Mark Post

J. Anthony Ware

Collateral Circulation of the Heart

159

(40)

Wolfgang Schaper

Jan J. Piek

Ramon Munoz-Chapuli

Claudia Wolf

Wulf Ito

Angiogenesis in Nonischemic Myocardium

199

(14)

Robert J. Tomanek

Animal Models of Angiogenesis in Cardiovascular Tissues

213

(25)

J. Gary Meszaros

Laurence L. Brunton

Colin M. Bloor

Growth Factor Delivery Strategies

238

(20)

Chun Yu

Anthony English

Elazer R. Edelman

Coronary Microcirculation and Angiogenesis

258

(31)

Frank W. Sellke

David G. Harrison

Therapeutic Angiogenesis in Myocardial Ischemia

289

(32)

Michael Simons

Roger J. Laham

Therapeutic Angiogenesis in Peripheral Limb Ischemia

321

(22)

Jeffrey M. Isner

Ann Pieczek

Robert Schainfeld

Richard Blair

Laura Haley

Takayuki Asahara

Index

343

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